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Free Radicals: A Practical Approach

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Free radicals are recognized as being of increasing importance in many aspects of normal cell metabolism and pathological processes. Studies in this area depend critically on techniques that allow detection and measurement of free radicals which have lifetimes in the order of microseconds. This book describes the latest methods for quantifying radicals and their effects, providing detailed protocols, hints and tips for success, troubleshooting comments, illustrative data, and key literature citations. This book ...
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Oxford, England 1996 Hard cover New in new dust jacket. Sewn binding. Cloth over boards. 336 p. Contains: Illustrations. Practical Approach Series, 168. Audience: General/trade.

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Overview

Free radicals are recognized as being of increasing importance in many aspects of normal cell metabolism and pathological processes. Studies in this area depend critically on techniques that allow detection and measurement of free radicals which have lifetimes in the order of microseconds. This book describes the latest methods for quantifying radicals and their effects, providing detailed protocols, hints and tips for success, troubleshooting comments, illustrative data, and key literature citations. This book is a unique laboratory manual of techniques for the direct and indirect measurement of both free radicals and the antioxidants that protect against them. All researchers who study free radicals will find this volume invaluable.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Gene A. Homandberg, PhD (Rush Medical College of Rush University)
Description: This manual from the Practical Approach series is a compilation of techniques in free radical research as contributed by 44 contributors from numerous disciplines. It covers physicochemical methods of free radical detection, biochemical methods of detection, measurement of free radical products, and measurements of antioxidants, including measurement of antioxidant gene expression.
Purpose: This manual is meant to provide detailed practical knowledge of fundamental as well as newer techniques to those new to free radical research. This is especially of value because of the rapid expansion of our knowledge of the role of free radicals in normal cell metabolism and human diseases. Although this is a methods book, it would have been useful to provide, as an introduction, a broader overview of known functions of free-radicals in cell metabolism, especially in terms of signal transduction.
Audience: The audience is meant to be primarily biochemists and secondarily molecular biologists and cell biologists.
Features: This book has the typical attractive and very easy-to-read format of the Practical Approach series. It features at least several abbreviated protocols within each chapter as well as a list of suppliers at the end of the book.
Assessment: This book is highly recommended for the institutional as well as personal library because of the ubiquitous nature of free radical research. A manual on methods was sorely needed in this area and this book will be very useful.
Gene A. Homandberg
This manual from the Practical Approach series is a compilation of techniques in free radical research as contributed by 44 contributors from numerous disciplines. It covers physicochemical methods of free radical detection, biochemical methods of detection, measurement of free radical products, and measurements of antioxidants, including measurement of antioxidant gene expression. This manual is meant to provide detailed practical knowledge of fundamental as well as newer techniques to those new to free radical research. This is especially of value because of the rapid expansion of our knowledge of the role of free radicals in normal cell metabolism and human diseases. Although this is a methods book, it would have been useful to provide, as an introduction, a broader overview of known functions of free-radicals in cell metabolism, especially in terms of signal transduction. The audience is meant to be primarily biochemists and secondarily molecular biologists and cell biologists. This book has the typical attractive and very easy-to-read format of the Practical Approach series. It features at least several abbreviated protocols within each chapter as well as a list of suppliers at the end of the book. This book is highly recommended for the institutional as well as personal library because of the ubiquitous nature of free radical research. A manual on methods was sorely needed in this area and this book will be very useful.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780199635603
  • Publisher: Oxford University Press, USA
  • Publication date: 11/28/1996
  • Series: Practical Approach Series
  • Edition number: 1
  • Pages: 336
  • Product dimensions: 6.31 (w) x 9.56 (h) x 0.83 (d)

Table of Contents

1. Introduction

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