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Doody's Review ServiceReviewer: Fulong Tan, PhD (University of Illinois at Chicago College of Medicine)
Description: This book, one in the Guidebook series, is a comprehensive guide to the structure and function of proteins involved in polypeptide folding.
Purpose: Recently gained knowledge in protein folding is so vast that even specialists find it difficult to keep up. The purpose of this book is to provide readers with a compendium of current knowledge about chaperones and folding catalysts. This is a worthy objective, as I have not seen a similar book, and the book achieves its goal.
Audience: The book is meant to provide an overview for researchers in the protein folding field (e.g., graduate students, postdoctoral fellows, principal investigators), and to help newcomers gain access to unfamiliar work rapidly. The book achieves its purpose and is appropriately targeted.
Features: The illustrations are adequate in number and of high quality. The bibliographies are concise and the references are relatively current. Other helpful features include: an overall list of abbreviations; a short abstract for each entry; an overview chapter for each protein family; GenBank accession numbers; and alternative names for the proteins. All of these features help readers to rapidly access needed information .
Assessment: This book describes important aspects of the structure, function, and regulation of all known chaperones and enzymes involved in protein folding. The information is up-to-date and the text is arranged in a concise and easy to read format. This is a useful handbook, not only for scientists in the protein folding field, but also for those working in related areas for whom the comprehensive summaries will be especially valuable. As a reference book in health science libraries, it will help newcomers become familiar with the field and rapidly find needed information.