Harrison's Infectious Diseases, 2/E / Edition 2

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Overview

Infectious Diseases – as only Harrison’s can cover it

Featuring a superb compilation of chapters related to infectious diseases that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation.

Features

  • Current, complete coverage of need-to-know topics, including infections in organ systems, bacterial infections, viral infections, prion diseases, fungal infections, and protozoal infections
  • Addresses underlying epidemiologic, pathophysiologic, and genetic factors
  • Important material on HIV infections and AIDS by Anthony S. Fauci and H. Clifford Lane
  • Two image-based chapters comprise atlases valuable to clinical assessment: rashes associated with fever and blood smears of the various stages of the parasites causing malaria and babesiosis
  • Integration of pathophysiology with clinical management
  • 121 high-yield questions and answers drawn from Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 18e
  • Content updates and new developments since the publication of Harrison’s Principles of Internal Medicine, 18e
  • 132 chapters written by physicians who are recognized experts in the field of infectious diseases
  • Helpful appendix of laboratory values of clinical importance
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Editorial Reviews

Doody's Review Service
Reviewer: Robert Gene Penn, MD (Nebraska Methodist Hospital)
Description: This is an update of a 2010 book that compiles the 132 chapters related to infectious diseases that appear in Harrison's Principles of Internal Medicine, 18th edition, Longo et al. (McGraw-Hill, 2012). It provides concise and comprehensive coverage of infections in organ systems, bacterial infections, viral infections, prion diseases, fungal infections, and protozoal infections, while including new developments that have occurred since the publication of the previous edition.
Purpose: As with the first edition, this edition is intended as a convenient, standalone resource for accurate, accessible, up-to-date information on infectious diseases to meet point-of-care needs. In striving to meet immediate clinical needs, the information is presented in the context of underlying epidemiologic, pathophysiologic, and genetic factors. The authors take into consideration the formidable time and cost constraints facing clinicians. Moreover, topics are addressed from an international perspective.
Audience: It is ideal for clinicians in the clinic or ward, for the classroom, or for exam/certification preparation. The infectious disease coverage reflects the expertise of authors who are acknowledged authorities in their fields.
Features: The book provides specific recommendations regarding diagnostic options and therapeutic regimens, including antibiotics of choice, doses, durations, and alternatives. A new chapter, "The Human Microbiome" (chapter 3), summarizes the human microbiome projects and offers expert perspective on the critical relationship between the human body and its trillions of resident microbes. Also new is a highly practical chapter, "Health Care-Associated Infections" (chapter 14), that outlines infection concerns associated with healthcare and "bundled interventions." Self-assessment questions and answers are provided in an appendix at the end. The book is available both in a print version and as an eBook.
Assessment: This is an important, convenient resource that provides accurate, up-to-date integration of pathophysiology and clinical management of infectious diseases. With its full-color format, abundant illustrations yield key information in a user-friendly manner. Both students and clinicians will find this authoritative source of current information on infectious diseases extremely valuable.
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Product Details

  • ISBN-13: 9780071814829
  • Publisher: McGraw-Hill Professional Publishing
  • Publication date: 6/28/2013
  • Edition description: New Edition
  • Edition number: 2
  • Pages: 1456
  • Sales rank: 490,809
  • Product dimensions: 8.50 (w) x 10.70 (h) x 1.80 (d)

Meet the Author

Dennis L. Kasper, MD, MA (Hon)

William Ellery Channing Professor of Medicine

Professor of Microbiology and Molecular Genetics

Executive Dean for Academic Programs

Harvard Medical School

Director, Channing Laboratory

Department of Medicine

Brigham and Women’s Hospital

Anthony S. Fauci, MD

Chief, Laboratory of Immunoregulation

Director, National Institute of Allergy and Infectious Diseases

National Institutes of Health. In 2008, Dr. Fauci was awarded the Presidential Medal of Freedom, the Nation's highest civil award.

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Table of Contents

Contributors
Preface
SECTION I: INTRODUCTION TO INFECTIOUS DISEASES
1. Introduction to Infectious Diseases: Host-Pathogen Interactions, Lawrence C. Madoff, Dennis L. Kasper
2. Molecular Mechanisms of Microbial Pathogenesis, Gerald B. Pier
3. Immunization Principles and Vaccine Use, Gerald T. Keusch, Kenneth J. Bart, Mark Miller
4. Health Advice for International Travel, Gerald T. Keusch, Kenneth J. Bart, Mark Miller
5. Laboratory Diagnosis of Infectious Diseases, Alexander J. McAdam, Andrew B. Onderdonk
6. Microbial Bioterrorism, H. Clifford Lane, Anthony S. Fauci
SECTION II: FEVER AND APPROACH TO THE FEBRILE PATIENT
7. Fever and Hyperthermia, Charles A. Dinarello, Reuven Porat
8. Fever and Rash, Elaine T. Kaye, Kenneth M. Kaye
9. Fever of Unknown Origin, Jeffrey A. Gelfand, Michael V. Callahan
10. Atlas of Rashes Associated with Fever, Kenneth M. Kaye, Elaine T. Kaye
11. Infections in Patients with Cancer, Robert Finberg
12. Infections in Transplant Recipients, Robert Finberg, Joyce Fingeroth
13. Health Care-Associated Infections, Robert A. Weinstein
14. Approach to the Acutely Ill Infected Febrile Patient, Tamar F. Barlam, Dennis L. Kasper
15. Sever Sepsis and Septic Shock, Robert S. Munford
SECTION III: INFECTIONS IN ORGAN SYSTEMS
16. Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Tract Infections, Michael A. Rubin, Ralph Gonzales, Merle A. Sande
17. Pneumonia, Lionel A. Mandell, Richard Wunderink
18. Bronchiectasis and Lung Abcess, Gregory Tino, Steven E. Weinberger
19. Infective Endocarditis, Adolf W. Karchmer
20. Pericardial Disease, Eugene Braunwald
21. Infections of the Skin, Muscle, and Soft Tissues, Dennis L. Stevens
22. Osteomyelitis, Jeffrey Parsonnet
23. Infectious Arthritis, Lawrence C. Madoff
24. Intraabdominal Infections and Abscesses, Miriam J. Baron, Dennis L. Kasper
25. Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning, Joan R. Butterton, Stephen B. Calderwood
26. Acute Appendicitis and Peritonitis, Susan L. Gearhart, William Silen
27. Urinary Tract Infections, Pyelonephritis, and Prostatitis, Walter E. Stamm
28. Sexually Transmitted Infections: Overview and Clinical Approach, King K. Holmes
29. Meningitis, Encephalitis, Brain Abscess, and Empyema, Karen L. Roos, Kenneth L. Tyler
30. Chronic and Recurrent Meningitis, Walter J. Koroshetz, Morton N. Swartz
31. Chronic Fatigue Syndrome, Stephen E. Straus
32. Infectious Complications of Burns and Bites, Lawrence C. Madoff, Florencia Pereyra
SECTION IV: BACTERIAL INFECTIONS
Part 1: Approach to Therapy for Bacterial Diseases
33. Treatment and Prophylaxis of Bacterial Infections, Gordon L. Archer, Ronald E. Polk
Part 2: Diseases Caused by Gram-positive Bacteria
34. Pneumococcal Infections, Daniel M. Musher
35. Staphylococcal Infections, Franklin D. Lowy
36. Streptococcal and Enterococcal Infections, Michael R. Wessels
37. Acute Rheumatic Fever, Jonathan R. Carapetis
38. Diphtheria and Other Infections Caused by Corynebacteria and Related Species, William R. Bishai, John R. Murphy
39. Infections Caused by Listeria Monocytogenes, Elizabeth L. Hohmann, Daniel A. Portnoy
40. Tetanus, Elias Abrutyn
41. Botulism, Elias Abrutyn
42. Gas Gangrene and Other Clostridial Infections, Dennis L. Kasper, Lawrence C. Madoff
43. Clostridium difficile-Associated Disease, Including Pseudomembranous Colitis, Dale N. Gerding, Stuart Johnson
Part 3: Diseases Caused by Gram-Negative Bacteria
44. Meningococcal Infections, Lee M. Wetzler
45. Gonococcal Infections, Sanjay Ram, Peter A. Rice
46. Moraxella Infections, Daniel M. Musher
47. Haemophilus Infections, Timothy F. Murphy
48. Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria, Tamar F. Barlam, Dennis L. Kasper
49. Legionella Infection, Miguel Sabria, Victor L. Yu
50. Pertussis and Other Bordetella Infections, Scott A. Halperin
51. Diseases Caused by Gram-Negative Enteric Bacilli, Thomas A. Russo, James R. Johnston
52. Helicobacter pylori Infections, John C. Atherton, Martin J. Blaser
53. Infections Due to Pseudomonas Species and Related Organisms, Reuben Ramphal
54. Salmonellosis, David A. Pegues, Samuel I. Miller
55. Shigellosis, Philippe Sansonetti, Jean Bergounioux
56. Infections Due to Campylobacter and Related Species, Martin J. Blaser
57. Cholera and Other Vibrioses, Matthew K. Waldor, Gerald T. Keusch
58. Brucellosis, Michael J. Corbel, Nicholas J. Beeching
59. Tularemia, Richard F. Jacobs, Gordon E. Schutze
60. Plague and Other Yersinia Infections, David T. Dennis, Grant L. Campbell
61. Bartonella Infections, Including Cat-Scratch Disease, David H. Spach, Emily Darby
62. Donovanosis, Gavin Hart
Part 4: Miscellaneous Bacterial Infections
63. Nocardiosis, Gregory A. Filice
64. Actinomycosis, Thomas A. Russo
65. Infections Due to Mixed Anaerobic Organisms, Dennis L. Kasper, Ronit-Cohen-Poradosu
Part 5: Mycobacterial Diseases
66. Tuberculosis, Mario C. Raviglione, Richard J. O'Brien
67. Leprosy (Hansen's Disease), Robert H. Gelber
68. Nontuberculous Mycobacteria, C. Fordham von Reyn
69. Antimycobacterial Agents, Richard J. Wallace Jr., David E. Griffith
Part 6: Spirochetal Diseases
70. Syphilis, Sheila A. Lukehart
71. Endemic Treponematoses, Sheila A. Lukehart
72. Leptospirosis, Peter Speelman, Rudy Hartskeerl
73. Relapsing Fever, David T. Dennis
74. Lyme Borreliosis, Allen C. Steere
Part 7: Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae
75. Rickettsial Diseases, David H. Walker, J. Stephen Dumler, Thomas Marrie
76. Infections Due to Mycoplasmas, William M. McCormack
77. Chlamydial Infections, Walter E. Stamm
SECTION V: VIRAL INFECTIONS
Part 1: Viral Diseases: General Considerations
78. Medical Virology, Fred Wang, Elliott Kieff
79. Antiviral Chemotherapy, Excluding Antiretroviral Drugs, Lindsey R. Baden, Raphael Dolin
Part 2: Infections Due to DNA Viruses
80. Herpes Simplex Viruses, Laurence Corey
81. Varicella-Zoster Virus Infections, Richard J. Whitley
82. Epstein-Barr Virus Infections, Including Infectious Mononucleosis, Jeffrey I. Cohen
83. Cytomegalovirus and Human Herpesvirus Types 6,7, and 8, Martin S. Hirsch
84. Molluscum Contagiosum, Monkeypox, and Other Poxviruses, Excluding Smallpox Virus, Fred Wang
85. Parvovirus Infections, Kevin E. Brown
