Foundations of Clinical Research: Applications to Practice / Edition 2

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This book serves as a comprehensive reference for a variety of research situations. This edition reflects the popular approaches to analysis and design, and addresses the focus of health-care related research through the 1990s and into the 21st century. Expanded or added topics include outcomes research and the disablement model, validity and diagnostic screening, meta-analysis, scales used in survey and outcomes research, logistic regression, measures of reliability, and data management to prepare for computer analysis. For those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology.

The book contains black-and-white illustrations.

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Editorial Reviews

This is the new edition of a comprehensive reference for both students and health care practitioners, aimed at enhancing critical understanding of published research as well as offering detailed guidance on how to do research. Arrangement is in five parts, each focusing on a different phase of the research process, from concept to dissemination of results. Appendixes offer information of statistical procedures, power analysis, transformation of data, and informed consent. The authors are affiliated with the Massachusetts General Hospital in Boston, Massachusetts. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9780838526958
  • Publisher: Prentice Hall
  • Publication date: 12/17/1999
  • Edition description: Older Edition
  • Edition number: 2
  • Pages: 742
  • Product dimensions: 7.22 (w) x 9.30 (h) x 1.33 (d)

Table of Contents

Pt. I Foundations of Clinical Research 1
Ch. 1 A Concept of Research 3
Ch. 2 The Role of Theory in Clinical Research 21
Ch. 3 Ethical Issues in Clinical Research 33
Pt. II Concepts of Measurement 47
Ch. 4 Principles of Measurement 49
Ch. 5 Reliability 61
Ch. 6 Validity of Measurements 79
Pt. III Design 111
Ch. 7 The Research Question 113
Ch. 8 Sampling 137
Ch. 9 Experimental Control 153
Ch. 10 Experimental Design 177
Ch. 11 Sequential Clinical Trials 203
Ch. 12 Single-Subject Designs 223
Ch. 13 Descriptive and Exploratory Research 265
Ch. 14 Surveys 285
Ch. 15 Epidemiology 317
Ch. 16 Other Research Approaches 345
Pt. IV Analysis 365
Ch. 17 Descriptive Statistics and Measures of Variability 367
Ch. 18 Statistical Inference 387
Ch. 19 The t-Test 413
Ch. 20 Analysis of Variance 427
Ch. 21 Multiple Comparison Tests 453
Ch. 22 Nonparametric Tests for Group Comparisons 473
App. A Statistical Tables 673
App. B Summary of Statistical Procedures 699
App. C Power and Sample Size 705
App. D Transformation of Data 731
App. E Sample Informed Consent Form 735
Glossary of Statistical Symbols and Abbreviations 739
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  • Anonymous

    Posted August 6, 2003

    Good Broad Scope Research Text

    Despite fairly benign practice examples, this text provides a thorough description of research design and basic data anaylsis strategies. The graphical depictions of study designs are especially notable.

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