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Flavonoids In Health And Disease, Second Edition, / Edition 2

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Revised and expanded, this blue-ribbon reference emphasizes the latest developments in the identification, utilization, and analysis of flavonoids for the prevention of disease and maintenance of good health. The book examines the processes involved in the absorption, metabolism, distribution, and excretion of these compounds and the impact of biotransformation on flavonoid function.The Second Edition contains new discussions on the potential of dietary flavonoids to attenuate neurological dysfunction and degeneration, developments in gene expression and genomics for identification of therapeutic targets and markers of disease, and the mechanisms regulating flavonoid bioavailability.

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Product Details

  • ISBN-13: 9780824742348
  • Publisher: CRC Press
  • Publication date: 5/1/2003
  • Series: Antioxidants in Health and Disease Series
  • Edition description: Revised
  • Edition number: 2
  • Pages: 504
  • Product dimensions: 6.14 (w) x 9.21 (h) x 1.06 (d)

Table of Contents

Series Introduction
1 Phenolic Acids in Fruits and Vegetables 1
2 Flavonoids in Herbs 43
3 The Relationship Between the Phenolic Composition and the Antioxidant Activity of Fruits and Vegetables 71
4 Applications of Flavonoid Analysis and Identification Techniques: Isoflavones (Phytoestrogens) and 3-Deoxyanthocyanins 97
5 Synthesis, Identification, Quantification and Chemical Reactivity of Methylated Flavan-3-ols 123
6 Investigation of Flavonoids and Their In Vivo Metabolite Forms Using Tandem Mass Spectrometry 145
7 Effects of Flavonoids on the Oxidation of Low-Density Lipoprotein and Atherosclerosis 165
8 Phytochemicals and Brain Aging: A Multiplicity of Effects 205
9 Flavonoids: Neuroprotective Agents? Modulation of Oxidative Stress Induced MAP Kinase Signal Transduction 233
10 Mitochondrial Actions of Flavonoids and Isoflavonoids 273
11 Gene Modulation of HaCaT Cells Induced by Pine Bark Extract 303
12 Cytoprotective and Cytotoxic Effects of Flavonoids 309
13 Understanding the Bioavailability of Flavonoids Through Studies in Caco-2 Cells 349
14 Metabolism in the Small Intestine and Gastrointestinal Tract 363
15 Absorption of Quercetin Glycosides 391
16 Bioavailability of Flavanol Monomers 413
17 Absorption and Metabolism of Hydroxycinnamates 441
Index 459
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