Genetics: From Genes to Genomes / Edition 4

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Overview

The authors have developed a text that reflects the directions Genetics is taking as it heads into the 21st century. This perspective embraces five major themes: 1. the central importance of the genome,as opposed to the action of individual genes; 2. the application of genetics to the improvement of human health; 3. the growing appreciation for the relationships among organisms arising from genetic research; 4. the impact of biotechnology on the accelerating growth of genetic knowledge; and 5. the importance of emerging social and ethical issues related to our use of biotechnology.
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Product Details

  • ISBN-13: 9780073525266
  • Publisher: McGraw-Hill Higher Education
  • Publication date: 9/14/2010
  • Edition description: New Edition
  • Edition number: 4
  • Pages: 816
  • Sales rank: 193,995
  • Product dimensions: 8.70 (w) x 11.00 (h) x 1.30 (d)

Meet the Author

Dr. Hartwell received his Ph.D from MIT. He has held Assistant and Associate Professorships at the University of California before joining the faculty of the University of Washington, where he continues as a Full Professor. In 1996, Dr. Hartwell joined the Fred Hutchinson Cancer Research Center as a Full Member and Senior Advisor for Scientific Affairs, and was named President and Director of the Center in July, 1997.

Dr. Hartwell has received numerous awards and honors in the course of his career. Among them he received the Brandeis university Rosenteil Award in 1993, and the sloan-kettering Cancer Center Katherine Berkan Judd Award as well as the Genetics Society of America Medal in 1994. In 1995 he was awarded the MGH Warren Triennial Price and in 1996 was awarded the Columbia University Horwitz Award and the Passano Award. Dr. Hartwell received the Albert Lasker Award for medical research in 1998.

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Table of Contents

1 Genetics: The Study of Biological Information

2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity

3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype

4 The Chromosome Theory of Inheritance

5 Linkage, Recombination, and the Mapping of Genes on Chromosomes

6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information

7 Anatomy and Function of a Gene: Dissection Through Mutation

8 Gene Expression: The Flow of Genetic Information from DNA to RNA to Protein

9 Deconstructing the Genome: DNA at High Resolution

10 Reconstructing the Genome Through Genetic and Molecular Analysis

11 The Direct Detection of Genotype Distinguishes Individual Genomes

12 Systems Biology and Proteomics

13 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA

14 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes

15 The Prokaryotic Chromosome: Genetic Analysis in Bacteria

16 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of Inheritance

17 Gene Regulation in Prokaryotes

18 Gene Regulation in Eukaryotes

19 Cell-Cycle Regulation and the Genetics of Cancer

20 Using Genetics to Study Development

21 The Genetic Analysis of Populations and How They Evolve

22 Evolution at the Molecular Level
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