Handbook of Antihypertensive Therapy / Edition 8

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Overview

This new tenth edition has been completely updated and expanded to include the latest concepts, various changes in philosophy and approaches, clinical information, recent clinical trials, and new antihypertensive drugs and drug delivery systems.

The book contains black-and-white illustrations.

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Editorial Reviews

John F. Moran
This text is a pocket-sized summary of treatments, diagnoses, and evaluations of patients with hypertension. The main thrust of the book is not only to help control hypertension but, in addition, reduce end organ damage. The authors make a good point that hypertension is a big problem in the United States and is becoming bigger. Successful treatment of these patients is, indeed, a worthy objective. The text will be worthwhile for practitioners and medical residents who need a quick review of the management of hypertension. The text consists of tables, summaries, and lists of various aspects of hypertension. There are many lists, such as the Prevalence of Insulin Resistance, Nutritional Aspects of Non-Pharmacologic Treatment of Hypertension, Hemodynamics of Hypertension, and Effects of Antihypertensive Drugs. There are many graphs taken from papers in the literature to illustrate important points such as "The Probability of Stroke and Acute Myocardial Infarction." There is a short section on the selection of antihypertensive drugs based on subsets of hypertension. There is a two-page list of treatments for hypertensive emergencies. The use of monotherapy in combination therapy for hypertension is summarized, as are the maximum doses for various antihypertensive medications. There are short chapters on the highlights of all groups of antihypertensive drugs. These drugs are listed in tables and all notes refer to the Physicians' Desk Reference (Medical Economics) for further information. Illustrations are black-and-white; some are small due to the fact that this is truly a pocket-sized text. However, the text is well referenced with 134 well-annotated references.The reader can check the original articles if need be. This is the ninth edition of this handbook, which speaks to its popularity.
From The Critics
Reviewer: John F. Moran, MD (Loyola University Stritch School of Medicine)
Description: This is the 10th edition of a pocket-sized summary of the treatment, diagnosis, and evaluation of patients with hypertension.
Purpose: The purpose is to provide information to control hypertension and prevent organ damage. Moreover, the authors hope to promote vascular health. This is a worthy objective, since hypertension is a major health problem in the U.S.
Audience: The text would be worthwhile for practitioners and medical residents, as well as some students who need a quick review of the management of hypertension and some information on drug interactions.
Features: The book consists of tables and summaries, as well as lists of various aspects of hypertension. Many of the graphs are taken from original papers in the literature. The use of mono-therapy and combination therapy for hypertension is summarized, as are maximum doses for various antihypertensive medications. There are short chapters on the highlights of all groups of antihypertensive drugs. These medications are also listed in tables and all notes refer to the Physician's Desk Reference for further information. This edition adds information on neuropeptidase inhibitors, and adds coenzyme Q-10, as well as some information on the Mediterranean diet. There is more information in this edition on calcium channel blockers, as well angiotensin receptor blockers. The angiotensin converting enzyme inhibitors are also updated with the HOPE trial and the STOP trial. There also is more information on calcium channel blockers, and the trials: FACET, MIDAS, and HOT. As in the ninth edition, the illustrations are black and white. Some are small due to the fact that this is a pocket-sized text. The text is well referenced. There are 15 new references added to this edition, for a total of 149 pertinent references.
Assessment: This new edition of antihypertensive therapy is 10 pages longer than the previous one and adds some information on endocrine changes between an angiotensin aldosterone system and the sympathetic nervous system. There is also some reference to abnormal coagulation factors and endothelial dysfunction. It is a worthwhile text, but the main reason for publishing the 10th edition is probably that the 9th edition is out of print. It is obviously a popular text.
Doody's Review Service
Reviewer: John F. Moran, MD (Loyola University Stritch School of Medicine)
Description: This is the 10th edition of a pocket-sized summary of the treatment, diagnosis, and evaluation of patients with hypertension.
Purpose: The purpose is to provide information to control hypertension and prevent organ damage. Moreover, the authors hope to promote vascular health. This is a worthy objective, since hypertension is a major health problem in the U.S.
Audience: The text would be worthwhile for practitioners and medical residents, as well as some students who need a quick review of the management of hypertension and some information on drug interactions.
Features: The book consists of tables and summaries, as well as lists of various aspects of hypertension. Many of the graphs are taken from original papers in the literature. The use of mono-therapy and combination therapy for hypertension is summarized, as are maximum doses for various antihypertensive medications. There are short chapters on the highlights of all groups of antihypertensive drugs. These medications are also listed in tables and all notes refer to the Physician's Desk Reference for further information. This edition adds information on neuropeptidase inhibitors, and adds coenzyme Q-10, as well as some information on the Mediterranean diet. There is more information in this edition on calcium channel blockers, as well angiotensin receptor blockers. The angiotensin converting enzyme inhibitors are also updated with the HOPE trial and the STOP trial. There also is more information on calcium channel blockers, and the trials: FACET, MIDAS, and HOT. As in the ninth edition, the illustrations are black and white. Some are small due to the fact that this is a pocket-sized text. The text is well referenced. There are 15 new references added to this edition, for a total of 149 pertinent references.
Assessment: This new edition of antihypertensive therapy is 10 pages longer than the previous one and adds some information on endocrine changes between an angiotensin aldosterone system and the sympathetic nervous system. There is also some reference to abnormal coagulation factors and endothelial dysfunction. It is a worthwhile text, but the main reason for publishing the 10th edition is probably that the 9th edition is out of print. It is obviously a popular text.

