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Doody's Review ServiceReviewer: Bhavesh Barad, MD (East Tennessee State University Quillen College of Medicine)
Description: This is a single-author reference on evidence-based practice and translational science by a well-recognized author in the field.
Purpose: The book details the tools required for comparative effectiveness research, as well as the methods particularly useful for systematic evaluation of statistical analysis and meta-analysis.
Audience: The intended audience includes clinical investigators, medical practitioners, and students and teachers in medical sciences (especially dentistry), clinical/basic research, statistics, epidemiology, and biostatistics.
Features: The initial part focuses on explaining evidence-based decision making and covers research synthesis characteristics and their usefulness with systematic review and meta-analysis. The second part explains in detail various tools of evidence-based research, with a comprehensive discussion of data analysis, power, inferences, and validity or prediction. The book is written in a way to make the subject easier to understand. Chapters explain concepts in a logical fashion, with step-by-step analysis as well as examples and schematics. A brief summary begins each chapter to highlight core concepts. Both the theory and step-by-step analysis of each concept are explained with examples to benefit even nonclinical and nonresearch readers. The additional references at the end provide a thorough database for additional learning.
Assessment: This book is excellent. It is a valuable resource for gaining a basic understanding of evidence-based research and translational science and its practical application that can be used as a reference by students and teachers of epidemiology, statistics, and biostatistics, as well as medical science and clinical investigators.