The revised, updated Fourth Edition of this popular handbook provides practical, accessible information on all aspects of dialysis, with emphasis on day-to-day management of patients. Chapters provide complete coverage of hemodialysis, peritoneal dialysis, special problems in dialysis patients, and problems pertaining to various organ systems.
This edition reflects the latest guidelines of the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) on ...
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Handbook of Dialysis

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The revised, updated Fourth Edition of this popular handbook provides practical, accessible information on all aspects of dialysis, with emphasis on day-to-day management of patients. Chapters provide complete coverage of hemodialysis, peritoneal dialysis, special problems in dialysis patients, and problems pertaining to various organ systems.
This edition reflects the latest guidelines of the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) on hemodialysis and peritoneal dialysis adequacy and on nutrition. New chapters cover chronic kidney disease management in predialysis patients, frequent daily or nocturnal hemodialysis, and hemodiafiltration. Chapters on venous and arteriovenous access have been completely revised. Each chapter provides references to relevant Web sites.

This book contains black-and-white illustrations.

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Editorial Reviews

From The Critics
Reviewer: Kevin C Harned, MD(University of Kentucky College of Medicine)
Description: This is the fourth edition of an excellent resource on the range of renal replacement therapies. It covers all of the thus far approved modalities and includes well written sections on specific aspects of each one including adequacy, acid-base, electrolyte, how to manage complications, etc. This edition attempts to incorporate the updated National Kidney Foundation Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines/recommendations that were not available at the time of the previous edition five years ago.
Purpose: The authors attempt to fill certain voids in the third edition, specifically placing greater emphasis on chronic kidney disease (CKD) stages 3 and 4, providing more complete and current information on various aspects of water treatment and vascular access, and making it more user-friendly to practitioners worldwide by having direct unit conversions instead of leaving readers to convert the units themselves. Overall, the authors achieve these goals.
Audience: Practitioners from various backgrounds will find this useful. Experienced clinicians will appreciate the ability to quickly "grab-and-go" to review points they may not encounter daily. The less experienced clinicians and those in training will appreciate the ease of searching for specific information throughout the book as well as the relatively easy to read style. Nursing staff of dialysis units will certainly be able to appreciate the material, although most topics do not particularly target their clinical roles and consequently they would have to seek out further reading. This is a well written book from the most honored researchers in the field of nephrology.
Features: It begins with discussions regarding management of CKD, though it is not intended to be a complete resource. The review of hemodialysis, the importance of water purification, access, dosing, anticoagulation, complications, etc., progresses logically. Peritoneal dialysis, sometimes neglected in other books, is discussed well in a similar format, albeit in less detail than hemodialysis. The end of the book covers other aspects of renal replacement therapies, including anemia management (with the updated guidelines), diabetes-hypertension-cardiovascular disease risk modification, genitourinary changes that arise throughout the duration of CKD progression, etc. Most notably, despite the small size of this book (which is quite deceiving given the amount and quality of information provided), the authors take the time to methodologically explain a multitude of points via a discussion of real-life problems and go through them in a step-wise fashion enabling readers to see the reasoning behind the evaluation, diagnosis, and treatment. One criticism is that while some points are expressed in bold print, not all of the KDOQI updates are bolded, which was one of the objectives of this revision. A clear, emphasized statement in each section on the KDOQI recommendation on that topic, followed by the explanation, would have improved the presentation. This would enable clinicians to quickly locate the important points, while still allowing them to read later at their leisure.
Assessment: This is certainly superior to many of the larger nephrology texts such as Comprehensive Clinical Nephrology, 3rd edition, Feehally et al. (Elsevier, 2007), or Brenner & Rector's The Kidney, 7th edition, Brenner (Elsevier, 2004), when considering the ease and speed with which information can be retrieved. However, it should be viewed as a complement to these textbooks as the latter include much more in-depth discussion of the topics to foster a better understanding. Although this edition appears to be slightly superior to its predecessor in the information it imparts, those who already have the previous edition may not necessarily have to make the expenditure for this one. Those who have yet to obtain a copy and fellows in training certainly would benefit from having this newest version with the most up-to-date information.
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Product Details

  • ISBN-13: 9781451165913
  • Publisher: Wolters Kluwer Health
  • Publication date: 2/20/2012
  • Series: Lippincott Williams & Wilkins Handbook Series
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 4
  • Pages: 800
  • Sales rank: 844,358
  • File size: 15 MB
  • Note: This product may take a few minutes to download.

