Handbook of Animal Models for the Rheumatic Diseases

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Detailed methods of the most widely used and best established animal models and related approaches to the study of rheumatic diseases and their treatment are presented in this major reference book. The detailed description of each model allows the reader to select the model most appropriate for his research and to reproduce the model without resorting to additional references. In addition, other methods for induction of the model, sources for procurement of suitable animals and validation of the model are highlighted. Methods for eliciting non-spontaneous phenomena, follow-up examinations and data collection are also described. Specific techniques such as joint-injection, obtaining synovial tissue, methods of assessment and similar non-specific information are emphasized. This easy-to-read resource text is essential for scientists, graduate students, research assistants, physicians and other invbestigators who use animal models for the study of rheumatic diseases.

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Product Details

  • ISBN-13: 9780849329883
  • Publisher: Taylor & Francis
  • Publication date: 9/30/1988
  • Pages: 256
  • Product dimensions: 0.85 (w) x 1.10 (h) x 0.60 (d)

Table of Contents

Volume I:
Adjuvant-Induced Polyarthritis in Rats
Type II Collagen-Induced Arthritis in Rats
Passivbe Collagen Arthritis Induced by Affinity Purified Anticollagen IgG
Streptococcal Cell Wall-Induced Arthritis in Rats
Lactobacillus casei Cell Wall-Induced Arthritis in Rats
Comparative Studies between Adjuvant, Type II Collagen, and Streptococcal Cell Wall-Induced Arthritis in Rats
Antigen-Induced Arthritis, Polyarthritis, and Tenosynovitis
Arthritis Induced by Total Lymphoid Irradiation
Inflammation Induced by 6-Sulfanilamidoindazol
Caprine Arthritis-Encephalitis Virus
Mycoplasma-Induced Arthritis in Rabbits
The Subcutaneous Air-Pouch Model of Inflammation
The Utility of the MRL/1 Mouse for Detecting Anti-Arthritic Drugs
Coxsackievirus B1-Induced Murine Polymyositis
Familial Canine Dermatomyositis
The Tight Skin(TSK)Mouse as an Experimental Model of Scleroderma
Avian Scleroderma
Experimental Pulmonary Fibrosis
Lactobacillus casei Cell Wall-Induced Coronary Arthritis in Mice: An Animal Model of Kawasaki's Disease

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