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In a climate where many unsubstantiated claims are made, it is essential to have access to the best evidence-based knowledge on how to extend healthy life expectancy. Researchers, healthcare practitioners, and policy makers come together annually at the International Research Center for Healthy Ageing and Longevity to discuss, debate, and exchange ideas, and the proceedings of the most recent conference is contained in the chapters of this volume.
Now, more than ever, a critical need exists for the development of appropriate policies so that aging is seen as a resource and not as an isolating and segregating experience. Solid research elucidating the processes of aging must be translated into strategies for clinical practice in order to respond to the needs of an aging population.
The full spectrum of proven and potential aging interventions including pharmaceutical, nutritional, clinical, educational, policy, complementary, preventive, and restorative means were explored at this international meeting. The topics covered in this volume include the following:
(1) Nutritional interventions in aging and age-associated disease, both diet and supplements;
(2) dementia in an aging population;
(3) the new caring — financial and asset management and substitute decision-making by and for older people;
(4) how we improve the quality of research into healthy aging;
(5) promoting balance and preventing falls in an aging population;
(6) population aging in developing countries;
(7) promoting health and well-being of the older community;
(8) hormone and metabolic interventions in aging;
(9) community attitudes and approaches towards human life extension;
(10) respecting the elders in our care;
(11) the biology of healthy aging and longevity;
(12) basic science and mechanisms of aging and longevity;
(13) sustaining optimal aging — inner strength and mutual support;
(14) wellbeing, retirement planning and expectations of the baby-boomer generation;
(15) natural and complementary approaches to age-associated disorders;
(16) psychosocial predictors of healthy aging and longevity — lessons from longitudinal studies;
(17) healthy longevity — lessons learned from the world's longest-lived people;
(18) the aging brain;
(19) baby-boomer work force participation;
(20) quality of care and quality of life for the elderly;
(21) frontiers of knowledge in biogerontology;
(22) behavioural and social interventions for healthy aging and longevity.
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Preface: Noah J. Weller, John D. Weller, and Christian J. Weller.
Part I: Biogerontology:.
1. The Science of Healthy Aging: Genes, Milieu and Chance:Suresh I. S. Rattan.
2. Pursuing the Longevity Dividend: Scientific Goals for anAging World: S. Jay Olshansky, Daniel Perry, Richard A. Miller, andRobert N. Butler.
3. Senescence Viewed Through the Lens of Comparative Biology:Bruce A. Carnes.
4. Cytomegalovirus Infection: A Driving Force in Human T cellImmunosenescence: Sven Koch, Anis Larbi, Dennis Özcelik,Rafael Solana, Cécile Gouttefangeas, Sebastian Attig, AndersWikby, Jan Strindhall, Claudio Franceschi, Graham Pawelec.
5. Transcriptional Regulation of Telomerase Activity: Roles ofthe Ets Transcription Factor Family: Julie Dwyer, He Li, Dakang Xu,and Jun-Ping Liu.
6. Potential Roles for Estrogen Regulation of TelomeraseActivity in Aging: Sharyn Bayne, Margaret E. E. Jones, He Li andJun-Ping Liu.
7. Mechanisms of Action of TGFb in Cancer: Evidence for Smad3 asa Repressor of the hTERT Gene: He Li and Jun-Ping Liu.
8. Evidence That Autophagy Is Involved in Aging and Is anEssential Part in the Anti-aging Mechanism of Caloric Restriction:Ettore Bergamini, Gabriella Cavallini, Alessio Donati and ZinaGori.
9. Age-related Changes in the Liver Sinusoidal Endothelium Are aMechanism for Dyslipidemia: David G. Le Couteur, Victoria C.Cogger, Robert S. McCuskey, Rafael de Cabo, BårdSmedsrød, Karen K Sorensen, Alessandra Warren, RobinFraser.
10. Effects of Old Age on Hepatocyte Oxygenation: RajkumarCheluvappa, Sarah N Hilmer, Sun Young Kwun, Victoria C Cogger,David G Le Couteur.
11. Comparative Analysis of Mitochondrial Genotype and Aging: J.William O. Ballard, Subhash D. Katewa, Richard G. Melvin, and GraceChan.
Part II: Clinical Perspective:.
12. Fit and Well at 80: Defying the Stereotypes of Age andIllness: Julie Byles.
13. Delaying Dementia and Nursing Home Placement: The DubboStudy of Elderly Australians over 14 Years: John McCallum, Leon A.Simons, Judith Simons, and Yechiel Friedlander.
14. Patients with Dementia and Their Carers: CharlesBridges-Webb, Belinda Giles, Catherine Speechly, Yvonne Zurynski,Navaz Hiramanek.
15. Healthy Aging: Can Clinical Trials Deliver?: Erica Bell.
16. Debating the Influence of Self-reports by People Living withChronic Disease on Healthy Aging and Longevity: Kay Price.
