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Harrison's Principles of Internal Medicine, 18th Edition (Volumes 1 and 2) [NOOK Book]


The most trusted textbook in medicine -- featuring the acclaimed Harrison's DVD with 57 additional chapters and exclusive video and tutorials

Now presented in TWO VOLUMES

As reviwed by JAMA:

"With the 18th edition, Harrison's Principles of Internal Medicine retains ...
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Harrison's Principles of Internal Medicine, 18th Edition (Volumes 1 and 2)

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The most trusted textbook in medicine -- featuring the acclaimed Harrison's DVD with 57 additional chapters and exclusive video and tutorials

Now presented in TWO VOLUMES

As reviwed by JAMA:

"With the 18th edition, Harrison's Principles of Internal Medicine retains its standing as a definitive clinical reference and remains an outstanding foundation for any physician or physician-in-training. In many regards, Harrison’s remains synonymous not just with internal medicine but with medicine in general. The editors of the 18th edition have skillfully balanced tradition with the desire and need for innovation. The result is a book that remains as fundamental to current medical practice as the first edition was in 1949."


Extensively revised and expanded by the world’s leading physicians, Harrison’s Principles of Internal Medicine, 18e continues to set the standard as the pinnacle of current medical knowledge and practice, offering the definitive review of disease mechanisms and management.


All chapters have been completely updated to reflect the latest knowledge and evidence, and important new chapters have been added, including: "Systems Biology in Health and Disease," "The Human Microbiome," "The Biology of Aging," and "Neuropsychiatric Illnesses in War Veterans."


Harrison's covers more global aspects of medicine than any other textbook, and features such chapters as "Global Issues in Medicine," by Jim Yong Kim, Paul Farmer, and Joseph Rhatigan, and new to the 18th edition, "Primary Care in Low and Middle Income Countries."


No other resource delivers coverage of disease mechanisms and management like Harrison's, including world-renowned chapters on HIV/AIDS, STEMI and non-STEMI myocardial infarction, cancer biology, multiple sclerosis, and diabetes.

The Harrison’s Multi-Media DVD— Better Than Ever!

The Harrison’s DVD has been expanded to include an extensive video demonstration of the neurological physical examination, and video tutorials on how to perform essential clinical procedures, including:

  • Thoracentesis

  • Abdominal Paracentesis

  • Endotracheal Intubation

  • Central Venous Catheter Placement

57 additional chapters and more than 2,000 images make the companion DVD an essential part of every physician's education, practice, and lifelong learning.The DVD also features PowerPoint presentations from fifty chapters to facilitate classroom lectures, and a free trial subscription to (including Harrison's Online).

Harrison’s 18e is proud to present a tribute to longtime editor, Eugene Braunwald, MD for his outstanding and continuing contributions to medical knowledge and practice.

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Editorial Reviews

Doody's Review Service
Reviewer: Heather Huang, MD (University of Wisconsin School of Medicine and Public Health)
Description: The eighteenth edition of Harrison's Principles of Internal Medicine comes with new chapters, including "Systems Biology in Health and Disease," "The Human Microbiome," "The Biology of Aging," and "Neuropsychiatric Illnesses in War Veterans," and an updated DVD.
Purpose: It is intended to provide the foundation that is essential to understanding the various aspects of internal medicine. It continues to focus on the pathophysiological basis of disease while discussing clinical relevance, approach, and management. It additionally seeks to update and extensively modify the previous edition to discuss the areas of medicine that have evolved since that book was published 2008.
Audience: Written for a wide variety of audiences, the book primarily targets anyone involved in the field of medicine, whether in clinical or research realms, and students.
Features: Covering nearly every possible topic in the field of medicine, the book begins with a phenomenal overview of clinical medicine, discussing important topics such as global medicine, decision-making in clinical practice, the concepts of disease screening and prevention, as well as the importance of medical disorders in specific groups (e.g. women, surgical patients, end of life). The extensive chapters that follow focus on a symptom-based presentation of disease and then illness organized by organ system. Numerous tables, graphs, and figures add further clarity to the text. The accompanying DVD includes extensive video and image collections of pathology, histology, procedures, additional lectures, and radiology. The chapters on psychiatric disease could be expanded to focus more on the relevance that psychiatric illness has to medical disease.
Assessment: Written by experts in the field, this book is updated with the latest advances in pathophysiology and treatment. It is organized in a way that makes reading from beginning to end a logical journey, yet each chapter can stand alone as a quick reference on a particular topic. The DVD will serve as an invaluable resource for any clinician, student, or researcher. Future editions could work toward strengthening the sections on psychiatric disorders and mental health given their prevalence and significant impact on individuals with comorbid disease.
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Product Details

  • ISBN-13: 9780071748902
  • Publisher: McGraw-Hill Education
  • Publication date: 8/11/2011
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 18
  • Pages: 4012
  • Sales rank: 832,169
  • File size: 239 MB
  • Note: This product may take a few minutes to download.

