Fundamental Neuroscience / Edition 4

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The fourth edition of Fundamental Neuroscience reinvents itself as an engrossing and comprehensive presentation of the discipline of neuroscience, from molecules to cognition. Thorough but succinct, and lavishly illustrated, the book builds from an introductory section that includes fundamental neuroanatomy and goes on to cover cellular and molecular neuroscience, development, sensory systems, motor systems, regulatory systems, and behavioral and cognitive neuroscience. The book has been retooled to better serve its audience in the neuroscience and medical communities.

The chapters include more than 100 boxes describing clinical conditions, techniques, and other special topics. Each chapter went through a thorough review process, giving the book an evenness of tone. The chapters are authored by outstanding working scientists who are experts on the topics they cover.

  • Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries
  • 30% new material including new chapters on dendritic development and spine morphogenesis, chemical senses, cerebellum, eye movements, circadian timing, sleep and dreaming, and consciousness
  • Accompanying website for students and instructors
  • Additional text boxes describing key experiments, disorders, methods, and concepts
  • More than 650 four-color illustrations, micrographs, and neuroimages
  • Multiple model system coverage beyond rats, mice, and monkeys
  • Extensively expanded index for easier referencing

Audience: Graduate students and researchers in neuroscience, as well as medical students.

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Editorial Reviews

From the Publisher
"Here in the fourth edition of this textbook, editors Squire, Berg, Bloom, du Lac, Ghosh, and Spitzer, all working scientists with backgrounds in various specialties in neuroscience, present extensive new material with all chapters updated and rewritten. The book is organized into seven sections with numerous chapters in each encompassing a comprehensive view of 21st century neuroscience…"—Reference & Research Book News, December 2013
Doody's Review Service
Reviewer: Michael Joel Schrift, DO, MA (University of Illinois at Chicago College of Medicine)
Description: Neuroscience is a rapidly evolving field and this book is an excellent introduction to this exciting discipline for students in multiple fields. Written and edited by a group of internationally recognized neuroscientists, the third edition remains a superb and comprehensive reference and textbook, just as the previous two editions were.
Purpose: The purpose, according to the editors, is "to capture the promise and excitement of this fast moving field." They note that due to advances in such fields as genetics and neuroimaging, the chapters required revision from the previous edition to "effectively introduce(s) students to the full range of contemporary neuroscience."
Audience: The intended audience includes students, clinicians, and neuroscientists.
Features: Part I focuses on the basics/fundamentals of neuroscience with chapters on such topics as cellular organization, history of the field, and responsible research conduct. In part II, cellular and molecular mechanisms are reviewed from the subcellular level up to complex information processing. Nervous system development is reviewed in part III with chapters on cellular determinism, neurogenesis and migration, programmed cell death, synaptic elimination, and early experience driven neuroplasticity and sensitive periods. Parts IV and V cover the sensory and motor systems respectfully. Part VI focuses on the regulatory systems with chapters on the hypothalamus, organization of the autonomic nervous system, respiratory and cardiovascular systems, homeostasis, neuroendocrine control, circadian timekeeping, sleep, and reward systems. Part VII covers the behavioral and cognitive neurosciences with outstanding chapters on evolution, aging, visual object perception, spatial cognition, attention, learning and memory, language, executive functions, and consciousness. Each chapter concludes with relevant citations of the scientific literature and the index was useful.
Assessment: This is essential reading for any student of neuroscience. Every issue pertinent to the study of the brain and behavior is covered in this excellent book.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780123858702
  • Publisher: Elsevier Science
  • Publication date: 11/26/2012
  • Edition description: New Edition
  • Edition number: 4
  • Pages: 1152
  • Sales rank: 478,872
  • Product dimensions: 8.80 (w) x 11.00 (h) x 1.70 (d)

Meet the Author

Larry R. Squire is Distinguished Professor of Psychiatry, Neurosciences, and Psychology at the University of California, San Diego. He is also a Research Career Scientist at the Veterans Affairs Medical Center in San Diego. Squire is a member of the National Academy of Sciences and a past president of the Society for Neuroscience.

Floyd Bloom was the editor of Science magazine, now Brain Research.

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Table of Contents

Section I: Neuroscience - Fundamentals of Neuroscience / Basic Plan of the Nervous System

Section II: Cellular and Molecular Neuroscience - Cellular Components of Nervous Tissue / Subcellular Organization of the Nervous System: Organelles and Their Functions / Membrane Potential and Action Potential / Neurotransmitters / Release of Neurotransmitters / Neurotransmitter Receptors / Intracellular Signaling / Postsynaptic Potentials and Synaptic Integration / Information Processing in Dendrites / Brain Energy Metabolism

Section III: Nervous System Development - Neural Induction and Pattern Formation / Cellular Determination / Neurogenesis and Migration / Growth Cones and Axon Pathfinding / Synapse Formation / Programmed Cell Death and Neurotrophic Factors / Synapse Elimination / Dendritic Development / Experience-dependent Plasticity

Section IV: Sensory Systems - Fundamentals of Sensory Systems / Chemical Senses: Taste and Olfaction / The Somatosensory System / Audition / Vision

Section V: Motor Systems - Fundamentals of Motor Systems / The Spinal and Peripheral Motor System / Descending Control of Movement / The Basal Ganglia / Cerebellum / Eye Movements

Section VI: Regulatory Systems - The Hypothalamus: An Overview of Regulatory Systems / Central Control of Autonomic Functions: Organization of the Autonomic Nervous System / Neural Control of Breathing / Food Intake and Metabolism / Water Intake and Body Fluids / Neuroendocrine Systems / Circadian Timekeeping / Sleep, Dreaming, and Wakefulness / Reward, Motivation, and Addiction

Section VII: Behavioral and Cognitive Neuroscience - Human Brain Evolution / Cognitive Development and Aging / Visual Perception of Objects / Spatial Cognition / Attention / Learning and Memory: Basic Mechanisms / Learning and Memory: Brain Systems / Language and Communication / The Prefrontal Cortex and Executive Brain Functions / Consciousness

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