Handbook of Pharmaceutical Excipients - Book + 1-Year Online Access Pkg

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The Handbook of Pharmaceutical Excipients is internationally recognised as the authoritative source of information on pharmaceutical excipients giving a comprehensive guide to uses, properties and safety. The new edition contains 340 fully revised monographs, with 40 new monographs including Cetyl Palmitate, Lysine Acetate, Pullulan, and Tromethamine. It includes newly added IR spectra for many excipients. The Handbook of Pharmaceutical Excipients now includes free one year's individual access to the online ...

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Overview

The Handbook of Pharmaceutical Excipients is internationally recognised as the authoritative source of information on pharmaceutical excipients giving a comprehensive guide to uses, properties and safety. The new edition contains 340 fully revised monographs, with 40 new monographs including Cetyl Palmitate, Lysine Acetate, Pullulan, and Tromethamine. It includes newly added IR spectra for many excipients. The Handbook of Pharmaceutical Excipients now includes free one year's individual access to the online version on MedicinesComplete. This offers all the attendant benefits, including searching the Handbook of Pharmaceutical Excipients online, and access to new and updated monographs. A secure code will be included in the package enabling the end-user to access MedicinesComplete and set up their account and their 1-year subscription. The Handbook collects together essential data on the physical properties of excipients as well as providing information on their safe use and potential toxicity. All 380 monographs are also thoroughly cross-referenced and indexed to allow their identification by chemical, non-proprietary or trade names. Unique benefits:
• Recognised internationally with expert contributors from across the world
• 380 fully-referenced monographs
• Extensively illustrated with SEMs and chemical structure diagrams, as well as two-colour IR and NIR spectra, line graphs and tables to support easy interpretation of the accompanying text.
• Directory of suppliers updated and indexed by country and by monograph, providing quick access to worldwide trade name and supplier information, including the specific grades or types of excipients that are commercially available.

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Editorial Reviews

Doody's Review Service
Reviewer: Patrick J McDonnell, Pharm.D.(Temple University School of Pharmacy)
Description: This is the seventh edition of a reference on the nonpharmacologically active components of drugs with monographs that demonstrate specific characteristics of each excipient. The previous edition was published in 2009.
Purpose: Although much attention is focused on the active component of drugs, it's important to remember that excipients used for delivery and administration are also components of these medications. These excipients, which have unique characteristics both for the formulation and stability of the product, also can affect patients. This is a thorough reference on these drug excipients.
Audience: The book certainly is useful for an array of professionals, including those in the drug industry, pharmaceutics, and drug design. As a pharmacist and a pharmacy educator who focuses on medication safety, I was intrigued by the safety information in the monographs. Students and others researching this topic will find this a very useful reference. A multiauthored book, it is written and reviewed by those working primarily in pharmaceutics and drug design.
Features: This edition covers 380 drug excipient monographs, which are arranged alphabetically. For each recipient, readers are able to reference nonproprietary names, chemical names and empiric chemical formulas, functional categories, applications in pharmaceutical formulations, chemical properties, stability and storage information, incompatibilities, safety and handling precautions, and other qualities and properties. Specific and general references for each product also are listed. Several appendixes provide a suppliers directory, detail excipient functional categories, and list related substances.
Assessment: This is certainly one of the most useful, complete, and concise references in this area. The authors and editors are committed to keep the information up to date, justifying this new edition.
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Product Details

  • ISBN-13: 9780857110275
  • Publisher: Pharmaceutical Press
  • Publication date: 6/1/2012
  • Edition number: 7
  • Pages: 1064
  • Product dimensions: 8.90 (w) x 11.10 (h) x 1.70 (d)

