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Doody's Review ServiceReviewer: Melanie M. Brandabur, MD (University of Illinois at Chicago College of Medicine)
Description: This new book provides thorough coverage of the recent advances in dystonia genetics as well as excellent reviews of the primary and secondary causes of dystonia, the classification of generalized and focal dystonias, and a thorough discussion of the various treatment modalities.
Purpose: The authors have presented an extensive overview of the various aspects of dystonia, including emerging data on the genetic basis of many forms of this disorder. The chapters on treatment discuss in detail the medical treatment of dystonia as well as surgical techniques and chemical denervation with botulinum toxin. Botulinum toxin injection, as a relatively new and popular treatment, receives a particularly comprehensive exposition.
Audience: The editors and contributors are well known in the field and have targeted this volume toward those persons involved in dystonia treatment and research. It will also serve as an excellent reference for the general neurologist and other physicians and health professionals involved in the care of patients with dystonia.
Features: Among the many useful features of this book, the chapters on botulinum toxin injection provide a wealth of practical information for those interested in developing or expanding their expertise in these techniques. Specific details such as preparation of the toxin for injection, pharmacology of the toxin, and suggested injection sites contribute greatly to the usefulness of this book, as do chapters on injecting cranial and limb dystonias and spasmodic dysphonia.
Assessment: This is a well-researched book on a complex and incompletely understood topic. In view of the rapid expansion in the understanding of genetic aspects of dystonia, the current interest in botulinum toxin injection techniques, and the relative paucity of books on this subject, this is an important addition to the neurologic literature.