Free Radicals in Brain Physiology and Disorders / Edition 1

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1996 Hard cover New. Sewn binding. Cloth over boards. 474 p. Audience: General/trade. BRAND NEW. NO DJ. (as issued)

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Editorial Reviews

Doody's Review Service
Reviewer: Manuel Dujovny, MD (Wayne State University School of Medicine)
Description: The importance of free radicals in neurodegeneration trauma, ischemia, epilepsy, etc. is becoming more evident.
Purpose: This volume represents an update of the knowledge of free radicals in several neurobiological processes.
Audience: This book is aimed at neurobiologists, neurophysiologists, neurologists, neurosurgeons, and neuropharmacologists.
Features: This book resulted from a conference held on free radicals in brain physiology and disorders in Tokyo in August 1995 in celebration of the retirement of Professor Akitane Mori, to whom this book is dedicated. It is divided into seven sections dedicated to the analysis of Guadinino compounds in the brain, free radicals and cell damage, the role of nitric oxide and neuronal disorders, the role of free radicals in the brain, the importance of free radicals in other neurological disorders, stress and environmental effects, and factors related to neurotoxicity. Several new approaches related to the prevention and treatment of free radical-related neurological disorders are well expanded by the contribution of multiple authors. The illustrations are pertinent. The index is appropriate for the content of the book. The overall appearance of the book is good.
Assessment: I found this book to represent a nice review of the importance of free radicals in neurophysiology, and I highly recommend it for neuroscientists, neurologists, neurosurgeons, and neuropharmacologists.
Manuel Dujovny
The importance of free radicals in neurodegeneration trauma, ischemia, epilepsy, etc. is becoming more evident. "This volume represents an update of the knowledge of free radicals in several neurobiological processes. "This book is aimed at neurobiologists, neurophysiologists, neurologists, neurosurgeons, and neuropharmacologists. "This book resulted from a conference held on free radicals in brain physiology and disorders in Tokyo in August 1995 in celebration of the retirement of Professor Akitane Mori, to whom this book is dedicated. It is divided into seven sections dedicated to the analysis of Guadinino compounds in the brain, free radicals and cell damage, the role of nitric oxide and neuronal disorders, the role of free radicals in the brain, the importance of free radicals in other neurological disorders, stress and environmental effects, and factors related to neurotoxicity. Several new approaches related to the prevention and treatment of free radical-related neurological disorders are well expanded by the contribution of multiple authors. The illustrations are pertinent. The index is appropriate for the content of the book. The overall appearance of the book is good. "I found this book to represent a nice review of the importance of free radicals in neurophysiology, and I highly recommend it for neuroscientists, neurologists, neurosurgeons, and neuropharmacologists.
Booknews
Papers from an August 1995 conference held in Tokyo detail recent research in the role of free radicals in neurodegeneration, highlighting the functions of nitric oxide in both normal and abnormal neuronal functioning, free radicals in brain disorders such as Parkinson's and epilepsy, new imaging technologies, and free radical involvement in stress and mental disorders. Includes sections on guanidino compounds in the brain, free radicals in cell damage, nitric oxide and neuronal disorders, and neurotoxicity. Annotation c. by Book News, Inc., Portland, Or.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780125434454
  • Publisher: Elsevier Science & Technology Books
  • Publication date: 1/28/1996
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 474
  • Product dimensions: 6.31 (w) x 9.29 (h) x 1.04 (d)

Table of Contents

Contributors
Preface
1 Reactive Oxygen Species and Mechanism of Induction of Seizure by Guanidino Compounds
2 Prevention of Free Radical Damage in the Brain: Protection by [alpha]-Lipoic Acid
3 Oxidative Cell Damage Induced by Radicals and Inhibited by Antioxidants
4 Active Oxygen Species in Neutrophil-Endothelial Cell Interactions
5 Oxygen Radicals in Glutamate Toxicity of C6 Glioma Cells via Transporter System
6 Neuroprotective and Neuropathologic Effects of Nitric Oxide: Role of N-Methyl-D-aspartate Receptor
7 Pathologic Roles of Nitric Oxide in the Central Nervous System
8 Subcellular Targeting of Neuronal Nitric Oxide Synthase
9 Cross-Talk between Superoxide and Nitric Oxide Radicals in Regulation of Neurovascular Network
10 Oxidative Stress and Transcription Factors
11 Zinc Metallothionein Isoforms in Free Radical-Mediated Striatal Damage in Parkinson's Disease
12 Abnormalities of Superoxide Dismutase Isoenzyme Pattern during Development and Formation of Abnormal Plasticity in Epileptic Mutant EL Mice Brain
13 Free Radicals and Posttraumatic Epilepsy: Induction and Limitation of Brain Injury Responses
14 Electron Spin Resonance-Computed Tomography: Brain Imaging and Epilepsy
15 Increase in Number of Mn- and Cu,Zn-Superoxide Dismutase-like Immunoreactive Cells after Injection of FeCl[subscript 3] into Rat Sensorimotor Cortex
16 Radical Scavengers as Preventive Preparations of Posttraumatic Epilepsy
17 [alpha]-Phenyl-tert-butylnitrone: Inhibition of Free Radical Formation and Release from Injured Brain
18 N,N'-Propylenedinicotinamide: Scavengers of Free Radicals and Inhibitor of Free Radical-Promoted Damages to Benzoate, Deoxyribose, and Amino Acids
19 Neuroprotective Effects of [alpha]-Lipoic Acid in Cultured Neurons and Rodent Models of Focal Cerebral Ischemia
20 Neuroprotection against Ischemic Injury through Inhibition of Glutamate Release: N-Type Calcium Channel Antagonist and Cu,Zn-Superoxide Dismutase
21 Free Radical Imaging during Ischemia in Rat Brain
22 Oxidative Stress and Protein Modification in Neurodegenerative Disease
23 Free Radicals and Superoxide Dismutase in Dementia
24 Mitochondrial Damage in Neurodegenerative Disease
25 Neuroprotection in Progressive Neurodegenerative Diseases of Alzheimer's and Parkinson's Types: Action of L-Deprenyl and Rasagiline
26 Clinical Evaluation of Free Radicals Identified by Electron Spin Resonance in Human Blood and Cerebrospinal Fluid
27 Free Radicals and Antioxidants in Pathophysiology of Mammalian Retina
28 Abnormal Cu,Zn-Superoxide Dismutase (SOD1) in Familial Amyotrophic Lateral Sclerosis with Two Base-Pair Deletion in SOD1 Gene
29 Lipid Peroxidation and Antioxidant Enzymes in Brain Regions after Immobilization Stress in August Rats: Correlation with Behavioral Patterns
30 Radiation Effects on in Vivo Redox Reaction in Brain of Living Mice
31 World Health Organization Research Activities in the Field of Neuroscience
32 Free Radicals and Neurodegenerative Diseases: Stress and Oxidative Damage
33 Nitric Oxide and Superoxide Radicals as Mediators of Toxicity of Amphetamine Analogs
34 Neurotoxicity and Lipid Peroxidation Induced by Trichloroethylene and Related Substances in Wistar Rat Brain
Index
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