Handbook Of Antioxidants, Second Edition / Edition 2

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Overview

Contains new and expanded material on antioxidants in beverages and herbal products, nitric oxide and selenium, and the effect of vitamin C on cardiovascular disease and of lipoic acid on aging, hyperglycemia, and insulin resistance!

Offering over 4200 contemporary references-2000 more than the previous edition-the Second Edition of the Handbook of Antioxidants is an up-to-the-minute source for nutritionists and dietitians, cell biologists and biochemists, cardiologists, oncologists, dermatologists, and medical students in these disciplines.

The book contains black-and-white illustrations.

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Editorial Reviews

Christine C. Tangney
This book is one in a series dedicated to the presentation of current research on free radical and antioxidant biology. It is intended to present an in-depth account of the chemical and biological aspects of select antioxidants, including vitamins E, C and A, the carotenoids, coenzyme Q, uric acid, melatonin (and aminoindoles), flavonoids (and polyphenols), tea antioxidants, those in gingko extracts, and alpha-lipoic acid. In the context of the many conflicting health claims and the plethora of epidemiological and clinical studies that have been recently published concerning a number of these ""nutrachemicals,"" this treatise is extremely timely. Authors were charged to provide a critical analysis of antioxidant ""therapy."" However, for several antioxidants, this component was either omitted or not warranted on the basis of current literature reviewed. In my opinion, the target audience should be nutrition scientists and other clinical scientists who can evaluate the studies in the context of strength of research designs, power, effect size, etc. However, many of the contributing authors are experts in their fields and present information in a highly integrated, critical fashion. Numerous helpful illustrations and tables are provided in most chapters. Most chapters are reasonably comprehensive and relatively up-to-date to 1994. Particular emphasis is given to vitamin E, with four chapters on the chemistry of vitamin E, tocopherol-mediated lipid peroxidation, biokinetics, and efficacy in health and disease. The chapter on Vitamin E biokinetics is highly readable and up-to-date. Other excellent chapters include ththose on the biology of vitamin C, the chemical aspects of coenzymeQ in scavenging radicals, the biological effects of carotenoids in humans, and the antioxidant actions of melatonin. Several other chapters were less comprehensive. Despite the less comprehensive chapters, this handbook provides an excellent resource to health professionals interested in understanding the current status of a number of nutrachemicals that may represent future preventive treatment choices.
From The Critics
Reviewer: Christine C. Tangney, PhD, MS (Rush Medical College of Rush University)
Description: This book is one in a series dedicated to the presentation of current research on free radical and antioxidant biology.
Purpose: It is intended to present an in-depth account of the chemical and biological aspects of select antioxidants, including vitamins E, C and A, the carotenoids, coenzyme Q, uric acid, melatonin (and aminoindoles), flavonoids (and polyphenols), tea antioxidants, those in gingko extracts, and alpha-lipoic acid. In the context of the many conflicting health claims and the plethora of epidemiological and clinical studies that have been recently published concerning a number of these "nutrachemicals," this treatise is extremely timely. Authors were charged to provide a critical analysis of antioxidant "therapy." However, for several antioxidants, this component was either omitted or not warranted on the basis of current literature reviewed.
Audience: In my opinion, the target audience should be nutrition scientists and other clinical scientists who can evaluate the studies in the context of strength of research designs, power, effect size, etc. However, many of the contributing authors are experts in their fields and present information in a highly integrated, critical fashion.
Features: Numerous helpful illustrations and tables are provided in most chapters. Most chapters are reasonably comprehensive and relatively up-to-date to 1994. Particular emphasis is given to vitamin E, with four chapters on the chemistry of vitamin E, tocopherol-mediated lipid peroxidation, biokinetics, and efficacy in health and disease. The chapter on Vitamin E biokinetics is highly readable and up-to-date. Other excellent chapters include ththose on the biology of vitamin C, the chemical aspects of coenzyme Q in scavenging radicals, the biological effects of carotenoids in humans, and the antioxidant actions of melatonin. Several other chapters were less comprehensive.
Assessment: Despite the less comprehensive chapters, this handbook provides an excellent resource to health professionals interested in understanding the current status of a number of nutrachemicals that may represent future preventive treatment choices.
Booknews
A comprehensive treatise on the chemical, biological, clinical, and some demographic aspects of antioxidant molecules, providing in-depth accounts of the current knowledge about particular antioxidant vitamins or naturally occurring compounds, and critical discussions of antioxidant therapy. Covers vitamins E and A, absorbic acid, coenzyme Q, uric acid, carotenoids, flavonoids and polyphenols, herbal antioxidants, melatonin and aminoindoles, and alpha-lipoic acid. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody
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Product Details

  • ISBN-13: 9780824705473
  • Publisher: CRC Press
  • Publication date: 11/29/2001
  • Series: Oxidative Stress and Disease Series
  • Edition description: Revised
  • Edition number: 2
  • Pages: 732
  • Product dimensions: 7.00 (w) x 10.00 (h) x 1.56 (d)

