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The Gliomas
     

The Gliomas

by Mitchel S. Berger, Byron Wilson, Richard Zorab (Editor)
 

Researchers’ knowledge of gliomas continues to advance rapidly at both the basic and translational levels, and Gliomas provides a thorough overview of the evolving fields of tumor biology and clinical medicine as they relate to our understanding of brain tumors.

Gliomas reviews the current paradigms that underlie these fields, beginning

Overview

Researchers’ knowledge of gliomas continues to advance rapidly at both the basic and translational levels, and Gliomas provides a thorough overview of the evolving fields of tumor biology and clinical medicine as they relate to our understanding of brain tumors.

Gliomas reviews the current paradigms that underlie these fields, beginning with the molecular epidemiology of glioma susceptibility and prognosis through population-based science and genome-wide association studies. The book’s discussion of imaging modalities extends beyond advances in anatomical imaging to include metabolic and physiological studies. This work provides thorough discussion of the clinical view of tumors, ranging from the presentation of the patient to surgical management, and covers all therapeutic options for patient care, including chemotherapy, targeted molecular therapies, immunotherapies, and even personalized approaches to impact the set of lesions. Additionally, the book discusses radiotherapy with regard to the many options available to treat patients using myriad fractionated techniques with various sources. Finally, Gliomas reviews issues specific to the quality of life for patients, and techniques for maximizing the effect of caregivers.

Edited and authored by premier researchers from around the world, Gliomas is a comprehensive reference for clinicians and researchers seeking the most up-to-date information on gliomas, and a guide to the best ways to effectively manage glioma patients and their care.

  • Synthesizes widely dispersed information on the management of gliomas into one comprehensive resource
  • Chapters written by international authors who are preeminent researchers in the field
  • Fully explores the therapeutic options for patient care, from chemotherapy to radiotherapy to personalized approaches

Editorial Reviews

Doody's Review Service
Reviewer: Ben Zion Roitberg, MD (University of Illinois at Chicago College of Medicine)
Description: This text is a thorough review of the various aspects of neuro-oncology. It places emphasis on understanding the scientific basis of this discipline, and extensively reviews many experimental therapeutic approaches.
Purpose: The purpose is to track the advances in neuro-oncology and to provide individuals from all the related disciplines with the most thorough understanding of the field. The scope of the text is definitely wide enough, and the subjects are treated in adequate depth to meet the major goal of the editors. Unfortunately, the very multitude of attempted therapeutic modalities is a testimony to their limited success. Nevertheless, every practitioner in the field should be familiar with the experimental treatments, if only to answer patients' and families' questions.
Audience: This book was written for the clinician, the basic scientist, and the allied health provider in the field of neuro-oncology. Residents may find it too detailed and thus will prefer the general textbooks. It can serve as a common base of knowledge for all the providers in the field, and can be read all at once or used as a reference source. The editors are known leaders in neuro-oncology.
Features: This book follows the classic format of logically ordered chapters by eminent authorities in the field. The text covers all the aspects of neuro-oncology. The format is convenient, the print quality is very good, and most chapters are adequately illustrated. With so many contributors, and with subjects subdivided into short chapters, some duplication could not be avoided.
Assessment: This is a wide and thorough text. Much of the information here is already covered in the major textbooks in neurosurgery, but in significantly less detail. This book is most useful for its coverage of the entire field, bringing the specialties under one roof. I feel that it could be useful for any neurosurgeon, since most are frequently involved in the care of a glioma patient. Also, allied health professionals will find this a great store of knowledge and a handy reference. The neurosurgeon or the oncologist specializing in gliomas will probably not find much new information here, and will prefer a review of the current literature.
3 Stars from Doody
Ben Zion Roitberg
This text is a thorough review of the various aspects of neuro-oncology. It places emphasis on understanding the scientific basis of this discipline, and extensively reviews many experimental therapeutic approaches. The purpose is to track the advances in neuro-oncology and to provide individuals from all the related disciplines with the most thorough understanding of the field. The scope of the text is definitely wide enough, and the subjects are treated in adequate depth to meet the major goal of the editors. Unfortunately, the very multitude of attempted therapeutic modalities is a testimony to their limited success. Nevertheless, every practitioner in the field should be familiar with the experimental treatments, if only to answer patients' and families' questions. This book was written for the clinician, the basic scientist, and the allied health provider in the field of neuro-oncology. Residents may find it too detailed and thus will prefer the general textbooks. It can serve as a common base of knowledge for all the providers in the field, and can be read all at once or used as a reference source. The editors are known leaders in neuro-oncology. This book follows the classic format of logically ordered chapters by eminent authorities in the field. The text covers all the aspects of neuro-oncology. The format is convenient, the print quality is very good, and most chapters are adequately illustrated. With so many contributors, and with subjects subdivided into short chapters, some duplication could not be avoided. This is a wide and thorough text. Much of the information here is already covered in the major textbooks in neurosurgery, but in significantly less detail.This book is most useful for its coverage of the entire field, bringing the specialties under one roof. I feel that it could be useful for any neurosurgeon, since most are frequently involved in the care of a glioma patient. Also, allied health professionals will find this a great store of knowledge and a handy reference. The neurosurgeon or the oncologist specializing in gliomas will probably not find much new information here, and will prefer a review of the current literature.
Journal of the American Medical Association
The Gliomas is a first rate reference and will find its place on many a library shelf. There are other good monographs on the broad subject of brain tumors—Brain Tumors, by Kaye and Laws, comes to mind—but The Gliomas is a unique encyclopedia of this restricted topic. It will be indispensable to neurosurgeons, neuro-oncologists, and brain tumor researchers.