Meet the Author

About the Editors

Dan L. Longo, MD,

Lecturer, Department of Medicine, Harvard Medical School

Senior Physician, Brigham and Women's Hospital

Deputy Editor, New England Journal of Medicine

Boston, MA

Adjunct Investigator, National Institute of Aging

National Institutes of Health

Bethesda, MD

Dennis L. Kasper, MD

William Ellery Channing Professor of Medicine

Professor of Microbiology and Molecular Genetics

Harvard Medical School

Director, Channing Laboratory, Department of Medicine

Brigham and Women's Hospital

Boston, MA

J. Larry Jameson, MD, PhD

Robert G. Dunlap Professor of Medicine

Dean, University of Pennsylvania School of Medicine

Executive Vice-President of the University of

Pennsylvania for the Health System

Philadelphia, PA

Anthony S. Fauci, MD

Chief, Laboratory of Immunoregulation

Director, National Institute of Allergy and Infectious

Diseases, National Institute of Health

Bethesda, MD

Stephen L. Hauser, MD

Robert A. Fishman Distinguished Professor and Chairman

Department of Neurology

University of California, San Francisco

San Francisco, CA

Joseph Loscalzo, MD, PhD

Hersey Professor of the Theory and Practice of Medicine

Harvard Medical School

Chairman,Department of Medicine

Physician-in-Chief, Brigham and Women's Hospital

Boston, MA

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Table of Contents

(Chapters beginning with "e" are to be found on the DVD)

Summaries of Chapters e1 to e57




1. The Practice of Medicine, The Editors

2. Global Issues in Medicine, Jim Yong Kim, Paul Farmer, and Joseph Rhatigan

3. Decision-Making in Clinical Medicine, Daniel B. Mark, John B. Wong

4. Screening and Prevention of Disease, Gary J. Martin

5. Principles of Clinical Pharmacology, Dan M. Roden

6. Women's Health, Andrea Dunaif

7. Medical Disorders During Pregnancy, Robert L. Barbieri and John T. Repke

8. Medical Evaluation of the Surgical Patient, Wei C. Lau, Kim A. Eagle

9. Palliative and End-of-Life Care, Ezekiel J. Emanuel

10. The Safety and Quality of Health Care, David W. Bates

e1. Primary Care in Low- and Middle-Income Countries, Tim Evans, Kumanan Rasanathan

e2. Complementary, Alternative, and Integrative Medicine, Josephine P. Briggs, Stephen E. Straus

e3. The Economics of Medical Care, Joseph P. Newhouse

e4. Racial and Ethnic Disparities in Health Care, Joseph R. Betancourt, Alexander R. Green

e5. Ethical Issues in Clinical Medicine, Bernard Lo

e6. Neoplasia During Pregnancy, Dan L. Longo


Section 1: Pain

11. Pain: Pathophysiology and Management, James P. Rathmell, Howard L. Fields

12. Chest Discomfort, Thomas H. Lee

13. Abdominal Pain, William Silen

14. Headache, Peter J. Goadsby, Neil H. Raskin

15. Back and Neck Pain, John W. Engstrom, Richard A. Deyo

Section 2: Alterations in Body Temperature

16. Fever and Hyperthermia, Charles A. Dinarello, Reuven Porat

17.Fever and Rash, Elaine T. Kaye, Kenneth M. Kaye

e7. Atlas of Rashes Associated with Fever, Kenneth M. Kaye, Elaine T. Kaye

18. Fever of Unknown Origin, Jeffrey A. Gelfand, Michael V. Callahan

19. Hypothermia and Frostbite, Daniel F. Danzl

Section 3: Nervous System Dysfunction

20. Syncope, Roy Freeman

21. Dizziness and Vertigo, Mark F. Walker, Robert B. Daroff

22. Weakness and Paralysis, Michael J. Aminoff

23. Numbness, Tingling, and Sensory Loss, Michael J. Aminoff, Arthur K. Asbury

24. Gait and Balance Disorders, Lewis Sudarsky

e8. Video Library of Gait Disorders, Gail Kang, Nicholas B. Galifianakis, Michael Geschwind

25. Confusion and Delirium, S. Andrew Josephson, Bruce L. Miller

26. Aphasia, Memory Loss, and Other Focal Cerebral Disorders, M.-Marsel Mesulam

e9. Memory Loss, Bruce L. Miller, Indre V. Viskontas

e10. Primary Progressive Aphasia, Memory Loss, and Other Focal Cerebral Disorders, Maria Luis Gorno-Tempini, Jeninfer Ogar, Joel Kramer, Bruce Miller, Gil Rabinovici, and Maria Carmela Tartaglia

27. Sleep Disorders, Charles A. Czeisler, John W. Winkelman, Gary S. Richardson

Section 4: Disorders of Eyes, Ears, Nose, and Throat

28. Disorders of the Eye, Jonathan C. Horton

e11. Video Library of Neuro-Ophthalmology, Shirley H. Wray

29. Disorders of Smell and Taste, Richard L. Doty, Steven M. Bromley

30. Disorders of Hearing, Anil K. Lalwani

31. Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Tract Infections, Michael A. Rubin, Larry C. Ford, Ralph Gonzales

