Frameshift
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Frameshift

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by Robert J. Sawyer
     
 

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Geneticist Pierre Tardivel may not have long to live—he's got a fifty-fifty chance of having the gene for Huntington's disease. But if his DNA is tragic, his girlfriend's is astonishing: Molly Bond has a mutation that gives her telepathy. Both of them have attracted the interest of Pierre's boss, Dr. Burian Klimus, a senior researcher in the Human Genome

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Overview

Geneticist Pierre Tardivel may not have long to live—he's got a fifty-fifty chance of having the gene for Huntington's disease. But if his DNA is tragic, his girlfriend's is astonishing: Molly Bond has a mutation that gives her telepathy. Both of them have attracted the interest of Pierre's boss, Dr. Burian Klimus, a senior researcher in the Human Genome Project who just might be hiding a horrific past. Avi Meyer, a dogged Nazi hunter, thinks Klimus was the monstrous "Ivan the Terrible" of the Treblinka Death Camp. As Pierre races against the ticking clock of his own DNA to make a world-changing scientific breakthrough, Avi also races against time to bring Klimus to justice before the last survivors of Treblinka pass away.

Winner of the Seiun Award—Japan's top honor in science fiction—and a finalist for the Hugo Award, Frameshift is classic Robert J. Sawyer, combining a heart-wrenching human story and cutting-edge science into a pulse-pounding thriller that "delivers the real thing with subtlety and great skill" (Toronto Star).

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Editorial Reviews

From the Publisher

“Filled to bursting with ideas, characters, and incidents.” —The New York Times

“You hardly need me to tell you to buy his latest, Frameshift. You know it's good, you know he gets the techy bits right, and you know he's interesting and thought-provoking.” —Analog

“Robert Sawyer's science fiction is always ambitious, well-written, and imaginative. With each novel he keeps getting better.” —Kevin J. Anderson

“Sawyer has created a gripping medical sf thriller...Highly recommended.” —Library Journal

bn.com
Fascinating as his earlier novels were, Sawyer really hit his stride with The Terminal Experiment. Frameshift continues in a similar vein: thoughtful extrapolations of current scientific and social trends delivered at the pace of a page-turning thriller.
—Charles de Lint
Kirkus Reviews
Another near-future science-fictional thriller from Ontario resident Sawyer (the 1995 Nebula Awardwinning author of The Terminal Experiment, not reviewed). French-Canadian molecular biologist Pierre Tardivel does research for the Human Genome Project in California—and has a 50-50 chance of dying of the incurable genetic Huntington's disease. His girlfriend, psychologist Molly Bond, is a short-range telepath; so when Pierre narrowly escapes being murdered, Molly knows the knife-wielder had in fact been paid to kill Pierre. But why? Well, Pierre discovers that other clients of Condor, his health insurance company, are being eliminated—clients with potentially expensive health problems. Molly, meanwhile, unable to conceive normally, agrees to an IVF procedure conducted free of charge by Pierre's boss, the Nobel laureate Burian Klimus—but he impregnates her with genes extracted from a Neanderthal's bones! Worse still, after a visit from Avi Meyer of the Justice Department, Pierre wonders whether Klimus might be the infamous Ivan the Terrible, of the Treblinka extermination camp!

Conspicuously overplotted and unwieldy—the whole Ivan the Terrible subplot would have been better eliminated—but exciting and engrossing, if increasingly improbable.

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Product Details

ISBN-13:
9780765313164
Publisher:
Tom Doherty Associates
Publication date:
11/01/2005
Pages:
352
Product dimensions:
5.50(w) x 8.50(h) x 0.78(d)

Related Subjects

Meet the Author

Robert J. Sawyer is the Hugo Award-winning author of Hominids, the Nebula Award-winning author of The Terminal Experiment, and the Aurora Award-winning author of FlashForward, basis for the ABC TV series. He is also the author of Calculating God, Mindscan, the WWW series—Wake, Watch and Wonder—and many other books. He was born in Ottawa and lives in Toronto.

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Frameshift 4 out of 5 based on 0 ratings. 2 reviews.
harstan More than 1 year ago
In Berkley, California, French-Canadian research molecular biologist Pierre Tardivel works on the Human Genome Project even as he expects to die soon due to the probability that he suffers from terminal genetic Huntington's disease. His girlfriend psychologist Molly Bond knows Pierre cares deeply for her especially since she has limited telepathic skills. When someone attacks Pierre, Molly realizes that an unknown person hired the assailant to kill Pierre. --- Both wonder why he would be the victim of an assassination attempt. Pierre does what he does best, conduct research seeking trends. He soon learns that his health insurance provider Condor has had an abnormally high number of deaths of those members with potentially expensive health costs that they would have to cover. At the same time Molly, wanting an offspring of Pierre, but unable to conceive naturally accepts the kind offer from Pierre's boss, Nobel Prize winner Burian Klimus to have an IVF impregnation. However, Burian uses the opportunity to test something different as he impregnates Molly with DNA extracted from the remains of a Neanderthal at the same time the Justice Department Agent Avi Meyer warns Pierre that his superior may be Ivan the Terrible of Treblinka infamy. --- This is a reprint of an exciting action-packed medical thriller that grips the audience from the moment readers meet Pierre and never slows down until the final twist. The story line in some ways will remind the audience of Rosemary¿s baby except the devil is am amoral human using modern science to impregnate the innocent woman. Though the ties back to Treblinka seem forced and add nothing (Klimus can be a modern day scientist with no ethics without the concentration camp résumé), readers will finish this thriller in one exciting sitting. --- Harriet Klausner
Guest More than 1 year ago
A good read up until about halfway through. The science and tech parts are just right, and no punches are pulled. But after then, Sawyer's desire to make a political point about the health care system entirely hijacks the book, and murders the plot's plausibility. There were also a few too many convenient plot holes (good thing for the plot that Pierre happened to pick that very HMO, instead of the umpteen million others...). But not a bad book, and worth a read.