Table of Contents

International Steering Committee ix
Editorial Staff ix
Contributors x
About the Editors xii
New Monographs xiii
Related Substances xiv
Preface xvi
Arrangement xvii
Acknowledgments xix
Notice to Readers xix
Bibliography xx
Abbreviations xx
Units of Measurement xxii
Monographs
Acacia 1
Acesulfame Potassium 4
Acetic Acid, Glacial 6
Acetone 8
Acetyltributyl Citrate 10
Acetyltriethyl Citrate 12
Agar 14
Albumin 16
Alcohol 18
Alginic Acid 21
Aliphatic Polyesters 24
Alitame 28
Almond Oil 30
Alpha Tocopherol 32
Aluminum Hydroxide Adjuvant 36
Aluminum Oxide 38
Aluminum Phosphate Adjuvant 40
Aluminum Stearate 42
Ammonia Solution 44
Ammonium Alginate 46
Ascorbic Acid 48
Ascorbyl Palmitate 51
Aspartame 53
Attapulgite 56
Bentonite 58
Benzalkonium Chloride 61
Benzethonium Chloride 64
Benzoic Acid 66
Benzyl Alcohol 69
Benzyl Benzoate 72
Boric Acid 74
Bronopol 76
Butylated Hydroxyanisole 79
Butylated Hydroxytoluene 81
Butylparaben 83
Calcium Alginate 86
Calcium Carbonate 89
Calcium Phosphate, Dibasic Anhydrous 93
Calcium Phosphate, Dibasic Dihydrate 96
Calcium Phosphate, Tribasic 100
Calcium Stearate 102
Calcium Sulfate 105
Canola Oil 108
Carbomer 111
Carbon Dioxide 116
Carboxymethylcellulose Calcium 118
Carboxymethylcellulose Sodium 120
Carrageenan 124
Castor Oil 128
Castor Oil, Hydrogenated 130
Cellulose, Microcrystalline 132
Cellulose, Powdered 136
Cellulose, Silicified Microcrystalline 139
Cellulose Acetate 142
Cellulose Acetate Phthalate 145
Ceratonia 148
Cetostearyl Alcohol 150
Cetrimide 152
Cetyl Alcohol 155
Cetylpyridinium Chloride 157
Chitosan 159
Chlorhexidine 163
Chlorobutanol 168
Chlorocresol 171
Chlorodifluoroethane (HCFC) 174
Chlorofluorocarbons (CFC) 176
Chloroxylenol 180
Cholesterol 182
Citric Acid Monohydrate 185
Colloidal Silicon Dioxide 188
Coloring Agents 192
Copovidone 201
Corn Oil 204
Cottonseed Oil 206
Cresol 208
Croscarmellose Sodium 211
Crospovidone 214
Cyclodextrins 217
Cyclomethicone 222
Denatonium Benzoate 224
Dextrates 226
Dextrin 228
Dextrose 231
Dibutyl Phthalate 234
Dibutyl Sebacate 236
Diethanolamine 238
Diethyl Phthalate 240
Difluoroethane (HFC) 242
Dimethicone 244
Dimethyl Ether 246
Dimethyl Phthalate 248
Dimethyl Sulfoxide 250
Dimethylacetamide 253
Disodium Edetate 255
Docusate Sodium 257
Edetic Acid 260
Erythorbic Acid 264
Erythritol 266
Ethyl Acetate 268
Ethyl Lactate 270
Ethyl Maltol 272
Ethyl Oleate 274
Ethyl Vanillin 276
Ethylcellulose 278
Ethylene Glycol Palmitostearate 283
Ethylene Vinyl Acetate 285
Ethylparaben 287
Fructose 290
Fumaric Acid 293
Gelatin 295
Glucose, Liquid 299
Glycerin 301
Glyceryl Behenate 304
Glyceryl Monooleate 306
Glyceryl Monostearate 308
Glyceryl Palmitostearate 311
Glycofurol 313
Guar Gum 315
Hectorite 318
Heptafluoropropane (HFC) 321
Hexetidine 323
Hydrocarbons (HC) 325
Hydrochloric Acid 328
Hydroxyethyl Cellulose 330
Hydroxyethylmethyl Cellulose 334
Hydroxypropyl Cellulose 336
Hydroxypropyl Cellulose, Low-substituted 341
Hydroxypropyl Starch 344
Hypromellose 346
Hypromellose Acetate Succinate 350
Hypromellose Phthalate 354
Imidurea 359
Inulin 362
Iron Oxides 364
Isomalt 366
Isopropyl Alcohol 371
Isopropyl Myristate 374
Isopropyl Palmitate 376
