Genetic Studies in Affective Disorders: Overview of Basic Methods, Current Directions, and Critical Research Issues

Overview

The search for causation in depression and other mood disorders has centered more and more on genetic predisposition and weakness. This outstanding text examines the current state of knowledge regarding genetics and affective illness. Deals with research findings, procedures and strategies.
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Overview

The search for causation in depression and other mood disorders has centered more and more on genetic predisposition and weakness. This outstanding text examines the current state of knowledge regarding genetics and affective illness. Deals with research findings, procedures and strategies.
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Editorial Reviews

Booknews
Presents recent trends and research concerning genetic epidemiology, diagnostic issues in pedigree assessment, and genetic linkage and molecular genetic studies. Clinical aspects include the family psychoeducational approach and genetic counseling issues in affective disorders among the orthodox Jewish community. The two final studies focus on animal models in the study of genetic factors in human psychopathology and lithium's effect on gene expression. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780471000754
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 2/3/1994
  • Series: Einstein Psychiatry Publication Series , #8
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 236
  • Product dimensions: 6.32 (w) x 9.27 (h) x 0.90 (d)

Table of Contents

Introduction
1 Genetic Epidemiology of Mood Disorders 3
2 Diagnostic Issues in Pedigree Assessment 28
3 Basic Principles in Linkage Analysis 46
4 An Epidemiologic and Genetic Study of Affective Disorders among the Old Order Amish 70
5 Genetic Linkage Studies in Psychiatry: Strengths and Weaknesses 91
6 Molecular Genetic Studies in Affective Illness 105
7 The Family Psychoeducational Approach: Rationale for a Multigenerational Treatment Modality for the Major Affective Disorders 119
8 Genetic Counseling Issues in Affective Disorders: The Orthodox Jewish Community 146
9 Animal Models in the Study of Genetic Factors in Human Psychopathology 177
10 Lithium's Effect on Gene Expression: Implications for the Pathogenesis of Mood Disorders 193
Author Index 219
Subject Index 230
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