3 Stars from Doody
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Product Details

  • ISBN-13: 9781560532712
  • Publisher: Elsevier Science
  • Publication date: 3/1/1998
  • Edition description: REVISED
  • Edition number: 8
  • Pages: 153

Table of Contents

Introduction
Abbreviations
Hypothesis: Essential Hypertension and End-Organ Damage 1
Hypertension in the United States and Classification 2
JNC VI 3
Secondary Hypertension 6
Indirect Measurement of Blood Pressure 8
Korotkoff Sounds 9
Common Mistakes in Blood Pressure Measurement 10
Hypertension-Atherosclerotic Syndrome 11
Nonpharmacologic Treatment of Hypertension 12
Obesity 14
Approaches to Selection of Antihypertensive Therapy 16
Hemodynamics in Hypertension 17
Hemodynamics: Logical and Preferred Method to Reduce Blood Pressure 18
Hemodynamic Effects of Antihypertensive Drugs 19
Hypertension-Related End-Organ Damage 21
Life Expectancy and Blood Pressure 22
Effects of Treatment of Hypertension 23
Selected Controlled, Randomized Clinical Trials with Diuretics and Beta-Blockers in Mild to Moderate Hypertension and Coronary Heart Disease, 1979-1992 24
Diuretic and Beta-Blocker Clinical Trials in Mild to Moderate Hypertension and Coronary Heart Disease: Summary 26
Clinical Hypertension Trials with Calcium Channel Blockers 27
Clinical Trials in Hypertension with Angiotension-Converting Enzyme Inhibitors: Conventional vs. New Therapy 32
Coronary Heart Disease: Risk Factors 36
Coronary Heart Disease: More Potential Risk Factors 37
Coronary Heart Disease Risk Factors: Influence of Diuretic and Beta-Blocker Therapy 39
Antihypertensive Drugs and Serum Lipids 40
Serum Lipids and Antihypertensive Therapy with Diuretics and Beta-Blockers: Summary 42
Effects of Antihypertensive Drugs on Coronary Heart Disease Risk Factors 44
Antihypertensive Drugs and Coronary Heart Disease Risk Factors: Summary 46
Calcium Channel Blockers and Atherosclerosis (Coronary Heart Disease Reduction) 48
Hypertension and Renal Damage 49
Hypertension-Related Renal Damage: Postulated Mechanisms 51
Hypertension, Renal Disease, and Antihypertensive Therapy 52
Effects of Antihypertensive Drugs on Renal Function 53
Hypertension and Diabetes Mellitus 54
Hypertensive Diabetics: Mortality and Coronary Heart Disease and Antihypertensive Therapy 58
Selection of Therapy Based on Subsets of Hypertension 59
Demographies and Antihypertensive Drugs 69
Resistant Hypertension 70
Hypertensive Urgencies and Emergencies 72
Hypertension in Pregnancy 78
Quality of Life and Antihypertensive Therapy (Selected Trials) 81
Total Cost of Antihypertensive Therapy 82
Characteristics of the Ideal Antihypertensive Drug 83
Combination Antihypertensive Therapy: Selected Drugs 84
Combination Antihypertensive Therapy: Selected Drugs: Summary 85
Antihypertensive Therapy: Efficacy of Monotherapy 85
Selected Drug Interactions with Antihypertensive Therapy 86
Maximum Recommended Doses of Antihypertensive Drugs with Best Treatment Characteristics 88
Diuretics 89
Diuretics Highlights 92
Central Alpha-Agonists 104
Central Alpha-Agonists: Similarities 105
Central Alpha-Agonists Highlights 106
Comparison of Commonly Used Oral Central Alpha-Agonists 112
Postganglionic Neural Inhibitors 113
Postganglionic Neural Inhibitors Highlights 114
Beta-Blockers - General 118
Side Effects and Contraindications of Beta-Blockers 121
Drugs Interactions with Beta-Blockers 123
Beta-Blockers Highlights 124
Direct Vasodilators 133
Direct Vasodilators Highlights 134
Alpha[subscript 1]-Blockers 135
Alpha[subscript 1]-Blockers Highlights 136
Angiotensin-Converting Enzyme (ACE) Inhibitors 138
ACE Inhibitors Highlights 142
Calcium Channel Blockers 146
Calcium Channel Blockers Highlights 148
Angiotensin II Receptor Blockers (ARBs) 156
Ang-II Receptor Blockers (ARBs) Highlights 160
Selected Combination Antihypertensive Drugs 163
Hypertension Drug Selection: Summary 164
New Antihypertensive Drug Classes 165
Conclusions 165
Subset Selection of Antihypertensive Therapy 166
References 167
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