Neonatology: Questions and Controversies Series: Gastroenterology and Nutrition

by Josef Neu

Overview

This exciting new reference brings you information about the most controversial gastroenterology and nutrition challenges you face in your practice. The book confidently tackles these subjects and gives seasoned advice on the latest diagnostic and treatment strategies using evidence-based medicine wherever possible. It gives you the latest information you need to keep pace with the fast-paced, dynamic environment of neonatology.

• Addresses controversial topics head on, so you can decide how to handle these difficult practice issues.
  
• Serves as the bridge between the latest cutting-edge research and its application to clinical practice.
  
• Assembles a world-class group of neonatologists, representing the true leaders of the specialty, to ensure the most authoritative content available.

Product Details

ISBN-13:	9781437721089
Publisher:	Elsevier Health Sciences
Publication date:	04/09/2008
Series:	Neonatology: Questions & Controversies
Sold by:	Barnes & Noble
Format:	eBook
Pages:	384
File size:	7 MB

About the Author

Dr. Neu is Professor, Department of Pediatrics, Division of Neonatology; he received his Bachelor of Arts Degree in 1971, at Wisconsin State University, Whitewater, WI. In 1975 he received his Medical Doctorate, University of Wisconsin, Madison, WI. Dr. Neu completed his Pediatrics Residency at John Hopkins Hospital, Baltimore, MD from 1975-1978, 1978-1980 Postdoctoral Fellow in Neonatology, Stanford University Medical Center, Stanford, CA. In 1987 he completed his Sabbatical, Inselspital, at the University of Bern, Switzerland. Dr. Neu has received during his career several honors and awards. He Chairs and is involved on National and International Committees. Dr. Neu is active on several Society Membership, Editorial boards, journal reviewer, Service to the Community, Service to schools. He is well known for his lectures here and aboard. Dr. Neu has received many appointments as Assistant Professor, Director, Division of Neonatology, Milwaukee Children’s Hospital Milwaukee, WI, Associate Professor, and Associate Division Chief for Neonatology, College of Medicine, University of Florida, Director/Neonatology Fellowship Program and Director of Neonatal Intensive Care Unit.

Table of Contents

Section 1: Scientific Overview and Developmental Perspectives

1.Gastrointestinal Development: Morphogenesis and Molecular Mechanisms

Robert Montgomery, PhD

2. Deitary Regulation of Gene Expression

Ian Sanderson, MD

3. The Exocrine Pancreas

Steven Werlin, MD
Alan Mayer, MD PhD

4. Innate Immunity and Epithelial Biology: Special Considerations in the Neonatal Gut

Patricia Lin, MD
Andrew S. Neish

5. The intestinal Microbiota and the Microbiome

Erika Claud, MD
W. Allan Walker, MD

6. Intestinal Barrier Function: Implications For the Neonate and Beyond

Ricardo Caicedo, MD
Martha Douglas-Escobar, MD
Nan Li, MD
Josef Neu, MD

7. Intestine as a Neuroendocrine organ

Carol Lynn Berseth, MD

8. Trophic Factors In the Neonatal Gastrointestinal Tract

Douglas G Burrin, PhD
Michael Janeczko, MD

9. Cholestasis in Neonates and Infants

Michael K. Davis, MD
Joel M. Andres, MD

Section 2: Nutrition

10. Regulation of Protein Synthesis and Proteolysis in the Neonate by Feeding
Tracy Gautsch Anthony, PhD
Susan Hazels Mitmesser, PhD

11. Non-Invasive Techniques to Monitor Nutrition in Neonates

Dominique Darmaun , MD
Jean-Christophe Rozé , MD

12. Nutritional Requirements of the Very Low Birthweight Infant

Patti J. Thureen, MD
William W. Hay, Jr., MD

13. Controversies in Neonatal Nutrition: Macro and Micronutrients
Frank R. Greer, MD

14. Diverse Roles of Lipids in Neonatal Physiology and Development

Nancy Auestad, PhD

Section 3: Select Clinical Entities

15. Necrotizing Enterocolitis: Pathogenesis, Clinical Care and Prevention
Josef Neu, M.D.
Martha Douglas-Escobar, M.D.

16. Short Bowel Syndrome

J. Marc Rhoads, MD

17. Adult Consequences of Neonatal and Fetal Nutrition: Mechanisms

Robert Lane, M.D.,
Clotilde desRobert
Kjersti Aagaard-Tillery,
Nichole Mitchell

18. Short Bowel Syndrome and Intestinal Tissue Engineering

Mike K. Chen, MD

Editorial Reviews

Reviewer: Jay P. Goldsmith, MD (Tulane University School of Medicine)
Description: This book, part of the Neonatology Questions and Controversies Series, reviews mostly the developmental biology of the gastrointestinal system. It is highly research based, although the final section deals with four selected clinical entities.
Purpose: The purpose is to emphasize the importance of nutrition in the treatment of critically ill neonates and provide up-to-date research to better understand the developmental biology of the gastrointestinal tract, nutritional needs of the premature infant, and the effects on later health and disease. These are worthy objectives and for the most part, the book meets them, although the emphasis is on research and developmental biology rather than clinical care in the neonatal period.
Audience: It is intended for neonatologists, pediatric gastroenterologists, and trainees in this field. It is probably too research oriented to appeal to students, nurses, and general practitioners.
Features: The three sections include a scientific overview and developmental perspectives, nutrition, and selected clinical entities. Each of the 18 chapters covers a different topic and is written by an expert in the field. The clinical entities include necrotizing enterocolitis, short bowel syndrome, and adult consequences of fetal and neonatal nutrition. Excellent reviews in the earlier sections cover neonatal cholestasis and nutritional requirements of the very low birth weight infant. Other clinical topics have been omitted or incorporated into other chapters. The illustrations are sparse and radiographs in the chapter on necrotizing enterocolitis are too small to be useful.
Assessment: This very well done review is heavily focused on developmental biology. Although some of the book hews to the clinical theme of the series, it is focused primarily on research questions and their effects on clinical practice and outcomes. Clinicians looking for guidance in the everyday practice of neonatology should instead use Neonatal Nutrition and Metabolism, 2nd edition, Thureen and Hay (Cambridge University Press, 2006). However, specialists wanting full discussions on specific developmental biology and gastrointestinal issues will find this a superb reference.

Doody's Review Service