Foundations of Clinical Research / Edition 3

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Foundations of Clinical Research: Applications to Practice, 3/e provides the foundations that are necessary for finding and interpreting research evidence across all healthcare professions. This book has been revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, including the growing emphasis on evidence-based practice (EBP) that has become central to all of health care and the new vocabulary that is being integrated into research and practice across disciplines. There is also a new chapter on systematic reviews and meta-analysis as well as expanded content related to clinical decision making, including likelihood ratios, pretest and posttest probabilities, minimally important change and number needed to treat.
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Product Details

  • ISBN-13: 9780131716407
  • Publisher: Prentice Hall
  • Publication date: 1/14/2008
  • Edition description: New Edition
  • Edition number: 3
  • Pages: 912
  • Product dimensions: 7.10 (w) x 9.20 (h) x 2.00 (d)

Meet the Author

Dr. Leslie Portney is the Director of Graduate Programs in Physical Therapy for the MGH Institute of Health Professions. Leslie graduated with a Doctor of Physical Therapy from the MGH Institute, a PhD in Gerontology from Boston University, a Master of Science in Physical Therapy from Medical College of Virginia, and a Certificate in Physical Therapy from the University of Pennsylvania. She is a licensed physical therapist in both New York and Massachusetts. Leslie has authored a multitude of books and has contributed to a variety of different publications including the PT—Magazine of Physical Therapy. Leslie is currently a member of the American Physical Therapy Association and on the Task Force on Uniform Outcomes Assessment.

Dr. Mary Watkins is a Clinical Associate Professor in the Graduate Programs in Physical Therapy for the MGH Institute of Health Professions. Mary graduated with a Doctor of Physical Therapy from the MGH Institute and a Master of Science from Boston University. Mary is a licensed physical therapist in Massachusetts, a member of the American Physical Therapy Association. Mary has authored many book chapters and contributed to a number of different publications including the Journal of Hand Therapy, the Journal of Bone and Joint Surgery, Journal of the American Medical Association, Journal of Occupational Rehabilitation and the Journal of Orthopedic & Sports Physical Therapy.

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Table of Contents

Part I: Foundations of Clinical Research

1. A Concept of Clinical Research

2. The Role of Theory in Clinical Research

3. Ethical Issues in Clinical Research

Part II: Concepts of Measurement

4. Principles of Measurement

5. Reliability of Measurements

6. Validity of Measurements

Part III: Designing Clinical Research

7. Asking the Research Question

8. Sampling

9. Validity in Experimental Design

10. Experimental Designs

11. Quasi-Experimental Designs

12. Single Subject Designs

13. Exploratory Research: Observational Designs

14. Descriptive Research

15. Surveys and Questionnaires

16. Systematic Reviews and Meta-Analyses

Part IV: Data Analysis

17. Descriptive Analysis

18. Statistical Inference

19. Comparing Two Means: The t-test

20. Comparing More Than Two Means: Analysis of Variance

21. Multiple Comparison Tests

22. Nonparametric Tests for Group Comparisons

23. Correlation

24. Regression

25. Measures of Association for Categorical Variables: Chi-Square

26. Statistical Measures of Reliability

27. Statistical Measures of Validity

28. Epidemiology: Measures of Risk

29. Multivariate Analysis

30. Data Management

Part V: Communication

31. Writing a Research Proposal

32. Reporting the Results of Clinical Research

33. Evaluating Research Reports

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