32. Oral Manifestations of Disease, Samuel C. Durso

e12. Atlas of Oral Manifestations of Disease, Samuel C. Durso, Janet A. Yellowitz

Section 5: Alterations in Circulatory and Respiratory Functions

33. Dyspnea, Richard M. Schwartzstein

34. Cough and Hemoptysis, Patricia Kritek, Christopher Fanta

35. Hypoxia and Cyanosis, Joseph Loscalzo

36. Edema, Eugene Braunwald, Joseph Loscalzo

e13. Approach to the Patient with a Heart Murmur, Patrick T. O'Gara, Joseph Loscalzo

37. Palpitations, Joseph Loscalzo

Section 6: Alterations in Gastrointestinal Function

38. Dysphagia, Ikuo Hirano, Peter J. Kahrilas

39. Nausea, Vomiting, and Indigestion, William L. Hasler

40. Diarrhea and Constipation, Michael Camilleri, Joseph A. Murray

41. Gastrointestinal Bleeding, Loren Laine

42. Jaundice, Daniel S. Pratt, Marshall M. Kaplan

43. Abdominal Swelling and Ascites, Kathleen E. Corey, Lawrence S. Friedman

Section 7: Alterations in Renal and Urinary Tract Function

44. Azotemia and Urinary Abnormalities, Julie Lin, Bradley M. Denker

e14. Atlas of Urinary Sediments and Renal Biopsies, Agnes B. Fogo, Eric G. Neilson

45. Fluid and Electrolyte Disturbances, David B. Mount

e15. Fluid and Electrolyte Imbalances and Acid-Base Disturbances: Case Examples, David B. Mount, Thomas D. Dubose, Jr.

46. Hypercalcemia and Hypocalcemia, Sundeep Khosla

47. Acidosis and Alkalosis, Thomas D. Dubose, Jr.

Section 8: Alterations in Sexual Function and Reproduction

48. Sexual Dysfunction, Kevin T. McVary

49. Hirsutism and Virilization, David A. Ehrmann

50. Menstrual Disorders and Pelvic Pain, Janet E. Hall

Section 9: Alterations in the Skin

51. Approach to the Patient with a Skin Disorder, Thomas J. Lawley, Kim B. Yancey

52. Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders, Leslie P. Lawley, Calvin O. McCall, Thomas J. Lawley

53. Skin Manifestations of Internal Disease, Jean L. Bolognia, Irwin M. Braverman (ed. Fauci)

54. Immunologically Mediated Skin Diseases, Kim B. Yancey, Thomas J. Lawley

55. Cutaneous Drug Reactions, Kanada Shinkai, Jean-Claude Roujeau, Robert S. Stern, Bruce U. Wintroub

56. Photosensitivity and Other Reactions to Light, Alexander G. Marneros, David R. Bickers

e16. Atlas of Skin Manifestations of Internal Disease, Thomas J. Lawley, Robert A. Swerlick

Section 10: Hematologic Alterations

57. Anemia and Polycythemia, John W. Adamson, Dan L. Longo

58. Bleeding and Thrombosis, Barbara Konkle

59. Enlargement of Lymph Nodes and Spleen

60. Disorders of Granulocytes and Monocytes, Steven M. Holland, John I. Gallin

e17. Atlas of Hematology and Analysis of Peripheral Blood Smears, Dan L. Longo


61. Principles of Human Genetics, J. Larry Jameson, Peter Kopp

62. Chromosome Disorders, Stuart Schwartz, Terry Hassold

63. The Practice of Genetics in Clinical Medicine, Susan Miesfeldt, J. Larry Jameson

e18. Mitochondrial DNA and Heritable Traits and Diseases, Karl Skorecki, Hanna Mandel

