Handbook of Diagnosis and Treatment of Bipolar Disorders

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Overview

This readable guide to the assessment and management of patients with bipolar disorder can help physicians keep abreast of dramatic and rapid advances of recent years and integrate them into their practice. Handbook of Diagnosis and Treatment of Bipolar Disorders emphasizes recent controlled studies and FDA-approved indications and translates these data into the real world of clinical practice. The contributions of the eleven chapter authors from Stanford University reflect more than a decade of clinical research...

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Overview

This readable guide to the assessment and management of patients with bipolar disorder can help physicians keep abreast of dramatic and rapid advances of recent years and integrate them into their practice. Handbook of Diagnosis and Treatment of Bipolar Disorders emphasizes recent controlled studies and FDA-approved indications and translates these data into the real world of clinical practice. The contributions of the eleven chapter authors from Stanford University reflect more than a decade of clinical research and treatment undertaken at that institution, including advances in diagnosis and interventions supported by controlled studies. They provide crucial information regarding diagnosis, pharmacotherapy, psychotherapy, and treatment of patients from special populations -- such as children, women, and older adults -- and patients with particular challenging illness course such as rapid cycling.

This is the first book to provide quantitative assessment of potential benefit (number needed to treat) and risk (number needed to harm) for all approved treatments for bipolar disorder, providing clinicians with information needed to balance benefits and risks in order to render individualized state-of-the-art, evidence-based care. It describes all FDA-approved indications -- reviewing efficacy, safety, tolerability, pharmacokinetics, illness phase-specific dosing, and drug interactions. A chapter on multiphase treatment strategy explains crucial illness transition points and describes how these have been integrated with knowledge of illness phase in mood disorders. The book then demonstrates the relevance of this approach to therapeutics by providing: • An overview of pharmacotherapy that covers the emergence of evidence-based pharmacotherapy and number-needed-to-treat and -harm analyses.• Guidelines to managing acute manic and mixed episodes that include evidence-based assessments of lithium, divalproex, carbamazepine, and second-generation antipsychotics.• Coverage of acute major depressive episodes in bipolar disorders that outlines four tiers of treatment for this most pervasive illness phase with the fewest approved treatments.• Discussion of the longer-term management of bipolar disorders, including reviews of controlled trials of recently approved pharmacotherapies such as lamotrigine, olanzapine, aripiprazole, and adjunctive quetiapine. • A review of the use of mood stabilizers and second-generation antipsychotics, often in combinations, as well as the controversial role of adjunctive antidepressants in treating patients with rapid-cycling bipolar disorders. • Description of important advances in evidence-based adjunctive psychotherapeutic interventions in bipolar depression, and bipolar maintenance treatment.

Comprehensive in scope, yet readily accessible for application to clinical practice, the book includes summary tables, quick-reference lists of clinical pearls, and case studies to make its content more relevant. Handbook of Diagnosis and Treatment of Bipolar Disorders is the ideal source for integrating recent research into everyday practice.

American Psychiatric Publishing

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Editorial Reviews

Robert M. A. Hirschfeld

This "handbook" is a true tour de force for clinicians who want to acquire and/or improve their skills in the diagnosis and management of patients with bipolar disorder.

