Fundamentals of Medicinal Chemistry / Edition 1

Paperback (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $22.15
Usually ships in 1-2 business days
(Save 58%)
Other sellers (Paperback)
  • All (11) from $22.15   
  • New (6) from $42.73   
  • Used (5) from $22.15   

Overview

Fundamentals of Medicinal Chemistry is a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style. Opening with a review of the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms, the text then covers the discovery and design of drugs, pharmacokinetics and drug metabolism. The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing of the final product. The text assumes little in the way of prior biological knowledge and only a basic chemical knowledge. Relevant biology is included through biological topics, examples and in the Appendices.
Read More Show Less

Editorial Reviews

From the Publisher

"…it would be of great value to beginning graduate students in medicinal chemistry…it should be included in any practicing chemist's personal library." (Journal of Medicinal Chemistry, July 29, 2004)

"Thomas presents the fundamentals of medicinal chemistry in a clear, concise, and descriptive fashion.” (Choice, June 2004, Vol. 41 No. 10)

"...provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style..." (www.organische-chemie.ch, 19/01/2004)

“…well laid out, with an attractive typeface.” (Chemistry and Industry, 6th September 2004)

Read More Show Less

Product Details

  • ISBN-13: 9780470843079
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 12/1/2003
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 302
  • Sales rank: 1,219,414
  • Product dimensions: 7.50 (w) x 9.80 (h) x 0.70 (d)

Table of Contents

Preface
Acknowledgements
Abbreviations/Acronyms
1 Biological Molecules 1
2 An Introduction to Drugs and their Action 37
3 An Introduction to Drug Discovery 57
4 The SAR and QSAR Approaches to Drug Design 71
5 Computer Aided Drug Design 95
6 Combinatorial Chemistry 113
7 Selected Examples of Drug Action at some Common Target Areas 131
8 Pharmacokinetics 159
9 Drug Metabolism 181
10 An Introduction to Lead and Analogue Syntheses 203
11 Drug Development and Production 223
Appendix 239
Answers to Questions 261
Selected Further Reading 273
Index 275
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)