64. The Human Microbiome, Jeffrey I. Gordon, Rob Knight

e19. Systems Biology in Health and Disease, Joseph Loscalzo


65. Stem Cell Biology, Minoru S. H. Ko

66. Hematopoietic Stem Cells, David T. Scadden, Dan L. Longo

67. Applications of Stem Cell Biology in Clinical Medicine, John A. Kessler

68. Gene Therapy in Clinical Medicine, Katherine A. High

69. Tissue Engineering, David M. Hoganson, Howard I. Pryor, II, Joseph P. Vacanti


70. World Demography of Aging, Richard Suzman

71. The Biology of Aging, George M. Martin

72. Clinical Problems of Aging, Luigi Ferrucci, Stephanie Studenski


73. Nutrient Requirements and Dietary Assessment, Johanna Dwyer

74. Vitamin and Trace Mineral Deficiency and Excess, Robert M. Russell, Paolo M. Suter

75. Malnutrition and Nutritional Assessment, Douglas C. Heimburger

76. Enteral and Parenteral Nutrition Therapy, Bruce R. Bistrian, David F. Driscoll

77. Biology of Obesity, Jeffrey S. Flier, Eleftheria Maratos-Flier

78. Evaluation and Management of Obesity, Robert F. Kushner

79. Eating Disorders, B. Timothy Walsh, Evelyn Attia

80. Involuntary Weight Loss, Russell G. Robertson, J. Larry Jameson


Section 1: Neoplastic Disorders

81. Approach to the Patient with Cancer, Dan L. Longo

82. Prevention and Early Detection of Cancer, Jennifer M. Croswell, Otis W. Brawley, Barnett S. Kramer

83. Cancer Genetics, Pat J. Morin, Jeffrey M. Trent, Francis S. Collins, Bert Vogelstein

84. Cancer Cell Biology and Angiogenesis, Robert G. Fenton, Dan L. Longo

85. Principles of Cancer Treatment, Edward A. Sausville, Dan L. Longo

86. Infections in Patients with Cancer, Robert Finberg

87. Cancer of the Skin, Walter J. Urba, Carl V. Washington, Hari Nadiminti

88. Head and Neck Cancer, Everett E. Vokes

89. Neoplasms of the Lung, Leora Horn, William Pao, David H. Johnson

90. Breast Cancer, Marc E. Lippman

91. Gastrointestinal Tract Cancer, Robert J. Mayer

92. Tumors of the Liver and Biliary Tree, Brian I. Carr

93. Pancreatic Cancer, Irene Chong, David Cunningham

94. Bladder and Renal Cell Carcinomas, Howard I. Scher, Robert J. Motzer

95. Benign and Malignant Diseases of the Prostate, Howard I. Scher

96. Testicular Cancer, Robert J. Motzer, George J. Bosl

97. Gynecologic Malignancies, Michael V. Seiden

98. Soft Tissue and Bone Sarcomas and Bone Metastases, Shreyaskumar R. Patel, Robert S. Benjamin

99. Carcinoma of Unknown Primary, Gauri R. Varadhachary, James L. Abbruzzese

100. Paraneoplastic Syndromes: Endocrinologic/Hematologic, J. Larry Jameson, Dan L. Longo

101. Paraneoplastic Neurologic Syndromes, Josep Dalmau, Myrna R. Rosenfeld

e20. Thymoma, Dan L. Longo

102. Late Consequences of Cancer and Its Treatment, Carl E. Freter, Dan L. Longo

Section 2: Hematopoietic Disorders

103. Iron Deficiency and Other Hypoproliferative Anemias, John W. Adamson

104. Disorders of Hemoglobin, Edward J. Benz, Jr.

105. Megaloblastic Anemias, A. Victor Hoffbrand

106. Hemolytic Anemias and Anemia Due to Acute Blood Loss, Lucio Luzzatto

107. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes, Neal S. Young

108. Polycythemia Vera and Other Myeloproliferative Diseases, Jerry L. Spivak

109. Acute and Chronic Myeloid Leukemia, Meir Wetzler, Guido Marcucci, and Clara D. Bloomfield

110. Malignancies of Lymphoid Cells, Dan L. Longo

e21. Less Common Hematologic Malignancies, Dan L. Longo

111. Plasma Cell Disorders, Nikhil C. Munshi, Dan L. Longo, Kenneth C. Anderson

112. Amyloidosis, David C. Seldin, Martha Skinner

113. Transfusion Biology and Therapy, Jeffery S. Dzieczkowski, Kenneth c. Anderson

114. Hematopoietic Cell Transplantation, Frederick R. Appelbaum

Section 3: Disorders of Hemostasis

115. Disorders of Platelets and Vessel Wall, Barbara Konkle

116. Coagulation Disorders, Valder R. Arruda, Katherine A. High

117. Arterial and Venous Thrombosis, Jane E. Freedman, Joseph Loscalzo

118. Antiplatelet Anticoagulant and Fibrinolytic Drugs, Jeffrey I. Weitz


Section 1: Basic Considerations in Infectious Diseases

119. Introduction to Infectious Diseases: Host-Pathogen Interactions, Lawrence C. Madoff, Dennis L. Kasper

120. Molecular Mechanisms of Microbial Pathogenesis, Gerald B. Pier

121. Approach to the Acutely Ill Infected Febrile Patient, Tamar F. Barlam, Dennis L. Kasper

122. Immunization Principles and Vaccine Use, Anne Schuchat, Lisa A. Jackson

123. Health Recommendations for International Travel, Jay S. Keystone, Phyllis E. Kozarsky

e22. Laboratory Diagnosis of Infectious Diseases, Alexander J. McAdam, Andrew B. Onderdonk

Section 2: Clinical Syndromes: Community-Acquired Infections

124. Infective Endocarditis, Adolf W. Karchmer

125. Infections of the Skin, Muscles, and Soft Tissues, Dennis L. Stevens

126. Osteomyelitis, Alan D. Tice

127. Intraabdominal Infections and Abscesses, Miriam J. Baron, Dennis L. Kasper

128. Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning, Regina C. LaRocque, Edward T. Ryan, Stephen B. Calderwood