Kaolin 378
Lactic Acid 381
Lactitol 383
Lactose, Anhydrous 385
Lactose, Monohydrate 389
Lactose, Spray-Dried 396
Lanolin 399
Lanolin Alcohols 402
Lanolin, Hydrous 404
Lauric Acid 406
Lecithin 409
Leucine 412
Linoleic Acid 414
Macrogol 15 Hydroxystearate 416
Magnesium Aluminum Silicate 418
Magnesium Carbonate 422
Magnesium Oxide 426
Magnesium Silicate 428
Magnesium Stearate 430
Magnesium Trisilicate 434
Malic Acid 436
Maltitol 438
Maltitol Solution 440
Maltodextrin 442
Maltol 445
Maltose 447
Mannitol 449
Medium-chain Triglycerides 454
Meglumine 457
Menthol 459
Methylcellulose 462
Methylparaben 466
Mineral Oil 471
Mineral Oil, Light 474
Mineral Oil and Lanolin Alcohols 476
Monoethanolamine 478
Monosodium Glutamate 480
Monothioglycerol 482
Myristic Acid 484
Neohesperidin Dihydrochalcone 486
Nitrogen 488
Nitrous Oxide 490
Octyldodecanol 492
Oleic Acid 494
Oleyl Alcohol 496
Olive Oil 498
Palmitic Acid 501
Paraffin 503
Peanut Oil 505
Pectin 507
Petrolatum 509
Petrolatum and Lanolin Alcohols 512
Phenol 514
Phenoxyethanol 517
Phenylethyl Alcohol 519
Phenylmercuric Acetate 521
Phenylmercuric Borate 524
Phenylmercuric Nitrate 526
Phosphoric Acid 530
Polacrilin Potassium 532
Poloxamer 535
Polycarbophil 539
Polydextrose 542
Polyethylene Glycol 545
Polyethylene Oxide 551
Polymethacrylates 553
Poly(methyl vinyl ether/maleic anhydride) 561
Polyoxyethylene Alkyl Ethers 564
Polyoxyethylene Castor Oil Derivatives 572
Polyoxyethylene Sorbitan Fatty Acid Esters 580
Polyoxyethylene Stearates 585
Polyvinyl Acetate Phthalate 589
Polyvinyl Alcohol 592
Potassium Alginate 594
Potassium Benzoate 596
Potassium Bicarbonate 598
Potassium Chloride 600
Potassium Citrate 603
Potassium Hydroxide 605
Potassium Metabisulfite 607
Potassium Sorbate 609
Povidone 611
Propionic Acid 617
Propyl Gallate 619
Propylene Carbonate 622
Propylene Glycol 624
Propylene Glycol Alginate 627
Propylparaben 629
2-Pyrrolidone 633
Raffinose 635
Saccharin 638
Saccharin Sodium 641
Saponite 644
Sesame Oil 646
Shellac 649
Simethicone 652
Sodium Acetate 654
Sodium Alginate 656
Sodium Ascorbate 659
Sodium Benzoate 662
Sodium Bicarbonate 665
Sodium Borate 669
Sodium Chloride 671
Sodium Citrate Dihydrate 675
Sodium Cyclamate 678
Sodium Hyaluronate 681
Sodium Hydroxide 683
Sodium Lactate 685
Sodium Lauryl Sulfate 687
Sodium Metabisulfite 690
Sodium Phosphate, Dibasic 693
Sodium Phosphate, Monobasic 696
Sodium Propionate 699
Sodium Starch Glycolate 701
Sodium Stearyl Fumarate 705
Sodium Sulfite 708
Sorbic Acid 710
Sorbitan Esters (Sorbitan Fatty Acid Esters) 713
Sorbitol 718
Soybean Oil 722
Starch 725
Starch, Pregelatinized 731
Starch, Sterilizable Maize 734
Stearic Acid 737
Stearyl Alcohol 740
Sucralose 742
Sucrose 744
Sugar, Compressible 748
Sugar, Confectioner's 750
Sugar Spheres 752
Sulfobutylether [beta]-Cyclodextrin 754
Sulfuric Acid 758
Sunflower Oil 760
Suppository Bases, Hard Fat 762
Talc 767
Tartaric Acid 770
Tetrafluoroethane (HFC) 772
Thaumatin 775
Thimerosal 777
Thymol 780
Titanium Dioxide 782
Tragacanth 785
Trehalose 788
Triacetin 790
Tributyl Citrate 792
Triethanolamine 794
Triethyl Citrate 796
Vanillin 798
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