Harrison's Nephrology and Acid-Base Disorders, 2e / Edition 2

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Nephrology and Acid-Base Disorders – as only Harrison’s can cover it

Featuring a superb compilation of chapters related to kidney function that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation.


  • Sections that reflect the scope of nephrology: Introduction to the Renal System; Alterations of Renal Function and Electrolytes; Acute Kidney Injury and Chronic Renal Failure; Glomerular and Tubular Disorders; Renal Vascular Disease; Urinary Tract Infections and Obstruction; and Cancer of the Kidney and Urinary Tract
  • Complete coverage of a broad spectrum of topics, including acid-base and electrolyte disorders, vascular injury to the kidney, and specific diseases of the kidney
  • Integration of pathophysiology with clinical management
  • 41 high-yield questions and answers drawn from Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 18e
  • Content updates and new developments since the publication of Harrison’s Principles of Internal Medicine, 18e
  • 22 chapters written by physicians who are recognized experts in the field of nephrology and acid-base disorders
  • Helpful appendix of laboratory values of clinical importance
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Editorial Reviews

Doody's Review Service
Reviewer: Jon Webb, MD (University of Kentucky College of Medicine)
Description: This is the second edition of a review of renal topics, including acid-base and electrolyte disorders, vascular injury to the kidney, and specific diseases of the kidney.
Purpose: The goal is to provide a reference for managing patients with kidney disease. Each chapter is written by a leading expert who has been challenged to summarize the latest available information about the clinical management of kidney diseases.
Audience: This is an excellent tool for nephrologists, both clinical and research oriented. The colorful display and design will also attract medical students, internists, and pediatricians.
Features: The 22 chapters are grouped into seven sections that reflect the scope of nephrology. The first section provides a systems overview, beginning with renal development, function, and physiology, as well as how the kidney responds to injury. Each of the subsequent disease-oriented chapters integrates pathophysiology with clinical management. Each chapter has colorful tables and figures to enhance learning, and the clinical pearls, which are highlighted, are well written and concise. Some suggested enhancements include a list of key learning points or objectives in each chapter, specific questions, or, in this age of web-based resources, a link to an online version.
Assessment: This is a useful tool for reviewing the broad field of nephrology. It is well written, easy to read, and highlights the key points with attractive designs. Overall, it is a strong resource for medical students and residents on nephrology rotations or preparing for boards. The book is also helpful as a teaching resource for professionals in education.
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Product Details

  • ISBN-13: 9780071814966
  • Publisher: McGraw-Hill Professional Publishing
  • Publication date: 5/10/2013
  • Edition number: 2
  • Pages: 336
  • Sales rank: 1,449,332
  • Product dimensions: 8.50 (w) x 10.80 (h) x 0.70 (d)

Meet the Author

McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

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Table of Contents



Section I Introduction to the Renal System

1 Basic Biology of the Kidney Eric G. Neilson Neilson, Eric G. 2

2 Adaptation of the Kidney to Renal Injury Eric G. Neilson Neilson, Eric G. 14

Section II Alterations of Renal Function and Electrolytes

3 Azotemia and Urinary Abnormalities Barry M. Brenner Brenner, Barry M. 22

4 Atlas of Urinary Sediments and Renal Biopsies Eric G. Neilson Neilson, Eric G. 32

5 Acidosis and Alkalosis Thomas D. DuBose, Jr. DuBose, Thomas D., Jr. 42

6 Fluid and Electrolyte Disturbances Barry M. Brenner Brenner, Barry M. 56

7 Hypercalcemia and Hypocalcemia Sundeep Khosla Khosla, Sundeep 73

8 Hyperuricemia and Gout Lan X. Chen Lan, X. Chen 78

9 Nephrolithiasis Murray J. Favus Favus, Murray J. 88

Section III Acute and Chronic Renal Failure

10 Acute Renal Failure Glenn M. Chertow Chertow, Glenn M. 98

11 Chronic Kidney Disease Karl Skorecki Skorecki, Karl 113

12 Dialysis in the Treatment of Renal Failure Glenn M. Chertow Chertow, Glenn M. 130

13 Transplantation in the Treatment of Renal Failure Mohamed H. Sayegh Sayegh, Mohamed H. 137

14 Infections in Transplant Recipients Joyce Fingeroth Fingeroth, Joyce 147

Section IV Glomerular and Tubular Disorders

15 Glomerular Diseases Eric G. Neilson Neilson, Eric G. 156

16 Polycystic Kidney Disease and Other Inherited Tubular Disorders Parul S. Patel Patel, Parul S. 180

17 Tubulointerstitial Diseases of the Kidney Barry M. Brenner Brenner, Barry M. 196

Section V Renal Vascular Disease

18 Vascular Injury to the Kidney Barry M. Brenner Brenner, Barry M. 204

19 Hypertensive Vascular Disease Theodore A. Kotchen Kotchen, Theodore A. 212

Section VI Urinary Tract Infections and Obstruction

20 Urinary Tract Infections, Pyelonephritis, and Prostatitis Walter E. Stamm Stamm, Walter E. 236

21 Urinary Tract Obstruction Barry M. Brenner Brenner, Barry M. 248

Sction VII Cancer of the Kidney and Urinary Tract

22 Bladder and Renal Cell Carcinomas Robert J. Motzer Motzer, Robert J. 254

Appendix Laboratory Values of Clinical Importance Daniel J. Fink Fink, Daniel J. 261

Review and Self-Assessment Adam Spivak Spivak, Adam 277

Index 299

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