Geographical and Environmental Epidemiology: Methods for Small-Area Studies / Edition 1

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This book is the first to address both the theoretical and practical issues which arise when describing the geographical distribution of disease and investigating apparent disease clusters. Requirements in terms of population data, disease incidence and mortality are considered and related to the scale at which a study is being carried out. Statistical methods are reviewed for large scale correlation studies, intermediate scale smoothing exercises, and small scale clustering investigations, and the problems of interpretation are discussed. Problems of measuring environmental exposures at different scales are also reviewed. These issues are then related to current practice via a comprehensive set of case studies which include a large correlation study in China, clustering of asthma attacks, the Sellafield-leukemia cluster, environmental clusters of mesothelioma in Turkey, the investigation of disease following the industrial accident at Sevesco, and a multi-source study of cancer incidence around incinerators.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Product Details

  • ISBN-13: 9780192622358
  • Publisher: Oxford University Press
  • Publication date: 9/12/1996
  • Edition description: REPRINT
  • Edition number: 1
  • Pages: 404
  • Product dimensions: 6.13 (w) x 9.19 (h) x 0.84 (d)

Table of Contents

PART I; Introduction
1. Geographical Epidemiology and Ecological Studies, D. English
2. Small-Area Studies: Purpose and Methods, J. Cuzick and P. Elliott
3. Health and the Environment: The Significance of Chemicals and Radiation, G.K. Matthew
PART II: Data, Computational Methods, and Mapping
4. Mortality Data, A. Lopez
5. Cancer Incidence Data for Adults, A.J. Swerdlow
6. Cancer Incidence Data for Children, G.J. Draper and D.M. Parkin
7. Congenital Anomalies, H.M. Dolk and P. de Wals
8. Specialized Registers, A. Ahlbom and N. Hammar
9. Population Counts in Small Areas, I. Diamond
10. Use of Routine Data in Studies of Point Sources of Environmental Pollution, P. Elliott, I. Kleinschmidt, and J. Westlake
11. Socio-Economic Confounding, D. Jolley, B. Jarman, and P. Elliott
12. Use of Record Linkage in Small-Area Studies, E. Pukkala
13. Confidentiality, M.J. Quinn
14. Practical Approaches to Disease Mapping, M. Smans and J. Esteve
15. Estimating Environmental Exposures, G.A. Zapponi
16. Mapping Environmental Exposure, D.J. Briggs
PART III: Statistical Methods
17. Statistical Methods for Geographical Correlation Studies, S. Richardson
18. Bayesian Methods for Mapping Disease Risk
19. Statistical Methods for Analysing Point-Source Exposures, J.F. Bithell
20. Some Comments on Methods for Investigating Disease Risk Around a Point Source, M. Hills
21. Methods for the Assessment of Disease Clusters, F.E. Alexander and J. Cuzick
PART IV: Studies of Health and the Environment
22. Environmental Epidemiology: A Historical Perspective, B. Terracini
23. Guidelines for the Investigation of Clusters of Adverse Health Events, R.B. Rothenberg and S.B. Thacker
24. Studies of Disease Clustering: Problems of Interpretation, J. Urquhart
PART V: Case Studies
25. Childhood Leukemia Around the Sellafield Nuclear Plant, M.J. Gardner
26. The Epidemic of Respiratory Cancer Associated with Erionite Fibers in the Cappadocian Region of Turkey, Y.I. Baris, et al.
27. Soya Bean As A Risk Factor for Epidemic Asthma, J.M. Anto and J. Sunyer
28. The Seveso Accident, P.A. Bertazzi, A.C. Pesatori, and C. Zocchetti
29. Cancer of the Larynx and Lung Near Incinerators of Waste Solvents and Oils in Britain, P. Elliott et al.
30. A Study of Geographical Correlations in China, R. Peto, et al.

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