Functional Synthetic Receptors / Edition 1

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A timely overview of this rapidly-expanding topic, covering the most important classes of compounds and incorporating the latest literature. With its application-oriented approach, this book is the first to emphasize current and potential applications, extending to such fields as materials science, bioorganic chemistry, medicinal chemistry, and organic synthesis. In the biological context in particular, the book clarifies which receptor systems work well in water or better under physiological conditions.
From the contents:
* Amino Acid, Peptid and Protein Receptors
* Carbohydrate Receptors
* Ammonium, Amidinium and Guanidinium Receptors
* Anion Receptors
* Molecular Capsules and Self Assembly
* Dynamic Combinatorial Libraries based on Molecular Recognition
* Molecular Machines
* Self-Replication
Aimed at graduate students and specialists in the field, this is also of interest to pharmaceutical companies involved in drug design, as well as chemical companies with a polymer or nanotechnology group. In addition, analytical companies working on the advanced equipment covered here will find stimulating new applications.

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Product Details

  • ISBN-13: 9783527306558
  • Publisher: Wiley
  • Publication date: 4/22/2005
  • Edition number: 1
  • Pages: 440
  • Product dimensions: 6.99 (w) x 9.76 (h) x 1.03 (d)

Meet the Author

Thomas Schrader is Professor of Organic Chemistry at the Universityof Marburg. He studied chemistry and obtained his PhD in 1988 underW. Steglich at the Friedrich-Wilhelms-University of Bonn. After apostdoctorate stay at Princeton University under E.C. Taylor ontotal synthesis of antitumor agents, he gained his lecturingqualification at the University of Düsseldorf. In 2000 hejoined the University of Marburg as associate professor. Hisresearch focuses on bioorganic aspects of supramolecular systems,optimizing and multiplying new binding motifs for characteristicstructural features in biomolecules - a concept that leads toartificial receptor molecules capable of specifically interferingwith biological processes. Applications include biosensors, drugscountering protein misfolding and tweezers for protein assembly.Professor Schrader is the holder of the Bredereck-symposium prizein bioorganic chemistry (2001).

Andrew D. Hamilton received his PhD from Cambridge University in1980, and the following year carried out his postdoc research atUniversité Louis Pasteur, Strasbourg. Between 1981 and 1988 hewas Assistant Professor for Chemistry at Princeton University,thereafter Associate Professor until 1992, when he became FullProfessor at the University of Pittsburgh, a post he held until1997. Since 1997 he has been Irénée duPont Professor ofChemistry and, since 1998, Professor of Molecular Biophysics andBiochemistry at Yale University. Here he held the Chair of theChemistry Department between 1999 and 2003, and has been DeputyProvost for Science and Technology since 2003. Professor Hamiltonlectures at several universities in the USA.

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Table of Contents

Amino Acid, Peptid and Protein Receptors
Carbohydrate Receptors
Ammonium, Amidinium and Guanidinium Receptors
Anion Receptors
Molecular Capsules and Self Assembly
Dynamic Combinatorial Libraries based on MolecularRecognition
Molecular Machines

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