Giving Full Measure to Countermeasures:: Addressing Problems in the DoD Program to Develop Medical Countermeasures Against Biological Warfare Agents

Giving Full Measure to Countermeasures:: Addressing Problems in the DoD Program to Develop Medical Countermeasures Against Biological Warfare Agents

by Lois M. Joellenbeck, Jane S. Durch, Leslie Z. Benet, Development Committee on Accelerating the Research
     
 

ISBN-10: 0309091535

ISBN-13: 9780309091534

Pub. Date: 04/06/2004

Publisher: National Academies Press

In recent years, substantial efforts have been initiated to develop new drugs, vaccines, and other medical interventions against biological agents that could be used in bioterrorist attacks against civilian populations. According to a new congressionally mandated report from the Institute of Medicine and National Research Council of the National Academies, to

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Overview

In recent years, substantial efforts have been initiated to develop new drugs, vaccines, and other medical interventions against biological agents that could be used in bioterrorist attacks against civilian populations. According to a new congressionally mandated report from the Institute of Medicine and National Research Council of the National Academies, to successfully develop these drugs, vaccines, and other medical interventions against biowarfare agents, Congress should authorize the creation of a new agency within the Office of the Secretary of the U.S. Department of Defense. The committee recommended that Congress should improve liability protections for those who develop and manufacture these products, to stimulate willingness to invest in new research and development for biowarfare protection. Giving Full Measure to Countermeasures also identifies other challenges—such as the need for appropriate animal models and laboratories equipped with high-level biosafety protections—that will require attention if DoD efforts to develop new medical countermeasures are to be successful.

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Product Details

ISBN-13:
9780309091534
Publisher:
National Academies Press
Publication date:
04/06/2004
Pages:
160
Product dimensions:
6.00(w) x 9.00(h) x (d)

Table of Contents

Abbreviations and Acronymsxvii
Executive Summary1
1Ending Half-Measures for Countermeasures: The Challenge and Major Recommendations19
The Current Context for the Development of Medical Countermeasures20
Problems Hindering the DoD Effort25
Are Medical Countermeasures a Priority?31
Recommendations for Change35
References40
2Organizing Research and Development for Medical Countermeasures to Accomplish Essential Functions44
A DoD Agency for Acquisition of Medical Countermeasures for Biological Defense45
Consideration of Alternative Approaches64
References71
3Challenges in the Research and Development of Medical Countermeasures Against Biological Warfare Agents73
Engaging Academia and Industry74
Supporting the Regulatory Process82
Overcoming Current and Potential Resource Bottlenecks89
Ensuring the Availability of a Well-Trained Workforce94
References97
Appendixes
ABackground: The Current DoD Medical Biowarfare Countermeasures Program103
BAgendas for Information-Gathering Meetings117
CAcknowledgments127
DBiographical Sketches131

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