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Goodman & Gilman's The Pharmacological Basis of Therapeutics [NOOK Book]

Overview

The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it.

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Goodman & Gilman's The Pharmacological Basis of Therapeutics

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Overview

The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it.

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Editorial Reviews

Doody's Review Service
Reviewer: Thomas L. Pazdernik, PhD (University of Kansas Medical Center)
Description: The 11th edition of Goodman & Gilman continues to be the most comprehensive and authoritative single source on the pharmacology of drugs. The first edition was published by Alfred Gilman and Louis Goodman in 1941. It soon became known as the bible of pharmacology and, even though editorship and chapter authorships have changed continuously from edition to edition, this remains the gold standard of pharmacology textbooks.
Purpose: The editors have done a remarkable job of condensing information from a rapidly expanding field to slightly reduce the number of pages from the previous edition while adhering to the principles of the original authors and retaining the completeness for which the book is known. The editors have standardized the organization to provide readers with essential physiology and basic pharmacology while providing the kinds of details a physician needs to know under easily identifiable headings. The editors have done a marvelous job in achieving the high standards expected by readers.
Audience: Although this publication may be too extensive for most students to read cover to cover while taking a pharmacology course, it should be a required resource for all who study, research, teach, or practice any facet of healthcare involving the use of medications.
Features: The 11th edition continues to provide the most comprehensive, current, and authoritative information on drugs. This latest version has new chapters on drug transporters, drug metabolism, and pharmacogenetics. The print version comes with a non-transferable subscription to an online digital version. Each drug in the digital version is hyperlinked to Gold Standards, Clinical Pharmacology Online, an online database. PDA downloads are available. In my view, this is by far the best electronic database available and includes information on FDA approval and black box warnings, mechanism of action, pharmacokinetics, chemical structure, pill photographs, indications, contraindications, adverse effects, dosages, patient education and much more. References in the digital version are also hyperlinked to PubMed.
Assessment: The print version should be on the reference shelf and the digital version on the computer desktop of all practicing pharmacologists, pharmacists, and physicians.
The Permanente Journal

There are few technical books that remain in a leadership position for 65 years. The Pharmacological Basis of Therapeutics is one. Physicians, teachers, and medical students have voted for Goodman & Gilman with their feet and with their pocketbooks for over six decades. The question is not whether this is an important and useful text, but why? ...While Goodman & Gilman is no quick-read, it is surprisingly clearly written, logical and interesting. It is also an awesome realization to see how much one never knew, added to what one knew but forgot.


4 Stars! from Doody
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Product Details

  • ISBN-13: 9780071608916
  • Publisher: McGraw-Hill Education
  • Publication date: 9/13/2005
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 11
  • Pages: 1984
  • File size: 58 MB
  • Note: This product may take a few minutes to download.

Meet the Author

Laurence L. Brunton, PhD

Professor of Pharmacology and Medicine

University of California, San Diego



Laurence Brunton trained under Alfred Goodman-Gilman and is nationally recognized for his expertise in cell signaling and cardivacular pharmacology. He has published more than 200 original research papers.


John S. Lazo, PhD

Professor and Chairman

Department of Pharmacology

University of Pittsburgh School of Medicine



Under John Lazo's leadership as Chairman, the Department of Pharmacology is regarded as one of the leading academic programs in the United States. He has published extensively in the field of cancer pharmacology.


