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Doody's Review ServiceReviewer: Sophie La Salle, PhD (Midwestern University Chicago College of Osteopathic Medicine)
Description: This book offers a broad, in-depth foundation of basic biochemical concepts by anchoring the biological content in its chemistry roots. This edition has been updated with the latest findings in biochemistry and their connection to human health, artwork to provide a clearer learning experience, and approaches to favor active learning. The previous edition was published in 2008.
Purpose: It serves many purposes, including delivering a solid foundation in modern biochemistry, developing problem-solving skills, and providing the historical background behind important biochemical discoveries. It is a complete guide to foundational biochemistry.
Audience: Although written for health sciences undergraduate and graduate students, the book may be used by premedical, medical, and other healthcare graduate students as a thorough reference. The authors are highly regarded educators, researchers, and teachers.
Features: Five major sections - an introduction, biomolecules, enzymes, metabolism and gene expression and replication — cover topics in modern biochemistry in the context of their chemical basis to help students understand the molecular foundation of biochemical reactions. In light of recent research findings, there is an emphasis on human health and diseases as well as novel pharmacological effectors. The book is well organized and beautifully illustrated, the artwork has been extensively revised, and process diagrams are clearly identified. It is enhanced with features that promote learning and self-assessment. For example, it includes "Key Concepts," reviews chemical principles when appropriate, provides sample calculations, contains "Checkpoint Questions" at the end of every section, and presents new end-of-chapter problems. It also contains a helpful glossary and a detailed index. The book is designed to provide a strong foundation in biochemistry by fostering student understanding rather than memorization.
Assessment: This is a magnificent textbook on biochemistry principles. (Readers looking for a quick review are advised to choose another book.) This edition includes up-to-date information and favors active learning by expanding its pedagogical tools and approaches. This book is of comparable caliber and coverage as Lehninger Principles of Biochemistry, 6th edition, Nelson and Cox, (W.H. Freeman, 2013). Students will certainly acquire a solid basis in biochemistry with this textbook.