Fundamentals of Osteoporosis
552Fundamentals of Osteoporosis
552eBook
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Overview
Fundamentals of Osteoporosis offers a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work. Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, and histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery.
- Presents a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work
- Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery
- Clear, concise presentations by bone biologists of the cellular and molecular mechanisms underlying osteoporosis
Product Details
ISBN-13: | 9780123751089 |
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Publisher: | Elsevier Science |
Publication date: | 09/24/2009 |
Sold by: | Barnes & Noble |
Format: | eBook |
Pages: | 552 |
File size: | 5 MB |
About the Author
David Feldman, MD, is Emeritus Professor of Medicine (Active) at Stanford University School of Medicine where he has been on the faculty since 1974. He has been a full professor since 1984 and was chief of the Endocrinology Division for 10 years. His laboratory studies the role of steroid hormone receptors, particularly the vitamin D receptor, and its mechanism of action. His current major research focus is hormone-dependent cancer including breast cancer and prostate cancer and the pathways by which vitamin D inhibits cancer growth. Professor Feldman is actively involved in both basic science approaches to the anti-cancer actions of vitamin D as well as to clinical trials studying the use of vitamin D in breast and prostate cancer. Professor Feldman was recently honored with an award for a Career of Outstanding Contributions to Vitamin D Research. He has authored over 290 medical research articles, reviews, editorials, and book chapters. In addition to being a co-editor of all four editions of OSTEOPOROSIS, he is the editor-in-chief of Vitamin D, just published in its third edition.
Dr. Rosen is Professor and Senior Scientists at The Jackson Laboratory, Bar Harbor, Maine, where his group studies the role of insulin-like growth factors on bone and the genetics of osteoporosis in inbred strains of mice. In 2007 he joined the Maine Medical Center Research Institute in Scarborough, Maine. He is also the former Director of the Maine Center for Osteoporosis Research and Education, St. Joseph Hospital, Bangor.
Dr. Rosen is a Past President of the American Society of Bone and Mineral Research (ASBMR). He served five years as the First Editor in Chief of the Journal of Clinical Densitometry, the official journal for the International Society of Clinical Densitometry, and currently serves as Associate Editor of the Journal of Bone and Mineral Research. His publications exceed 270 manuscripts published in a wide spectrum of clinical and basic science journals.
Table of Contents
1. The Bone Organ System: Form and Function2. The Nature of Osteoporosis3. Skeletal Heterogeneity and the Purposes of Bone Remodeling4. Osteoblast Biology5. Osteoclast Biology6. Osteocytes7. The Regulatory Role of Matrix Proteins in Mineralization of Bone8. Development of the Skeleton9. Mouse Genetics as a Tool to Study Bone Development and Physiology10. Parathyroid Hormone and Parathyroid Hormone-Related Protein11. Vitamin D: Biology, Action, and Clinical Implications12. Regulation of Bone Cell Function by Estrogens13. Androgens and Skeletal Biology: Basic Mechanisms. Phosphatonins14. Wnt Signaling in Bone15. Cytokines and Bone Remodeling16. Skeletal Growth Factors17. Intercellular Communication during Bone Remodeling
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Presents a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work