Free Radicals in Biology and Medicine / Edition 4

Free Radicals in Biology and Medicine / Edition 4

by Barry Halliwell, John M. C. Gutteridge
     
 

ISBN-10: 0198568681

ISBN-13: 9780198568681

Pub. Date: 04/13/2007

Publisher: Oxford University Press, USA

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins

…  See more details below

Overview

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing.

This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Read More

Product Details

ISBN-13:
9780198568681
Publisher:
Oxford University Press, USA
Publication date:
04/13/2007
Edition description:
REV
Pages:
704
Product dimensions:
9.80(w) x 7.50(h) x 2.00(d)

Table of Contents

List of abbreviations
1Oxygen is a toxic gas - an introduction to oxygen toxicity and reactive oxygen species1
2The chemistry of free radicals and related 'reactive species'36
3Antioxidant defences105
4Oxidative stress: adaptation, damage, repair and death246
5Detection of free radicals and other reactive species: trapping and fingerprinting351
6Reactive species as useful biomolecules430
7Oxidative stress and antioxidant protection: some special cases485
8Free radicals, 'reactive species' and toxicology544
9Free radicals, other reactive species and disease617
10Ageing, nutrition, disease and therapy: a role for antioxidants?784
App. ISome basic chemistry for the life scientist860
App. IISome basic molecular biology for the chemist880
Index899

Read More

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >