Handbook of the Biology of Aging / Edition 6

Handbook of the Biology of Aging / Edition 6

by Edward J. Masoro
     
 

The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses.

The Sixth Edition is 20% larger than the Fifth Edition, with 21

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Overview

The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses.

The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship.

The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging.

The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.

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Product Details

ISBN-13:
9780120883875
Publisher:
Elsevier Science
Publication date:
12/01/2005
Series:
Handbooks of Aging Series
Edition description:
Older Edition
Pages:
682
Product dimensions:
1.50(w) x 10.00(h) x 7.00(d)

Table of Contents

1Reliability theory of aging and longevity3
2Are age-associated diseases an integral part of aging?43
3Dietary restriction, hormesis, and small molecule mimetics63
4Hematopoietic stem cells, aging, and cancer105
5Mitochondria : a critical role in aging124
6P53 and mouse aging models149
7Complex genetic architecture of Drosophila longevity181
8Evolutionary biology of aging : future directions217
9Senescence in wild populations of mammals and birds243
10Biodemography of aging and age-specific mortality in Drosophila melanogaster267
11Microarray analysis of gene expression changes in aging295
12Computer modeling in the study of aging334
13Dissecting the processes of aging using the nematode Caenorhabditis elegans360
14Genetic manipulation of life span in Drosophila Melanogaster400
15Juvenile and steroid hormones in Drosophila melanogaster longevity415
16A critical evaluation of nonmammalian models for aging research449
17Differential aging among skeletal muscles470
18Aging, body fat, and carbohydrate metabolism498
19Growth and aging : why do big dogs die young?512
20Growth hormone, insulin-like growth factor-1, and the biology of aging534
21Aging of the female reproductive system570

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