Fibrosis Research: Methods and Protocols / Edition 1

Hardcover (Print)
Buy New
Buy New from
Used and New from Other Sellers
Used and New from Other Sellers
from $15.95
Usually ships in 1-2 business days
(Save 91%)
Other sellers (Hardcover)
  • All (11) from $15.95   
  • New (10) from $15.95   
  • Used (1) from $230.16   


Fibrosis Research: Methods and Protocols contains a wealth of information concerning fibrosis research. Topics covered in the text include: ECM Regulation, Animal models of fibrosis, and the Genetic approaches to fibrosis.

Read More Show Less

Editorial Reviews

From the Publisher
"...a must for the shelf of every researcher and physician interested in fibrotic diseases." -Rheumatology
Read More Show Less

Product Details

  • ISBN-13: 9781588294791
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 8/28/2005
  • Series: Methods in Molecular Medicine Series, #117
  • Edition description: 2005
  • Edition number: 1
  • Pages: 392
  • Product dimensions: 6.20 (w) x 9.30 (h) x 1.10 (d)

Table of Contents

Part I. The Clinical Scope of Fibrosis

Pulmonary Fibrosis
David A. Zisman, Michael P. Keane, John A. Belperio, Robert M. Strieter, and Joseph P. Lynch, III

Renal Fibrosis
H. William Schnaper

Transforming Growth Factor-b: A Key Mediator of Fibrosis
Alain Mauviel

Part II. Regulation of Extracellular Matrix Metabolism: Cultured Cells

Isolation and Culture of Skin Fibroblasts
Laure Rittié and Gary J. Fisher

Isolation and Culture of Hepatic Stellate Cells
Ralf Weiskirchen and Axel M. Gressner

Isolation and Phenotypic Characterization of Lung Fibroblasts
Carolyn J. Baglole, Sireesha Y. Reddy, Stephen J. Pollock, Steven E. Feldon, Patricia J. Sime, Terry J. Smith, and Richard P. Phipps

Methods for Measuring Type I Collagen Synthesis In Vitro
David C. Rishikof, Ping-Ping Kuang, Mangalalaxmy Subramanian, and Ronald H. Goldstein

Methods for Assessing the Molecular Mechanisms Controlling Gene Regulation
Richard A. Rippe and Branko Stefanovic

Methods for Measuring TGF-b Using Antibodies, Cells, and Mice
Vladimir Jurukovski, Branka Dabovic, Vesna Todorovic, Yan Chen, and Daniel B. Rifkin

Part III. Studying Fibrosis Using Animal Models

Morphological Methods for Assessment of Fibrosis
Rakesh K. Kumar

Methods for Measuring Hydroxyproline and Estimating In Vivo Rates of Collagen Synthesis and Degradation
Robin J. McAnulty

Approaches to Evaluation of Fibrogenic Pathways in Surgical Lung Biopsy Specimens
Cory M. Hogaboam, Kristin J. Carpenter, Holly Evanoff, and Steven L. Kunkel

Animal Models for Adult Dermal Wound Healing
Mary Birch, Annette Tomlinson, and Mark W. J. Ferguson

Modeling Liver Fibrosis in Rodents
Christothea Constandinou, Neil Henderson, and John P. Iredale

Animal Models of Pulmonary Fibrosis
MehrnazGharaee-Kermani, Matthew Ullenbruch, and Sem H. Phan

Animal Models of Renal Fibrosis
Michael Zeisberg, Mary A. Soubasakos, and Raghu Kalluri

Animal Models of Cardiac Fibrosis
Yao Sun and Karl T. Weber

Part IV. Genetic Approaches to Studying Fibrosis

Finding Fibrosis Genes: The Lung
Lauranell H. Burch and David A. Schwartz

Genetic Studies to Identify Hepatic Fibrosis Genes and SNPs in Human Populations
Christopher Paul Day

Analysis of Microarray Experiments for Pulmonary Fibrosis
Nilesh B. Davé and Naftali Kaminski

DNA Microarrays and Data Mining to Study Hepatic Fibrosis
Bernd Schnabl, Youkyung Hwang Choi, Curt H. Hagedorn, and Ramón Bataller

Analysis of Proteins Dominantly Expressed in Hepatic Stellate Cells of Activated Phenotype: The Molecular Approach for Liver Fibrosis
Norifumi Kawada


Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)