Product Details

ISBN-13:
9780721648255
Publisher:
Elsevier Health Sciences
Publication date:
01/28/1999
Edition description:
1st ed
Pages:
796
Product dimensions:
8.75(w) x 11.25(h) x (d)

Related Subjects

Meet the Author

Mitchel S. Berger M.D., F.A.C.S., F.A.A.N.S. is the Berthold and Belle N. Guggenhime Professor and Chairman of the Department of Neurological Surgery at the University of California, San Francisco (UCSF), and is an expert in the fields of neurosurgery and neuro-oncology. He also serves as Director of UCSF’s Brain Tumor Research Center.

After graduating from Harvard University in 1974, Dr. Berger earned his medical degree from the University of Miami School of Medicine. He completed a clinical fellowship in neuro-oncology at UCSF, a fellowship in pediatric neurosurgery at the Hospital for Sick Children of the University of Toronto, and his neurosurgical residency at UCSF. In 1986, he became Assistant Professor of Neurosurgery at the University of Washington School of Medicine, after which he was named Associate Professor (1990) and Professor (1996).

Dr. Berger has clinical expertise in treating adult and pediatric brain and spinal cord tumors. He is a pioneer of intraoperative brain mapping - a technique used to avoid functional areas of the brain during surgical resection of a tumor. His work has enabled surgeons to perform more extensive resection of tumor with less chance of producing sensorimotor or language deficit.

Dr. Berger is a leader of translational research and is the Principal Investigator of the UCSF Brain Tumor Research Center’s Specialized Program of Research Excellence in neuro-oncology, funded by the National Cancer Institute. His specific research interests lie in identifying molecular markers related to the progression and prognosis of glial tumors, as well as the development of small-molecule therapeutic agents that can be administered directly to the brain via convection-enhanced drug delivery.

During his distinguished career, Dr. Berger has served as President of the American Association of Neurological Surgeons, President of the Society of Neuro-Oncology, President of the North Pacific Society of Neurology, and Vice President of the Congress of Neurological Surgeons. He has also been a director of the American Board of Neurological Surgery and a member of the Board of Directors of the American Association of Neurological Surgeons. He is currently President of the American Academy of Neurological Surgery.

In 2009, Dr. Berger was awarded the prestigious Winn Prize by the Society for Neurological Surgery. He currently serves as a member of the National Football League Head, Neck and Spine Committee, focusing on retired players’ issues and examining the consequences of repetitive head injury and concussion. He is also an active member of numerous professional organizations, including the American Organization for Cancer Research, the American College of Surgeons, and the World Federation of Neurosurgical Societies.

A prolific author, Dr. Berger has contributed over 500 scientific articles to peer-reviewed journals, has edited 6 textbooks, and has written over 80 chapters on various neurosurgical topics. He is currently on the editorial boards of several leading journals including Neuro-Oncology and Neurosurgery.

Dr. Michael Weller has been Chairman of the Department of Neurology at the University Hospital Zurich, Switzerland, since 2008. He qualified in medicine in Cologne, Germany, after completing his thesis on proliferative disorders of the retina. A postdoctoral fellowship at the Department of Clinical Immunology, University Hospital Zurich, Switzerland, followed where he identified death receptor targeting as a potential treatment strategy for malignant gliomas. In 2005, he was appointed Chairman of the Department of General Neurology at the University Hospital Tübingen, Germany, where he had previously received his education in clinical neurology.

Dr. Weller has received several awards in recognition of his contributions to cancer research, including the German Cancer Award in 2007. He served as Chairman of the Neuro-Oncology Group of the German Cancer Society from 2001-2008. He is the Chairman of the German Glioma Network of the German Cancer Council, joined the Executive Board of the European Association for Neuro-Oncology (EANO) in 2010 and was elected President of EANO for 2014-2016. He is also the Chairman of the Brain Tumor Group of the European Organization for Research and Treatment of Cancer (EORTC).

Dr. Weller was involved in major practice-changing clinical trials including the registration trial for temozolomide in glioblastoma and served as PI on the NOA-03, NOA-04, NOA-08 and G-PCNSL-SG-1 trials in Germany and the DIRECTOR and ARTE trials in Switzerland . He is also a member of the editorial boards of the Journal of Neurochemistry, Journal of Neuro-Oncology, Brain and Glia, and he was the Associate Editor Europe of Neuro-Oncology from 2006-2013.

Dr. Weller has co-authored more than 550 original publications in peer-reviewed journals, including The New England Journal of Medicine, Science, Nature, Nature Medicine, Lancet Oncology, PNAS, The Journal of Clinical Investigation, and The Journal of Clinical Oncology.

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