From Genes to Genomes: Concepts and Applications of DNA Technology / Edition 3

From Genes to Genomes: Concepts and Applications of DNA Technology / Edition 3

by Jeremy W. Dale, Malcolm von Schantz, Nicholas Plant
     
 

Designed for a second-year graduate-level course in genetics, this text covers both traditional and novel techniques and concepts including polymerase chain reaction (PCR), DNA sequencing, and transgenics. The first half of the book introduces basic molecular biology, how to clone a gene, purification and separation of nucleic acids, cutting and joining DNA, vectors,… See more details below

Overview

Designed for a second-year graduate-level course in genetics, this text covers both traditional and novel techniques and concepts including polymerase chain reaction (PCR), DNA sequencing, and transgenics. The first half of the book introduces basic molecular biology, how to clone a gene, purification and separation of nucleic acids, cutting and joining DNA, vectors, and genomic and cDNA libraries. The second covers finding the right clone, PCR strategies and applications, principles and analysis of gene sequencing, genetic variation and expression, analysis of gene function, and present and future medical applications. Annotation ©2003 Book News, Inc., Portland, OR

Product Details

ISBN-13:
9780470683859
Publisher:
Wiley
Publication date:
02/14/2012
Edition description:
New Edition
Pages:
400
Sales rank:
908,998
Product dimensions:
6.60(w) x 9.50(h) x 0.80(d)

Table of Contents

Preface
1Introduction1
2Basic Molecular Biology5
3How to Clone a Gene21
4Purification and Separation of Nucleic Acids31
5Cutting and Joining DNA41
6Vectors65
7Genomic and cDNA Libraries99
8Finding the Right Clone121
9Polymerase Chain Reaction (PCR)143
10DNA Sequencing161
11Analysis of Sequence Data177
12Analysis of Genetic Variation209
13Analysis of Gene Expression227
14Analysis of Gene Function259
15Manipulating Gene Expression279
16Medical Applications, Present and Future307
17Transgenics325
Bibliography339
Glossary341
Index353

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