129. Clostridium difficile Infection, Including Pseudomembranous Colitis, Dale N. Gerding, Stuart Johnson

130. Sexually Transmitted Infections: Overview and Clinical Approach, Jeanne M. Marrazzo, King K. Holmes

e23. Infectious Complications of Burns, Lawrence C. Madoff, Florencia Pereyra

e24. Infectious Complications of Bites, Lawrence C. Madoff, Florencia Pereyra

Section 3: Clinical Syndromes: Health Care-Associated Infections

131. Health Care-Associated Infections, Robert A. Weinstein

132. Infections in Transplant Recipients, Robert Finberg, Joyce Fingeroth

Section 4: Approach to Therapy for Bacterial Diseases,

133. Treatment and Prophylaxis of Bacterial Infections, Gordon L. Archer, Ronald E. Polk

Section 5: Diseases Caused by Gram-Positive Bacteria,

134. Pneumococcal Infections, David Goldblatt, Katherine L. O'Brien

135. Staphylococcal Infections, Franklin D. Lowy

136. Streptococcal Infections, Michael R. Wessels

137. Enterococcal Infections, Cesar A. Arias, Barbara E. Murray

138. Diphtheria and Other Infections Caused by Corynebacteria and Related Species, William R. Bishai, John R. Murphy

139. Listeria monocytogenes Infections, Elizabeth L. Hohmann, Daniel A. Portnoy

140. Tetanus, C. Louise Thwaites, Lam Minh Yen

141. Botulism, Jeremy Sobel, Susan Maslanka

142. Gas Gangrene and Other Clostridial Infections, Amy E. Bryant, Dennis L. Stevens

Section 6: Diseases Caused by Gram-Negative Bacteria

143. Meningococcal Infections, Andrew J. Pollard

144. Gonococcal Infections, Sanjay Ram, Peter A. Rice

145. Haemophilus and Moraxella Infections, Timothy F. Murphy

146. Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria, Tamar F. Barlam, Dennis L. Kasper