86. Human Papillomavirus Infections, Richard C. Reichman
Part 3: Infections Due to DNA and RNA Respiratory Viruses
87. Common Viral Respiratory Infections and Severe Acute Respiratory Syndrome (SARS), Raphael Dolin
88. Influenza, Raphael Dolin
Part 4: Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses
89. The Human Retroviruses, Dan L. Longo, Anthony S. Fauci
90. Human Immunodeficiency Virus Disease: AIDS and Related Disorders, Anthony S. Fauci, H. Clifford Lane
Part 5: Infections Due to RNA Viruses
91. Viral Gastroenteritis, Umesh D. Parashar, Roger I. Glass
92. Acute Viral Hepatitis, Jules L. Dienstag
93. Chronic Hepatitis, Jules L. Deinstag
94. Enteroviruses and Reoviruses, Jeffrey I. Cohen
95. Measles (Rubeola), Anne Gershon
96. Rubella (German Measles), Anne Gershon
97. Mumps, Anne Gershon
98. Rabies and Other Rhabdovirus Infections, Alan C. Jackson, Eric C. Johannsen
99. Infections Caused by Arthropod- and Rodent-Borne Viruses, Clarence J. Peters
100. Ebola and Marburg Viruses, Clarence J. Peters
SECTION VI: PRION DISEASES
101. Prion Diseases, Stanley B. Prusiner, Bruce L. Miller
SECTION VII: FUNGAL AND ALGAL INFECTIONS
102. Diagnosis and Treatment of Fungal Infections, John E. Edwards, Jr.
103. Histoplasmosis, Chadi A. Hage, L. Joseph Wheat
104. Coccidioidomycosis, Neil M. Ampel
105. Blastomycosis, Stanley W. Chapman, Donna C. Sullivan
106. Cryptococcosis, Arturo Casadevall
107. Candidiasis, John E. Edwards, Jr.
108. Aspergillosis, David W. Denning
109. Mucormycosis, Alan M. Sugar
110. Miscellaneous Mycoses and Algal Infections, Stanley W. Chapman, Donna C. Sullivan
111. Pneumocystis Infection, A. George Smulian, Peter D. Walzer
SECTION VIII: PROTOZOAL AND HELMINTHIC INFECTIONS
Part 1: Parasitic Infections: General Considerations
112. Laboratory Diagnosis of Parasitic Infections, Sharon L. Reed, Charles E. Davis
113. Agents Used to Treat Parasitic Infections, Thomas A. Moore
114. Pharmacology of Agents Used to Treat Parasitic Infections, Thomas A. Moore
Part 2: Protozoal Infections
115. Amebiasis and Infection With Free-Living Amebas, Sharon L. Reed
116. Malaria, Nicholas J. White, Joel G. Breman
117. Babesiosis, Jeffrey A. Gelfand, Edouard Vannier
118. Atlas of Blood Smears of Malaria and Babesiosis, Nicholas J. White, Joel G. Breman
119. Leishmaniasis, Barbara L. Herwaldt
120. Trypanosomiasis, Louis V. Kirchhoff
121. Toxoplasma Infections, Lloyd H. Kasper
122. Protozoal Intestinal Infections and Trichomoniasis, Peter F. Weller
Part 3: Helminthis Infections
123. Trichinella and Other Tissue Nematodes, Peter F. Weller
124. Intestinal Nematodes, Peter F. Weller, Thomas B. Nutman
125. Filarial and Related Infections, Thomas B. Nutman, Peter F. Weller
126. Schistosomiasis and Other Trematode Infections, Adel A.F. Mahmoud
127. Cestodes, A. Clinton White, Jr., Peter F. Weller
Appendix:
Laboratory Values of Clinical Importance, Alexander Kratz, Michael A. Pesce, Daniel J. Fink
Review and Self-Assessment:
Charles Wiener, Gerald Bloomfield, Cynthia D. Brown, Joshua Schiffer, Adam Spivak
Index

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