Table of Contents

General Topics

Food-Derived Antioxidants: How to Evaluate Their Importance in Food and In Vivo
Barry Halliwell
Measurement of Total Antioxidant Capacity in Nutritional and Clinical Studies
Guohua Cao and Ronald L. Prior
Quantification of Isoprostanes as Indicators of Oxidant Stress In Vivo
Jason D. Morrow, William E. Zackert, Daniel S. Van der Ende, Erin E. Reich, Erin S. Terry, Brian Cox, Stephanie C. Sanchez, Thomas J. Montine, and L. Jackson Roberts

Vitamin E

Efficacy of Vitamin E in Human Health and Disease
Sharon V. Landvick, Anthony T. Diplock, and Lester Packer
Vitamin E Bioavailability, Biokinetics, and Metabolism
Maret G. Traber
Biological Activity of Tocotrienols
Stefan U. Weber and Gerald Rimbach

Vitamin C

Vitamin C: From Molecular Mechanisms to Optimum Uptake
Sebastian J. Padayatty, Rushad Daruwala, Yaohui Wang, Peter Eck, Jian Song, Woo S. Koh, and Mark Levine
Vitamin C and Cardiovascular Diseases
Anitra C. Carr and Balz Frei
Epidemiological and Clinical Aspects of Ascorbate and Cancer
James E. Enstrom

Carotenoids

Carotenoids: Linking Chemistry, Absorption, and Metabolism to Potential Roles in Human Health and Disease
Denise M. Deming, Thomas W. M. Boileau, Kasey H. Heintz, Christine A. Atkinson, and John W. Erdman, Jr.
Antioxidant Effects of Carotenoids: Implication in Photoprotection in Humans
Wilhelm Stahl and Helmut Sies
Oxidative Breakdown of Carotenoids and Biological Effects of Their Metabolites
Werner G. Siems, Olaf Sommerburg, and Frederik J. G. M. van Kuijk
Carotenoids in the Nutrition of Infants
Olaf Sommerburg, Werner G. Siems, Kristina Meissner, and Michael Leichsenring
Human Studies on Bioavailability and Serum Response of Carotenoids
Elizabeth J. Johnson

Polyphenols and Flavonoids

Caffeic Acid and Related Antioxidant Compounds: Biochemical and Cellular Effects
João Laranjinha
Polyphenols and Flavonoids Protect LDL Against Atherogenic Modifications
Bianca Fuhrman and Michael Aviram
Phytoestrogen Content in Foods and Their Role in Cancer
Anna H. Wu and Malcolm C. Pike
Peroxynitrite Scavenging by Mitochondrial Reductants and Plant Polyphenols
Alberto Boveris, Silvia Alvarez, Silvia Lores Arnaiz, and Laura B. Valdez

Antioxidants in Beverages and Herbal Products

Antioxidant and Other Properties of Green and Black Tea
Philip J. Rijken, Douglas A. Balentine, C. A. J. van Mierlo, I. Paetau-Robinson, F. van de Put, Paul T. Quinlan, Ute M. Weisgerber, and Sheila A. Wiseman
The Phenolic Wine Antioxidants
Andrew L. Waterhouse
French Maritime Pine Bark: Pycnogenol
Gerald Rimbach, Fabio Virgili, and Lester Packer
Spices as Potent Antioxidants with Therapeutic Potential
Bharat B. Aggarwal, Nihal Ahmad, and Hasan Mukhtar

Lipoic Acid and Glutathione

Lipoic Acid: Cellular Metabolism, Antioxidant Activity, and Clinical Relevance
Oren Tirosh, Sashwati Roy, and Lester Packer
Cellular Effects of Lipoic Acid and Its Role in Aging
Régis Moreau , Wei-Jian Zhang, and Tory M. Hagen
Vascular Complications in Diabetes: Mechanisms and the Influence of Antioxidants
Peter Rösen, Hans-Jurgen Tritschler, and Lester Packer
Therapeutic Effects of Lipoic Acid on Hyperglycemia and Insulin Resistance
Erik J. Henriksen
Bioavailability of Glutathione
Dean P. Jones

Melatonin

Antioxidant Capacity of Melatonin
Russel J. Reiter, Dun-xian Tan, Lucien C. Manchester, and Juan R. Calvo
Radical and Reactive Intermediate-Scavenging Properties of Melatonin in Pure Chemical Systems
Maria A. Livrea, Luisa Tesoriere, Dun-xian Tan, and Russel J. Reiter

Selenium

Selenium: An Antioxidant?
Regina Brigelius-Flohé, Matilde Maiorino, Fulvio Ursini, and Leopold Flohé
Selenium Status and Prevention of Chronic Diseases
Paul Kneckt

Nitric Oxide

Antioxidant Properties of Nitric Oxide
Homero Rubbo and Rafael Radi

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