Handbook of Experimental Neurology: Methods and Techniques in Animal Research

Handbook of Experimental Neurology: Methods and Techniques in Animal Research

by Turgut Tatlisumak
     
 

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ISBN-10: 0521184207

ISBN-13: 9780521184205

Pub. Date: 12/23/2010

Publisher: Cambridge University Press

Basic relevant information on methodologies used in neurological disease models can be extremely hard to find. This major new reference work contains 30 chapters from over 60 internationally recognized scientists and covers every major methodology and disease model used in current neuroscience research. Divided into two major sections, the first deals with general

Overview

Basic relevant information on methodologies used in neurological disease models can be extremely hard to find. This major new reference work contains 30 chapters from over 60 internationally recognized scientists and covers every major methodology and disease model used in current neuroscience research. Divided into two major sections, the first deals with general methodologies in neuroscience research covering topics from animal welfare and ethical issues to surgical procedures, post-operative care and behavioral testing. Section two covers every major disease model including traumatic brain injury, ischemia and stroke, to Parkinson's, motor neurone disease, epilepsy and sleep disorders. Delivering critical, up-to-the-minute, methodological information and describing small animal models for almost all major neurological diseases, this book forms an essential reference for anyone working in neuroscience, from beginning students to experienced researchers and medical professionals.

  • Basic relevant infomation, including clearly labelled diagrams
  • All major disease models and methodologies in one volume
  • Written for beginners and young scientists

Product Details

ISBN-13:
9780521184205
Publisher:
Cambridge University Press
Publication date:
12/23/2010
Pages:
594
Product dimensions:
6.60(w) x 9.50(h) x 1.40(d)

Related Subjects

Table of Contents


List of contributors     viii
Principles and general methods     1
Introduction: Animal modeling - a precious tool for developing remedies to neurological diseases   Turgut Tatlisumak   Marc Fisher     3
Ethical issues, welfare laws, and regulations   David Whittaker     6
Housing, feeding, and maintenance of rodents   Robert W. Kemp     19
Identification of individual animals   Turgut Tatlisumak   Daniel Strbian     33
Analgesia, anesthesia, and postoperative care in laboratory animals   Naoya Masutomi   Makoto Shibutani     40
Euthanasia in small animals   Turgut Tatlisumak     67
Various surgical procedures in rodents   Rene Remie     75
Genetically engineered animals   Carolina M. Maier   Lilly Hsieh   Pak H. Chan     114
Imaging in experimental neurology   Marc Fisher   Eng H. Lo   Michael Lev     132
Safety in animal facilities   Tarja Kohila     147
Behavioral testing in small-animal models: ischemic stroke   Larry B. Goldstein     154
Methods for analyzing brain tissue   Paivi Liesi     173
Targeting molecularconstructs of cellular function and injury through in vitro and in vivo experimental models   Zhao Zhong Chong   Faqi Li   Kenneth Maiese     181
Neuroimmunology and immune-related neuropathologies   Bao-Guo Xiao   Hans Link     212
Animal models of sex differences in non-reproductive brain functions   George T. Taylor   Juergen Weiss   Frank Zimmermann     239
The ependymal route for central nervous system gene therapy   Erica Butti   Gianvito Martino   Roberto Furlan     257
Neural transplantation   Stephen B. Dunnett   Eduardo M. Torres   Monte A. Gates   Rosemary A. Fricker-Gates     269
Experimental models of major neurological diseases     309
Focal brain ischemia models in rodents   Fuhai Li   Turgut Tatlisumak     311
Rodent models of global cerebral ischemia   Julia Kofler   Richard J. Traystman     329
Rodent models of hemorrhagic stroke   Fatima A. Sehba   Joshua B. Bederson     345
In vivo models of traumatic brain injury   Ronen R. Leker   Shlomi Constantini     366
Experimental models for the study of CNS tumors   Taichang Jang   Lawrence Recht     375
Experimental models for demyelinating diseases   Jason M. Link   Richard E. Jones   Halina Offner   Arthur A. Vandenbark     393
Animal models of Parkinson's disease   Anumantha G. Kanthasamy   Siddharth Kaul     411
Animal models of epilepsy   Ricardo M. Arida   Alexandre V. Silva   Margareth R. Priel   Esper A. Cavalheiro     438
Experimental models of hydrocephalus   Osaama H. Khan   Marc R. del Bigio     457
Rodent models of experimental bacterial infections in the CNS   Tammy Kielian     472
Experimental models of motor neuron disease/amyotrophic lateral sclerosis   Ruth Danzeisen   Birgit Schwalenstocker   Albert C. Ludolph     487
Animal models for sleep disorders   Seiji Nishino   Nobuhiro Fujiki     504
Experimental models of muscle diseases   Anu Suomalainen   Katja E. Peltola Mjosund   Anders Paetau   Carina Wallgren-Pettersson     544
Index     562

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