147. Legionella Infections, Miguel Sabria, Victor L. Yu

148. Pertussis and Other Bordetella Infections, Scott A. Halperin

149. Diseases Caused by Gram-Negative Enteric Bacilli, Thomas A. Russo, James R. Johnson

150. Acinetobacter Infections, David L. Paterson, Anton Y. Peleg

151. Helicobacter pylori Infections, John C. Atherton, Martin J. Blaser

152. Infections Due to Pseudomonas Species and Related Organisms, Reuben Ramphal

153. Salmonellosis, David A. Pegues, Samuel I. Miller

154. Shigellosis, David A. Pegues, Samuel I. Miller

155. Infections Due to Campylobacter

and Related Organisms, Martin J. Blaser

156. Cholera and Other Vibrioses, Matthew K. Waldor, Edward T. Ryan

157. Brucellosis, Michael J. Corbel, Nicholas J. Beeching

158. Tularemia, Richard F. Jacobs, Gordon E. Schutze

159. Plague and Other Yersinia Infections, Michael B. Prentice

160. Bartonella Infections, Including Cat-Scratch Disease, Michael Giladi, Moshe Ephros

161. Donovanosis, Nigel O'Farrell

Section 7: Miscellaneous Bacterial Infections

162. Nocardiosis, Gregory A. Filice

163. Actinomycosis, Thomas A. Russo

164. Infections Due to Mixed Anaerobic Organisms, Dennis L. Kasper, Ronit Cohen-Poradosu

Section 8: Mycobacterial Diseases

165. Tuberculosis, Mario C. Raviglione, Richard J. O'Brien

166. Leprosy, Robert H. Gelber

167. Nontuberculous Mycobacterial Infections, Steven M. Holland

168. Antimycobacterial Agents, Max R. O'Donnell, Jussi J. Saukkonen

Section 9: Spirochetal Diseases

169. Syphilis, Sheila A. Lukehart

170. Endemic Treponematoses, Sheila A. Lukehart

171. Leptospirosis, Joseph M. Vinetz

172. Relapsing Fever, Mark S. Dworkin

173. Lyme Borreliosis, Allen C. Steere

Section 10: Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae

174. Rickettsial Diseases, David H. Walker, J. Stephen Dumler, Thomas Marrie

175. Infections Due to Mycoplasmas, R. Doug Hardy

176. Chlamydial Infections, Charlotte A. Gaydos, Thomas C. Quinn

Section 11: Viral Diseases: General Considerations

177. Medical Virology, Fred Wang, Elliott Kieff

178. Antiviral Chemotherapy, Excluding Antiretroviral Drugs, Lindsey R. Baden, Raphael Dolin

Section 12: Infections Due to DNA Viruses

179. Herpes Simplex Virus Infections, Lawrence Corey

180. Varicella-Zoster Virus Infections, Richard J. Whitley

181. Epstein-Barr Virus Infections, Including Infectious Mononucleosis, Jeffrey I. Cohen

182. Cytomegalovirus and Human Herpesvirus Types 6,7, and 8, Martin S. Hirsch

183. Molluscum Contagiosum, Monkeypox, and Other Poxvirus Infections, Fred Wang

184. Parvovirus Infections, Kevin E. Brown

185. Human Papillomavirus Infections, Richard C. Reichman

Section 13: Infections Due to DNA and RNA Respiratory Viruses

186. Common Viral Respiratory Infections, Raphael Dolin

187. Influenza, Raphael Dolin

Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses

188. The Human Retroviruses, Dan L. Longo

189. Human Immunodeficiency Virus Disease: AIDS and Related Disorders, Anthony S. Fauci, H. Clifford Lane

Section 15: Infections Due to RNA Viruses

190. Viral Gastroenteritis, Umesh D. Parashar, Roger I. Glass

191. Enteroviruses and Reoviruses, Jeffrey I. Cohen

192. Measles (Rubeola), William J. Moss

193. Rubella (German Measles), Laura A. Zimmerman, Susan E. Reef

194. Mumps, Steven Rubin, Kathryn M. Carbone

195. Rabies and Other Rhabdovirus Infections, Alan C. Jackson

196. Infections Caused by Arthropod- and Rodent-Borne Viruses, Clarence J. Peters

197. Ebola and Marburg Viruses, Clarence J. Peters

Section 16: Fungal Infections

198. Diagnosis and Treatment of Fungal Infections, John E. Edwards, Jr.

199. Histoplasmosis, Chadi A. Hage, L. Joseph Wheat

200. Coccidioidomycosis, Neiil M. Ampel

201. Blastomycosis, Stanley W. Chapman, Donna C. Sullivan

202. Cryptococcosis, Arturo Casadevall

203. Candidiasis, John E. Edwards, Jr.

204. Aspergillosis, David W. Denning

205. Mucormycosis, Brad Spellberg, Ashraf S. Ibrahim

206. Superficial Mycoses and Less Common Systemic Mycoses, Carol A. Kauffman

207. Pneumocystis Infections, A. George Smulian, Peter D. Walzer

Section 17: Protozoal and Helminthic Infections: General Considerations

e25. Laboratory Diagnosis of Parasitic Infections, Sharon L. Reed, Charles E. Davis

208. Agents Used to Treat Parasitic Infections, Thomas A. Moore

e26. Pharmacology of Agents Used to Treat Parasitic Infections, Thomas A. Moore

Section 18: Protozoal Infections

209. Amebiasis and Infection With Free-Living Amebas, Samuel L. Stanley, Jr.

210. Malaria, Nicholas J. White, Joel G. Berman

211. Babesiosis, Edouard Vannier, Jeffrey A. Gelfand

e27. Atlas of Blood Smears of Malaria and Babesiosis, Nicholas J. White, Joel G. Breman

212. Leishmaniasis, Shyam Sundar

213. Chagas' Disease and Trypanosomiasis, Louis V. Kirchhoff, Anis Rassi, Jr.

214. Toxoplasma Infections, Kami Kim, Lloyd H. Kasper

215. Protozoal Intestinal Infections and Trichomoniasis, Peter F. Weller

Section 19: Helminthic Infections

216. Trichinellosis and Other Tissue Nematode Infections, Peter F. Weller

217. Intestinal Nematode Infections, Peter F. Weller, Thomas B. Nutman

218. Filarial and Related Infections, Thomas B. Nutman, Peter F. Weller

219. Schistosomiasis and Other Trematode Infections, Adel A.F. Mahmoud

220. Cestode Infections, A. Clinton White, Jr., Peter F. Weller


221. Microbial Bioterrorism, H. Clifford Lane, Anthony S. Fauci

222. Chemical Terrorism, Charles G. Hurst, Jonathan Newmark, James A. Romano, Jr.

223. Radiation Terrorism, Zelig A. Tochner, Eli Glatstein


Section 1: Introduction to Cardiovascular Disorders

224. Basic Biology of the Cardiovascular System, Joseph Loscalzo, Peter Libby, Jonathan Epstein

225. Epidemiology of Cardiovascular Disease, Thomas A. Gaziano, J. Michael Gaziano

226. Approach to the Patient with Possible Cardiovascular Disease, Joseph Loscalzo

Section 2: Diagnosis of Cardiovascular Disorders

227. Physical Examination of the Cardiovascular System, Patrick T. O'Gara, Joseph Loscalzo

228. Electrocardiography, Ary L. Goldberger

e28. Atlas of Electrocardiography, Ary L. Goldberger

229. Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and MRI/CT Imaging, Rick A. Nishimura, Panithaya Chareonthaitawee, Matthew Martinez

e29. Atlas of Noninvasive Cardiac Imaging, Rick A. Nishimura, Panithya Chareonthaitawee, Matthew Martinez