17. Health and Aged Care Enabled by Information Technology:Jeffrey Soar and Youngjoon Seo.
18. Healthy Aging as an Intervention to Minimize Falls Injuryamong Older People: Nancye May Peel, Helen Patricia Bartlett,Roderick John McClure.
19. Building an Infrastructure to Prevent Falls in OlderCalifornians: The Fall Prevention Center of Excellence: Debra J.Rose, Gretchen E. Alkema, In Hee Choi, Christy M. Nishita, &Jon Pynoos.
20. Age-related Changes in Strength and Somato-sensation duringMid-life Support Rationale for Targeted Preventive InterventionPrograms: Nancy L Low Choy, Sandra G Brauer, Jennifer C Nitz.
21. Living Well until You Die: Quality of Care and Quality ofLife in Palliative and Dementia Care: Neil Small.
22. Complementary and Alternative Medicine Use by OlderAustralians: Anthony L Zhang, Charlie CL Xue, Vivian Lin, David FStory.
23. Anti-Aging Medicine and the Cultural Context of Aging inAustralia : Beatriz Cardona.
Part III : Socio-cultural Perspective:.
24. Are We Getting Healthier as We Grow Older? Implications forBaby Boomer Labour Force Participation: Deborah J Schofield, MeganE Passey, Arul Earnest, Ian C Gloor, Rupendra Shrestha.
25. Independence, Wellbeing and Social Participation in an AgingPopulation: Fiona Alpass, Andy Towers, Christine Stephens, EljonFitzgerald, Brendan Stevenson, and Judith Davey.
26. Grey Nomads' in Australia: Are They a Good Model forSuccessful Aging and Health: Paul F. D. Higgs, Frances Quirk.
27. Affordable Rental Housing for Older People in Australia:What Do Older People Want?: Colleen Maria Cartwright.
28. Retirement Planning and Expectation of AustralianBabyboomers: Are They Ready?: Wendy Hunter, Wei Wang and AnthonyWorsley.
29. Age Identity, Age Perceptions, and Health: Evidence from theEnglish Longitudinal Study of Aging: Panayotes Demakakos, EdliraGjonca, and James Nazroo.
30. Community Attitudes to the Regulation of Life Extension:Mair Underwood, Helen Bartlett and Wayne Hall.
31. Тhe Еlderly in a Period of Transition: Health,Personality and Social Aspects of Adaptation: Ignat C. Petrov.
32. The Human Mosaic: Cultural Beliefs and Health ProfessionsTraining: Rosellen M. Rosich.
33. Lifestyle of the Elderly in Rural and Urban Malaysia: DorisPadmini Selvaratnam and Poo Bee Tin.
34. Healthy Aging for Caregivers: What Are Their Needs?: Tina Wuand Karen Lo.
35. Well for Life, A Way of Life: Wendi A. Kruger, Catherine E.Thompson, Rosemary A. McKenzie, Lucio Naccarella.
36. A Management Control System for the Development, Contractingand Monitoring of Services for Older People: Stephen Jacobs.
37. The New Caring: Financial Asset Management and Older People:Cheryl Tilse, Jill Wilson, Deborah Setterlund, Linda Rosenman.
38. Involving Service Users and their Carers as Equal Partnerson a Project Using Electronic Communication: Susan M Ashby, Sian EMaslin-Prothero, Amelia C Rout.
Part IV: Interventions:.
39. Nutritional Interventions in Aging and Age-associatedDiseases : George S. Roth, Donald K. Ingram, James A. Joseph.
40. From Beans to Berries and Beyond: Teamwork between PlantChemicals for Protection of Optimal Human Health: Mary AnnLila.
41. Dietary Polyunsaturated Fatty Acids and Age-related MembraneChanges in the Heart: Salvatore Pepe.
42. Dietary Influences on Cognitive Function with Aging: FromHigh Fat Diets to Healthful Eating: Matthew D Parrotta, Carol EGreenwood.
43. Combining an Antioxidant Fortified Diet with BehavioralEnrichment Leads to Cognitive Improvement and Reduced BrainPathology in Aging Canines: Strategies for Healthy Aging: ElizabethHead.
44. The Effect of Resveratrol on a Cell Model of Human Aging:Maurizio Stefani, M. Andrea Markus, Ruby C. Y. Lin, Mark Pinese,Ian W. Dawes, and Brian J. Morris.
45. Intermittent Dietary Restriction as a Practical AgingIntervention: Sandeep Sharma and Gurcharan Kaur.
46. Life Extension by Calorie Restriction in Humans: Arthur VEveritt, David G Le Couteur.
47. Caloric Restriction, the Traditional Okinawan Diet andHealthy Aging: The Diet of the World's Longest-Lived People and ItsPotential Impact on Morbidity and Lifespan: Bradley J. Willcox, D.Craig Willcox, Hidemi Todoriki, Akira Fujiyoshi, Katsuhiko Yano,Qimei He, J. David Curb, Makoto Suzuki.
48. Evidence-based Practice: Limitations and SuccessfulImplementation: Rhonda Maree Nay and Deirdre Marie AnnFetherstonhaugh