Functional MRI: An Introduction to Methods

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This book provides a comprehensive introduction to functional magnetic resonance imaging(fMRI), the scanning technique which allows the mapping of active processes within the brain. There are six sections to the book with chapters from an expert international team. Part I provides a broad overview of the field and sets the context. Part II describes the physiological and physical background to fMRI, including coverage of the hardware required and pulse sequence selection. Practical issues involving experimental design of the paradigms, psycho-physical stimulus delivery and subject response are covered in Part III, followed by a comprehensive treatment of data analysis in Part IV. Part V deals with practical applications of the technique in the field of neuroscience and in clinical practice. The final section describes how fMRI can be integrated with other neuro-electromagnetic functional maopping techniques. Functional Magnetic Resonance Imaging: An Introduction to Methods is written to be accessible to a wide-ranging audience of research scientists interested in studying how the normal brain works, and clinicians interested in monitoring disease states and processes.

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Editorial Reviews

From the Publisher

"...well written and should find a prominent place in the cubicles of aspiring and established fMRI researchers."--Nature Neuroscience, volume 5, no 5, May 2002

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Product Details

  • ISBN-13: 9780198527732
  • Publisher: Oxford University Press, USA
  • Publication date: 3/28/2003
  • Edition description: New Edition
  • Pages: 432
  • Product dimensions: 9.60 (w) x 7.40 (h) x 1.00 (d)

Table of Contents

Part I: Introduction
1. An introduction to FMRI of the brain, Matthews
Part II: Physics and Physiology
2. Brain energy metabolism and the physiological basis of the haemodynamic response, Gjedde
3. Principles of nuclear magnetic resonance and MRI, Jezzard & Clare
4. Ultra-fast MRI, Jones, Brookes & Moonen
5. Hardware for functional MRI, Glover
6. Selection of the optimal pulse sequence for functional MRI, Bandettini
7. Spatial and temporal resolution in fMRI, Menon & Goodyear
8. Quantitative measurement using fMRI, Hoge & Pike
Part III: Experimental Design
9. Effective paradig design, Donaldson & Buckner
10. The scanner as a psychophysical laboratory, Savoy
Part IV: Analysis of Functional Imaging Data
11. Overview of fMRI analysis, Smith
12. Preparing fMRI data for statistical analysis, Smith
13. Head motion and its correction, Brammer
14. Statistical analysis of activation images, Worsley
15. Registration, brain atlases and cortical flattening, Jenkinson & Smith
16. Extracting brain connectivity, Buchel & Friston
Part V: fMRI Applications
17. fMRI: applications in cognitive neuroscience, Owen, Epstein & Johnsrude
18. Clinical applications of mapping neurocognitive processes in the human brain with fMRI, Thulborn & Gisbert
Part VI: Integrating Technologies
19. Dynamic functional neuroimaging integrating multiple modalities, George, Schmidt, Rector & Wood

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