Table of Contents

Contributing Authors     xi
Preface     xix
Chronic Kidney Disease Management
Approach to Patients with Chronic Kidney Disease, Stages 1-4   Shona Pendse   Ajay Singh     3
Initiation of Dialysis   Shona Pendse   Ajay Singh   Edward Zawada, Jr.     14
Blood-Based Therapies
Physiologic Principles and Urea Kinetic Modeling   John T. Daugirdas     25
Hemodialysis Apparatus   Suhail Ahmad   Madhukar Misra   Nicholas Hoenich   John T. Daugirdas     59
Product Water and Hemodialysis Solution Preparation   Richard A. Ward   Todd S. Ing     79
Venous Catheter Access for Hemodialysis   Michael Allon   Jack Work     87
Arteriovenous Access for Hemodialysis   Victoria Kumar   Thomas Depner   Anatole Besarab   Shubha Ananthakrishnan     105
Acute Hemodialysis Prescription   John T. Daugirdas   Edward A. Ross   Allen R. Nissenson     127
Chronic Hemodialysis Prescription: A Urea Kinetic Approach   John T. Daugirdas     146
Complications During Hemodialysis   Richard A. Sherman   John T. Daugirdas   Todd S. Ing     170
Dialyzer Reuse   Allen M. Kaufman   Robert Levin   Ravi Jayakaran   Nathan W. Levin     192
Anticoagulation   Andrew Davenport   Kar Neng Lai   Joachim Hertel   Ralph J. Caruana     204
Slow Continuous Therapies   Boon Wee Teo   Jennifer S. Messer   Emil P. Paganini   John T. Daugirdas   Todd S. Ing     219
Frequent Hemodialysis   Gihad E. Nesrallah   Rita S. Suri   Robert M. Lindsay   Andreas Pierratos     252
Hemodiafiltration and Hemofiltration   Bernard Canaud   Detlef Krieter     265
Plasmapheresis   Nuhad Ismail   Dobri D. Kiprov   Raymond M. Hakim     275
Use of Dialysis and Hemoperfusion in Treatment of Poisoning   James F. Winchester   Adin Boldur   Chima Oleru   Chagriya Kitiyakara     299
Peritoneal Dialysis
Physiology of Peritoneal Dialysis   Peter G. Blake   John T. Daugirdas     323
Apparatus for Peritoneal Dialysis   Olof Heimburger   Peter G. Blake     339
Peritoneal Access Devices   Stephen R. Ash   John T. Daugirdas      356
Acute Peritoneal Dialysis Prescription   Stephen M. Korbet     377
Adequacy of Peritoneal Dialysis and Chronic Peritoneal Dialysis Prescription   Peter G. Blake     387
Volume Status and Fluid Overload in Peritoneal Dialysis   Neil Boudville   Peter G. Blake     410
Peritonitis and Exit Site Infection   David J. Leehey   Cheuk-Chun Szeto   Philip K-T Li     417
Mechanical Complications of Peritoneal Dialysis   Joanne M. Bargman     440
Metabolic Complications of Peritoneal Dialysis   Sarah S. Prichard     446
Clinical Problem Areas
Psychosocial Issues in End-stage Renal Disease Patients   Scott D. Cohen   Vicenzio Holder-Perkins   Paul L. Kimmel     455
Nutrition   Michael V. Rocco   T. Alp Ikizler     462
Serum Enzyme Levels   N. D. Vaziri   D. Kayichian     482
Diabetes   Antonios H. Tzamaloukas   David J. Leehey   Eli A. Friedman     490
Hypertension   Carmine Zoccali     508
Hematologic Abnormalities   Steven Fishbane     522
Infections   David J. Leehey   Joan P. Cannon   Joseph R. Lentino     542
Endocrine Disturbances   Michael J. Flanigan   Victoria S. Lim     575
Bone Disease   Daniel W. Coyne   Steven C. Cheng   James A. Delmez     583
Dialysis in Infants and Children   Susan R. Mendley     606
Cardiovascular Disease   Daniel E. Weiner   Anthony J. Nicholls   Mark J. Sarnak     626
The Digestive Tract   Susie Q. Lew   Juan P. Bosch     647
Genitourinary Tract and Male Reproductive Organs   Kar Neng Lai   Petras V. Kisielius   Biff F. Palmer     656
Obstetric and Gynecologic Issues   Susan Hou   Susan Grossman     672
Musculoskeletal and Rheumatic Diseases   Jonathan Kay     685
Nervous System and Sleep Disorders   Anthony J. Nicholls   Robert L. Benz   Mark R. Pressman     700
Aluminum, Lanthanum, and Strontium   Patrick C. D'Haese   Marc E. De Broe     714
Urea Kinetic Modeling: Tables and Figures     727
Molecular Weights and Conversion Tables     742
Subject Index     745
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