230. Diagnostic Cardiac Catheterization and Coronary Angiography, Jane A. Leopold, David P. Faxon

Section 3: Disorders of Rhythm

231. Principles of Electrophysiology, David D. Spragg, Gordon F. Tomaselli

232. The Bradyarrhythmias, Gordon F. Tomaselli

233. The Tachyarrhythmias, Francis Marchlinski

e30. Atlas of Cardiac Arrhythmias, Ary L. Golberger

Section 4: Disorders of the Heart

234. Heart Failure and Cor Pulmonale, Douglas L. Mann, Murali Chakinala

235. Cardiac Transplantation and Prolonged Assisted Circulation, Sharon A. Hunt, Hari R. Mallidi

236. Congenital Heart Disease in the Adult, John S. Child, Jamil Aboulhosn

237. Valvular Heart Disease, Patrick O'Gara, Joseph Loscalzo

238. Cardiomyopathy and Myocarditis, Lynne Warner Stevenson, Joseph Loscalzo

239. Pericardial Disease, Eugene Braunwald

240. Tumors and Trauma of the Heart, Eric H. Awtry, Wilson S. Colucci

e31. Cardiac Manifestations of Systemic Disease, Eric H. Awtry, Wilson S. Colucci

Section 5: Vascular Disease

241. The Pathogenesis, Prevention, and Treatment of Atherosclerosis, Peter Libby

e32. Atlas of Atherosclerosis, Peter Libby

242. The Metabolic Syndrome, Robert H. Eckel

243. Ischemic Heart Disease, Elliott M. Antman, Andrew P. Selwyn, Joseph Loscalzo

244. Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction, Christopher P. Cannon

245. ST-Segment Elevation Myocardial Infarction, Elliott M. Antman, Joseph Loscalzo

246. Percutaneous Coronary Interventions and Other Interventional Procedures, David P. Faxon, Deepak L. Bhatt

e33. Atlas of Percutaneous Revascularization, Jane A. Leopold, Deepak L. Bhatt, David P. Faxon

247. Hypertensive Vascular Disease, Theodore A. Kotchen

248. Diseases of the Aorta, Mark A. Creager, Joseph Loscalzo

249. Vascular Diseases of the Extremities, Mark A. Creager, Joseph Loscalzo

250. Pulmonary Hypertension, Stuart Rich


Section 1: Diagnosis of Respiratory Disorders

251. Approach to the Patient With Disease of the Respiratory System, Patricia Kritek, Augustine Choi

252. Disturbances of Respiratory Function, Edward T. Naureckas, Julian Solway

253. Diagnostic Procedures in Respiratory Disease, Anne L. Fuhlbrigge, Augustine M. K. Choi

e34. Atlas of Chest Imaging, Patricia Kritek, John J. Reilly, Jr.

Section 2: Diseases of the Respiratory System

254. Asthma, Peter J. Barnes

255. Hypersensitivity Pneumonitis and Pulmonary Infiltrates With Eosinophilia, Alica K. Gerke, Gary W. Hunninghake

256. Occupational and Environmental Lung Disease, John R. Balmes, Frank E. Speizer

257. Pneumonia, Lionel A. Mandell, Richard Wunderink

258. Bronchiectasis and Lung Abscess, Rebecca M. Baron and John G. Bartlett

259. Cystic Fibrosis, Richard C. Boucher

260. Chronic Obstructive Pulmonary Disease, John J. Reilly, Jr., Edwin K. Silverman, Steven D. Shapiro

261. Interstitial Lung Diseases, Talmadge E. King, Jr.

262. Deep Venous Thrombosis and Pulmonary Thromboembolism, Samuel Z. Goldhaber

263. Disorders of the Pleura and Mediastinum, Richard W. Light

264. Disorders of Ventilation, John F. McConville, Julian Solway

265. Sleep Apnea, Neil J. Douglas

266. Lung Transplantation, Elbert P. Trulock


Section 1: Respiratory Critical Care

267. Approach to the Patient With Critical Illness, John P. Kress, Jesse B. Hall

268. Acute Respiratory Distress Syndrome, Bruce D. Levy, Augustine M.K. Choi

269. Mechanical Ventilatory Support, Bartolome R. Celli

Section 2: Shock and Cardiac Arrest

270. Approach to the Patient With Shock, Ronald V. Maier

271. Severe Sepsis and Septic Shock, Robert S. Munford

272. Cardiogenic Shock and Pulmonary Edema, Judith S. Hochman, David H. Ingbar

273. Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death, Robert J. Myerburg, Agustin Castellanos

Section 3: Neurologic Critical Care

274. Coma, Allan H. Ropper

275. Neurologic Critical Care, Including Hypoxic-Ischemic Encephalopathy, and Subarachnoid Hemorrhage, J. Claude Hemphill, III, Wade S. Smith, Daryl R. Gress