Keith Parker, MD, PhD

Professor of Internal Medicine and Pharmacology

Division of Endocrinology

Department of Internal Medicine

University of Texas Southwestern School of Medicine

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Table of Contents

SECTION I: GENERAL PRINCIPLES

1. Pharmacokinetics and Pharmacodynamics

2. Drug Transport/Drug Transporters

3. Drug Metabolism

4. Pharmacogenomics

5. Principles of Therapeutics



SECTION II: DRUGS ACTING AT SYNAPTIC AND NEUROEFFECTOR JUNCTIONAL SITES

6. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems

7. Muscarinic Receptor Agonists and Antagonists

8. Anticholinesterase Agents

9. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia

10. Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists

11. 5-Hydroxytryptamine (Serotonin) Receptor Agonists and Antagonists



SECTION III: DRUGS ACTING ON THE CENTRAL NERVOUS SYSTEM

12. Neurotransmission and the Central Nervous System

13. History and Principles of Anesthesiology; General Anesthetics

14. Local Anesthetics

15. The Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium

16. Hypnotics and Sedatives

17. Introduction to Psychopharmacology: Drug Therapy of Depression and Anxiety Disorders

18. Pharmacotherapy of Psychosis and Mania

19. Drugs Effective in the Therapy of the Epilepsies

20. Treatment of Central Nervous System Degenerative Disorders

21. Opioid Analgesics

22. Ethanol

23. Drug Addiction and Drug Abuse



SECTION IV: AUTACOIDS: DRUG THERAPY OF INFLAMMATION

Introduction

24. Histamine, Bradykinin, and Their Antagonists

25. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor

26. Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout

27. Drugs Used in the Treatment of Asthma



SECTION V: DRUGS AFFECTING RENAL AND CARDIOVASCULAR FUNCTION

28. Diuretics

29. Vasopressin and Other Agents Affecting the Renal Conservation of Water

30. Renin and Angiotensin

31. Drugs Used for the Treatment of Myocardial Ischemia

32. Antihypertensive Agents and the Drug Therapy of Hypertension

33. Pharmacological Treatment of Heart Failure

34. Antiarrhythmic Drugs

35. Drug Therapy for Hypercholesterolemia and Dyslipidemia



SECTION VI: DRUGS AFFECTING GASTROINTESTINAL FUNCTION

36. Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers and Gastroesopheageal Reflux Disease

37. Prokinetic Agents, Antiemetics, and Agents Used in Irritable Bowel Syndrome

38. Agents Used of Diarrhea, Constipation, and Inflammatory Bowel Disease; Agents Used for Biliary and Pancreatic Disease



SECTION VII: CHEMOTHERAPY OF PARASITIC INFECTIONS

39. Drugs Used in the Chemotherapy of Protozoal Infections: Malaria

40. Drugs Used in the Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections

41. Drugs Used in the Chemotherapy of Helminthiasis



SECTION VIII: CHEMOTHERAPY OF MICROBIAL DISEASES

42. Antimicrobial Agents: General Considerations

43. Antimicrobial Agents (Continued): Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections

44. Antimicrobial Agents: Penicillins, Cephalosporins, and Other b-Lactam Antibiotics

45. Antimicrobial Agents: The Aminoglycosides

46. Antimicrobial Agents: Protein-Synthesis Inhibitors and Miscellaneous Antibacterial Agents

47. Antimicrobial Agents (Continued): Drugs Used in the Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy

48. Antimicrobial Agents: Antifungal Agents

49. Antimicrobial Agents: Antiviral Agents (Nonretroviral)

50. Antimicrobial Agents: Antiretroviral Agents



SECTION IX: CHEMOTHERAPY OF NEOPLASTIC DISEASES

Introduction

51. Antineoplastic Agents



SECTION X: DRUGS USED FOR IMMUNOMODULATION

52. Imunomodulators: Immunosuppressive Agents, Tolerogens, and Immunostimulants



SECTION XI: DRUGS ACTING ON THE BLOOD AND THE BLOOD-FORMING ORGANS

53. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins

54. Blood Coagulation and Anticoagulant, Thrombolytic, and Antiplatelet Drugs



SECTION XII: HORMONES AND HORMONE ANTAGONISTS

55. Pituitary Hormones and Their Hypothalamic Releasing Factors

56. Thyroid and Antithyroid Drugs

57. Estrogens and Progestins

58. Androgens

59. Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones

60. Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas

61. Agents Affecting Calcification and Bone Turnover: Calcium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds



SECTION XIII: DERMATOLOGY

62. Dermatological Pharmacology



SECTION XIV: OPHTHALMOLOGY

63. Ocular Pharmacology



SECTION XV: TOXICOLOGY

64. Principles of Toxicology; Treatment of Poisoning

65. Poisoning; Heavy Metals and Heavy-Metal Antagonists



APPENDICES

I. Principles of Prescription Order Writing and Patient Compliance

II. Design and Optimization of Dosage Regimens; Pharmacokinetic Data
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