Genome Science: A Practical and Conceptual Introduction to Molecular Genetic Analysis in Eukaryotes

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More About This Textbook


Genome Science is a textbook and laboratory manual for advanced secondary and post-secondary education. It combines approachable narrative with extensively tested lab exercises that illustrate key concepts of genome biology in humans, invertebrates, and plants. Eighteen labs, organized into four chapters, engage students with both bioinformatics exercises and in vitro experiments. Each chapter also includes an extensive introduction that provides an historical and conceptual framework. This modular structure offers many options for enhancing existing courses, starting new courses, or supporting student research projects. The book is complete with advice for instructors, laboratory planning guidelines, recipes for solutions, and answers to student questions.
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Product Details

  • ISBN-13: 9780879698591
  • Publisher: Cold Spring Harbor Laboratory Press
  • Publication date: 6/28/2012
  • Pages: 690
  • Sales rank: 1,033,711
  • Product dimensions: 8.80 (w) x 11.20 (h) x 1.50 (d)

Table of Contents

1. Genome as Information Introduction Lab 1.1 Annotating Genomic DNA Lab 1.2 Detecting a Lost Chromosome Lab 1.3 Comparing Diversity in Eukaryotes Lab 1.4 Determining the Transposon Content in Grasses Lab 1.5 Identifying GAI Gene Family Members in Plants Lab 1.6 Discovering Evidence for Pseudogene Function Answers to Questions

2. The Human Genome Introduction Lab 2.1 Using Mitochondrial DNA Polymorphisms in Evolutionary Biology Lab 2.2 Using an Alu Insertion Polymorphism to Study Human Populations Lab 2.3 Using a Single-Nucleotide Polymorphism (SNP) to Predict Bitter-tasting Ability Laboratory Planning and Preparation Recipes for Reagents and Stock Solutions Answers to Questions

3. Genome Function Introduction Lab 3.1 Culturing and Observing C. elegans Lab 3.2 Using E. coli Feeding Strains to Induce RNAi and Knock Down Genes Lab 3.3 Examining the RNAi Mechanism Lab 3.4 Constructing an RNAi Feeding Vector Laboratory Planning and Preparation Recipes for Media, Reagents, and Stock Solutions Answers to Questions

4. Agricultural Genomics Introduction Lab 4.1 Detecting a Transposon in Corn Lab 4.2 Detecting a Transposon in Arabidopsis Lab 4.3 Linkage Mapping a Mutation Lab 4.4 Detecting Genetically Modified Foods by Polymerase Chain Reaction Lab 4.5 Using DNA Barcodes to Identify and Classify Living Things Laboratory Planning and Preparation Recipes for Reagents and Stock Solutions Answers to Questions

Cautions Appendix Subject Index

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