Doody's Review Service
Reviewer: Heather Huang, MD (University of Wisconsin School of Medicine and Public Health)
Description: This manual provides information on the diagnosis, pharmacotherapy, psychotherapy, and treatment of patients with bipolar disorders based on a review and summary of the most current clinical research.
Purpose: The purpose is to provide a handbook on the diagnosis and treatment of patients with bipolar disorders that translates data gathered from evidence-based medicine into clinical practice.
Audience: Clinicians involved in the care of individuals with bipolar disorders are the intended audience.
Features: The book is organized into sections based on diagnosis, treatment, and pharmacotherapy. The chapters on diagnosis take a critical look at the current DSM-IV-TR criteria for diagnosing the various bipolar disorders, examining both their strengths and limitations. Chapters on management address acute, continuation, and maintenance phases of treatment with a comprehensive review of current evidence-based literature. Specific sections are devoted to addressing special populations (e.g. children, women, older adults). Excellent graphs and tables concisely highlight key points of the literature.
Assessment: Treatment of bipolar disorders is both complex and rapidly changing. Management strategies often reflect a mix of clinical experience and evidence-based literature. This manual comprehensively distills the vast amount of literature examining the efficacy, safety, tolerability, pharmacokinetics, illness phase-specific dosing, and drug interactions of medications used to treat the various aspects of bipolar illness. It presents the information in a clinically relevant, wonderfully organized manner. I highly recommend this to any practitioner who provides care for individuals with bipolar illness.
From The Critics
Reviewer: Heather Huang, MD(Rush University Medical Center)
Description: This manual provides information on the diagnosis, pharmacotherapy, psychotherapy, and treatment of patients with bipolar disorders based on a review and summary of the most current clinical research.
Purpose: The purpose is to provide a handbook on the diagnosis and treatment of patients with bipolar disorders that translates data gathered from evidence-based medicine into clinical practice.
Audience: Clinicians involved in the care of individuals with bipolar disorders are the intended audience.
Features: The book is organized into sections based on diagnosis, treatment, and pharmacotherapy. The chapters on diagnosis take a critical look at the current DSM-IV-TR criteria for diagnosing the various bipolar disorders, examining both their strengths and limitations. Chapters on management address acute, continuation, and maintenance phases of treatment with a comprehensive review of current evidence-based literature. Specific sections are devoted to addressing special populations (e.g. children, women, older adults). Excellent graphs and tables concisely highlight key points of the literature.
Assessment: Treatment of bipolar disorders is both complex and rapidly changing. Management strategies often reflect a mix of clinical experience and evidence-based literature. This manual comprehensively distills the vast amount of literature examining the efficacy, safety, tolerability, pharmacokinetics, illness phase-specific dosing, and drug interactions of medications used to treat the various aspects of bipolar illness. It presents the information in a clinically relevant, wonderfully organized manner. I highly recommend this to any practitioner who provides care for individuals with bipolar illness.
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Product Details

  • ISBN-13: 9781585623136
  • Publisher: American Psychiatric Publishing, Incorporated
  • Publication date: 8/5/2009
  • Edition description: New Edition
  • Pages: 768
  • Sales rank: 818,771
  • Product dimensions: 6.00 (w) x 9.00 (h) x 1.70 (d)

Meet the Author

Terence A. Ketter, M.D., is Professor of Psychiatry and Behavioral Sciences in the Department of Psychiatry and Behavioral Sciences, and Chief of the Bipolar Disorders Clinic at Stanford University School of Medicine in Stanford, California.

American Psychiatric Publishing

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Table of Contents

Preface. Principles of assessment and treatment of patients with bipolar disorders. DSM-IV-TR diagnosis of bipolar disorders. Addressing clinical diagnostic challenges in bipolar disorders. Multiphase treatment strategy for bipolar disorders. Overview of pharmacotherapy for bipolar disorders. Management of acute manic and mixed episodes in bipolar disorders. Management of acute major depressive episodes in bipolar disorders. Longer-term management of bipolar disorders. Management of rapid-cycling bipolar disorders. Management of bipolar disorders in children and adolescents. Management of bipolar disorders in women. Management of bipolar disorders in older adults. Mood stabilizer and antipsychotics: pharmacokinetics, drug interactions, adverse effects, and administration. Antidepressant, anxiolytics/ hypnotics, and other medications: pharmacokinetucs, drug interactions, adverse effects, and administration. Adjunctive psychosocial interventions in the management of bipolar disorders. Appendices: Florida best practice medication guidelines for bipolar disorder. Quick reference medication facts. Quick reference resources and readings. Index.

American Psychiatric Publishing

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