Section 4: Oncologic Emergencies

276. Oncologic Emergencies, Rasim Gucalp, Janice Dutcher


277. Cellular and Molecular Biology of the Kidney, Alfred L. George, Jr., Eric G. Neilson

278. Adaptation of the Kidney to Renal Injury, Raymond C. Harris, Eric G. Neilson

279. Acute Kidney Injury, Sushrut S. Waikar, Joseph V. Bonventre

280. Chronic Kidney Disease, Joanne M. Bargman, Karl Skorecki

281. Dialysis in the Treatment of Renal Failure, Kathleen D. Liu, Glenn M. Chertow

282. Transplantation in the Treatment of Renal Failure, Anil Chandraker, Edgar L. Milford, Mohamed H. Sayegh

283. Glomerular Diseases, Julia B. Lewis, Eric G. Neilson

284. Polycystic Kidney Disease and Other Inherited Tubular Disorders, David J. Salant, Craig E. Gordon

285. Tubulointerstitial Diseases of the Kidney, Laurence H. Beck, Jr., David J. Salant

286. Vascular Injury to the Kidney, Stephen C. Textor, Nelson Leung

287. Nephrolithiasis, John R. Asplin, Fredric L. Coe, Murray J. Favus

288. Urinary Tract Infections, Pyelonephritis, and Prostatitis, Barbara W. Trautner, Kalpana Gupta

e35. Interstitial Cystitis/Painful Bladder Syndrome, John W. Warren

289. Urinary Tract Obstruction, Julian L. Seifter


Section 1: Disorders of the Alimentary Tract

290. Approach to the Patient With Gastrointestinal Disease, William L. Hasler, Chung Owyang

291. Gastrointestinal Endoscopy, Louis Michel Wong Kee Song, Mark Topazian

e36. Video Atlas of Gastrointestinal Endoscopy, Louis Michel Wong Kee Song, Mark Topazian

292. Diseases of the Esophagus, Peter J. Kahrilas, Ikuo Hirano

293. Peptic Ulcer Disease and Related Disorders, John Del Valle

294. Disorders of Absorption, Henry J. Binder

e37. The Schilling Test, Henry J. Binder

295. Inflammatory Bowel Disease, Sonia Friedman, Richard S. Blumberg

296. Irritable Bowel Syndrome, Chung Owyang

297. Diverticular Disease and Common Anorectal Disorders, Susan L. Gearhart

298. Mesenteric Vascular Insufficiency, Susan L. Gearhart

299. Acute Intestinal Obstruction, William Silen

300. Acute Appendicitis and Peritonitis, William Silen

Section 2: Liver and Biliary Tract Disease

301. Approach to the Patient With Liver Disease, Marc Ghany, Jay H. Hoofnagle

302. Evaluation of Liver Function, Daniel S. Pratt, Marshall M. Kaplan

303. The Hyperbilirubinemias, Allan W. Wolkoff

304. Acute Viral Hepatitis, Jules L. Dienstag

305. Toxic and Drug-Induced Hepatitis, Jules L. Dienstag

306. Chronic Hepatitis, Jules L. Dienstag

307. Alcoholic Liver Disease, Mark E. Mailliard, Michael F. Sorrell

308. Cirrhosis and Its Complications, Bruce R. Bacon

e38. Atlas of Liver Biopsies, Jules L. Dienstag, Atul K. Bhan

309. Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver, Bruce R. Bacon

310. Liver Transplantation, Jules L. Dienstag, Raymond T. Chung

311. Diseases of the Gallbladder and Bile Ducts, Norton J. Greenberger, Gustav Paumgartner

Section 3: Disorders of the Pancreas

312. Approach to the Patient with Pancreatic Disease, Norton J. Greenberger, Darwin L. Conwell, Peter A. Banks

313. Acute and Chronic Pancreatitis, Norton J. Greenberger, Darwin L. Conwell, Bechien U. Wu, and Peter A. Banks


Section 1: The Immune System in Health and Disease

314. Introduction to the Immune System, Barton F. Haynes, Kelly A. Soderberg, and Anthony S. Fauci

315. The Major Histocompatibility Complex, Gerald T. Nepom

316. Primary Immune Deficiency Diseases, Alain Fischer

e39. Primary Immunodeficiencies Associated With (or Secondary to) Other Diseases, Alain Fischer

Section 2: Disorders

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Customer Reviews

Average Rating 3.5
( 5 )
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Sort by: Showing 1 – 4 of 5 Customer Reviews
  • Anonymous

    Posted April 14, 2012

    "Opening ebook"

    This says it all. It's what you would see if you attempted to open Harrison's Principles of Internal Medicine with the Nook app on an iPhone or iPad. The book opens, eventually, long after you've lost interest and moved on. By comparison, books open rapidly with the Kindle app, but Harrison's is not on Kindle. If you want Harrison's, try Inkling on the iPad.

    6 out of 6 people found this review helpful.

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  • Anonymous

    Posted April 6, 2014

    Harrison's Principles of Internal Medicine is really an exhausti

    Harrison's Principles of Internal Medicine is really an exhaustive treatise on the ever-changing subject of medicine. It deals with the subject systematically. various aspects viz. etiology, diagnosis, differential diagnosis, prognosis n prophylaxis dealt with in detail. verily it should adorn the shelf of competent physicians. a rare treasure a physician can lay his hands on

    Was this review helpful? Yes  No   Report this review
  • Anonymous

    Posted November 29, 2012



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  • Anonymous

    Posted October 31, 2013

    No text was provided for this review.

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