Hairy-cell Leukaemiaby John Burthem, John C. Cawley
Hairy cell Leukaemia (HCL) has always attracted an interest out of all proportion to its frequency and continues to do so. There are two reasons for this. The first is that the disease is unusually responsive to therapy and second is that it has provided a number of important insights into B-cell biology. This monograph is a comprehensive account of hairy cell leukaemia and aims to provide a more detailed account than is available in the existing literature. The work is timely because a consensus has now emerged concerning accurate differential diagnosis a nd curative treatment. These aspects therefore form the focus of the book and are considered in detail. The basic advances in the laboratory that encourage the belief that elucidation of the underlying oncogenic event in the disease may be within reach. The background to this belief is extensively renewed. As a result the monograph will be of interest and practical value to both clinicians and researchers in this and related fields.
Description: This book represents a comprehensive review of an uncommon, but fascinating, disease.
Purpose: The purpose is to review the many advances in our understanding of the pathogenesis and treatment of hairy cell leukemia. Because there have been particularly gratifying advances in treatment with the purine analogs, these are worthy objectives that the authors meet well.
Audience: Although this book may have a relatively limited audience, it will be an important addition to the literature for students, residents and fellows in hematology-oncology, practicing hematologists-oncologists, and hematopathologists. The authors have studied and published extensively in hairy cell leukemia and write with authority.
Features: The illustrations add considerably to the text. The color photo micrographs are particularly pleasing. There are a number of electron microscopic photos that also add appeal to the text. The tables are clearly written and easy to understand.
Assessment: Given the remarkable advances that have occurred in the treatment of hairy cell leukemia, this comprehensive monograph is timely and thoroughly informative. One gets the sense that true progress has been made in understanding the biology and the critical features and treatment of at least one disease, albeit a rare one. Any medical library will welcome this text, as will hematopathologists and practicing hematologists-oncologists. In addition, the text will be of interest to anyone interested in understanding a success story in medical research.
- Springer London
- Publication date:
- Edition description:
- Softcover reprint of the original 1st ed. 1996
- Product dimensions:
- 6.10(w) x 9.25(h) x 0.01(d)
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