Genes, Chromosomes, and Disease: From Simple Traits, to Complex Traits, to Personalized Medicine

Genes, Chromosomes, and Disease: From Simple Traits, to Complex Traits, to Personalized Medicine

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by Nicholas Wright Gillham
     
 

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This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable

Overview

This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

Editorial Reviews

Library Journal
This history of medical genetics with background on risk factors and disease and susceptibility genes is important for understanding complex polygenic diseases including cancer. Gillham (biology, emeritus, Duke Univ.) also tackles thorny issues of eugenics, IQ, and behavioral genetics. He covers current and emerging genetic testing, how genetic counseling was defined and has developed, and the rapidly expanding field of newborn genetic screening. In vitro fertilization, preimplantation genetic diagnostics (PGD), gene therapy, and stem cell therapeutics are also considered. VERDICT There are many less technical genetics books aimed at nonspecialists, but there are few, if any, simple answers to these complex questions. Gillham does a good job of explaining why we should care about history and specifics. Newly diagnosed patients, those in good health who worry, prospective parents, and parents of newly diagnosed newborns may well find these details and context just what they want. Recommended for collections with Stephen Jay Gould's The Mismeasure of Man, Kevin Davies's The $1,000 Genome, or related titles.—Mary Chitty, Cambridge Healthtech Lib., Needham, MA

Product Details

ISBN-13:
9780132623247
Publisher:
Pearson Education
Publication date:
03/15/2011
Series:
FT Press Science
Sold by:
Barnes & Noble
Format:
NOOK Book
Pages:
352
Sales rank:
877,340
File size:
2 MB

Related Subjects

Meet the Author

Nicholas Wright Gillham is James B. Duke Professor of Biology Emeritus. His research interests involved the genetics and molecular biology of cellular organelles called chloroplasts and mitochondria. For more than a decade he taught a course entitled “The Social Implications of Genetics.” This course fostered his interest in eugenics, human genetics, and their history. He has authored two books on chloroplasts and mitochondria plus a biography of the Victorian scientist Francis Galton entitled, A Life of Sir Francis Galton: From African Exploration to the Birth of Eugenics (Oxford University Press, 2001).

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Genes, Chromosomes, and Disease: From Simple Traits, to Complex Traits, to Personalized Medicine 4 out of 5 based on 0 ratings. 2 reviews.
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