Fundamentals of Biochemistry: Life at the Molecular Level / Edition 3

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Overview

Voet, Voet, and Pratt's Fundamentals of Biochemistry, challenges students to better understand the chemistry behind the biological structure and reactions occurring in living systems. The Third Edition continues this tradition, and additionally incorporates coverage of recent research and an expanded focus on preparing and supporting students throughout the course. With the addition of new conceptual assessment content to WileyPLUS (access to WileyPLUS not included), students have the opportunity to assess their conceptual understanding of key introductory biochemistry concepts and retrain themselves on their misconceptions.
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Product Details

  • ISBN-13: 9780470228425
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 5/2/2008
  • Edition description: Student
  • Edition number: 3
  • Pages: 360
  • Product dimensions: 8.60 (w) x 10.91 (h) x 0.79 (d)

Meet the Author

Donald Voet received a B.S. in Chemistry from the California Institute of Technology, a Ph.D. in Chemistry from Harvard University with William Lipscomb, and did postdoctoral research in the Biology Department at MIT with Alexander Rich. Upon completion of his postdoctoral research, Don took up a faculty position in the Chemistry Department at the University of Pennsylvania where, for the past 38 years, he has taught a variety of Biochemistry courses as well as general Chemistry. His major area of research is the X-ray crystallography of molecules of biological interest. He has been a visiting scholar at Oxford University, The University of California at San Diego, and the Weizmann Institute of Science in Israel. Together with Judith G. Voet, he is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education. He is a member of the Education Committee of the International Union of Biochemistry and Molecular Biology. His hobbies include backpacking, scuba diving, skiing, travel, photography, and writing Biochemistry textbooks.

Judith ("Judy") Voet received her B.S. in Chemistry from Antioch College and her Ph.D. in Biochemistry from Brandeis University with Robert H. Abeles. She has done postdoctoral research at the University of Pennsylvania, Haverford College, and the Fox Chase Cancer Center. Her main area of research involves enzyme reaction mechanisms and inhibition. She taught Biochemistry at the University of Delaware before moving to Swarthmore College. She taught there for 26 years, reaching the position of James H. Hammons Professor of Chemistry and Biochemistry before going on "permanent sabbatical leave." She has been a visiting scholar atOxford University, University of California, San Diego, University of Pennsylvania, and the Weizmann Institute of Science, Israel. She is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education. She has been a member of the Education and Professional Development Committee of the American Society for Biochemistry and Molecular Biology as well as the Education Committee of the International Union of Biochemistry and Molecular Biology. Her hobbies include hiking, backpacking, scuba diving, and tap dancing.

Charlotte Pratt received her B.S. in Biology from the University of Notre Dame and her Ph.D. in Biochemistry from Duke University under the direction of Salvatore Pizzo. Although she originally intended to be a marine biologist, she discovered that Biochemistry offered the most compelling answers to many questions about biological structure-function relationships and the molecular basis for human health and disease. She conducted postdoctoral researching the Center for Thrombosis and Hemostasis at the University of North Carolina at Chapel Hill. She has taught at the University of Washington and currently teaches at Seattle Pacific University. In addition to working as an editor of several Biochemistry textbooks, she has co-authored Essential Biochemistry and previous editions of Fundamentals of Biochemistry.

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Table of Contents

Ch. 1 Introduction to the chemistry of life 2
Ch. 2 Water 22
Ch. 3 Nucleotides, nucleic acids, and genetic information 40
Ch. 4 Amino acids 76
Ch. 5 Proteins : primary structure 94
Ch. 6 Proteins : three-dimensional structure 129
Ch. 7 Protein function : myoglobin and hemoglobin 181
Ch. 8 Carbohydrates 206
Ch. 9 Lipids and biological membranes 233
Ch. 10 Membrane transport 284
Ch. 11 Enzymatic catalysis 312
Ch. 12 Enzyme kinetics, inhibition, and regulation 357
Ch. 13 Introduction to metabolism 395
Ch. 14 Glucose catabolism 427
Ch. 15 Glycogen metabolism and gluconeogenesis 472
Ch. 16 Citric acid cycle 514
Ch. 17 Electron transport and oxidative phosphorylation 545
Ch. 18 Photosynthesis 590
Ch. 19 Lipid metabolism 627
Ch. 20 Amino acid metabolism 682
Ch. 21 Mammalian fuel metabolism : integration and regulation 743
Ch. 22 Nucleotide metabolism 787
Ch. 23 Nucleic acid structure 817
Ch. 24 DNA replication, repair, and recombination 867
Ch. 25 Transcription and RNA processing 919
Ch. 26 Translation 960
Ch. 27 Regulation of gene expression 1010
Ch. 28 Protein function part II : cytoskeletal and motor proteins and antibodies 1072
App Bioinformatics exercises 1115
App Answers to bioinformatics exercises 1124
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