Functional Neural Transplantation III: Primary and Stem Cell Therapies for Brain Repair, Part I

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Overview

This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

Leading authors review the state-of-the-art in their field of investigation, and provide their views and ...

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Functional Neural Transplantation III: Primary and Stem Cell Therapies for Brain Repair, Part I

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More About This Book

Overview

This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

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Product Details

  • ISBN-13: 9780444595751
  • Publisher: Elsevier Science
  • Publication date: 1/4/2013
  • Pages: 448
  • Product dimensions: 7.60 (w) x 9.30 (h) x 1.00 (d)

Table of Contents

  1. Preface

  2. Stephen Dunnett and Anders Björklund

  3. Transplantation in the Future

  4. Fred H. Gage

  5. Ethical Challenges for Using Human Cells in Clinical Cell Therapy

  6. Göran Hermerén

  7. Banking Stem Cells for Research and Clinical Applications

  8. Glyn Stacey

  9. Survival, Differentiation and Connectivity of Ventral Mesencephalic Dopamine Neurons following Transplantation

  10. Lachlan Thompson and Anders Björklund

  11. Electrophysiological Investigations of Synaptic Connectivity between Host and Graft Neurons

  12. Jan Tønnesen and Merab Kokaia

  13. Nigral Grafts in Animal Models of Parkinson’s Disease. Is Recovery beyond Motor Function Possible?

  14. Mariah J. Lelos, Eilís Dowd and Stephen B. Dunnett

  15. L-DOPA- and Graft-Induced Dyskinesia following Transplantation

  16. Emma L. Lane and Christian Winkler

  17. Current Status of Clinical Trials of Neural Transplantation in Parkinson’s Disease

  18. Jonathan R Evans, Sarah L Mason and Roger A Barker

  19. In vivo Imaging of the Integration and Function of Nigral Grafts in Clinical Trials

  20. Marios Politis and Paola Piccini

  21. Neuropathology in Transplants in Parkinson’s Disease: Implications for Disease Pathogenesis and the Future of Cell Therapy

  22. Patrik Brundin and Jeffrey H. Kordower

  23. Derivation of Dopaminergic Neurons from Pluripotent Stem Cells

  24. Lorenz Studer

  25. Characterization and Criteria of Embryonic Stem and Induced Pluripotent Stem Cells for a Dopamine Replacement Therapy

  26. Oliver Cooper, Malin Parmar and Ole Isacson

  27. Skilled Motor Control for the Preclinical Assessment of Functional Deficits and Recovery following Nigral and Striatal Cell Transplantation

  28. Alexander Klein and Ian Q. Whishaw

  29. Role of Experience, Training and Plasticity in the Functional Efficacy of Striatal Transplants

  30. Máté D. Döbrössy and Guido Nikkhah

  31. In vivo Imaging of Integration and Function of Striatal Grafts in Rodent and Non-Human Primate Animal Models

  32. Philippe Hantraye and Romina Aron Badin

  33. Clinical Trials of Neural Transplantation in Huntington’s Disease

  34. Anne E. Rosser and Anne-Catherine Bachoud-Lévi

  35. Derivation of Striatal Neurons from Human Stem Cells Pedro Viegas, Camille Nicoleau and Anselme L. Perrier
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