Heart Cell Communication in Health and Disease / Edition 1

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Overview

In Heart Cell Communication in Health and Disease an extensive review of different aspects of heart cell communication is presented. The book starts with the fundamental concept that cardiac cells are communicated, and then proceeds to the role of gap junctions in heart development, the molecular biology of gap junctions, the biophysics of the intercellular channels, the control of junctional conductance and the influence of gap junctions on impulse propagation.
This is the first time that a single volume has described cell communication in the normal heart and under different pathological conditions such as heart failure, coronary disease, myocardial ischemia and cardiac arrhythmias. In this way the process of cell communication is analyzed at different levels of complexity, providing the reader with a wide view of this field and its relevance to cardiology.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Stephen L. Lipsius, PhD (Loyola University Medical Center)
Description: This book presents a comprehensive review of several important aspects of heart cell communication, written by international experts in their respective fields. Starting with fundamental concepts, the book expands into the role of gap junctions in heart development; the molecular biology of gap junctions; biophysics of intercellular channels and their control; gap junctions in impulse conduction; and finally, the role of gap junctions in cardiac pathophysiology.
Purpose: The purpose is to present, in a single volume, the intricacies and complexities of cell communication in the normal heart as well as under pathological conditions. This book has most successfully achieved the editors' objectives.
Audience: Although the editors have not indicated the intended audience, I believe this book would be well suited for any student seriously interested in cell communication in the heart. This includes graduate students and established investigators interested in the physiology, biophysics, or molecular biology of cardiac function, as well as academic cardiologists.
Features: The book contains ten chapters written by international experts in their respective fields. Each chapter is comprehensive, and most are extensively referenced with up-to-date citations and illustrated with clear, informative figures. The only minor presentation flaw is that all chapters are not printed in the same font. The index is good.
Assessment: Quality and educational value are excellent. This book presents a comprehensive review of a broad range of topics related to cell communication in the heart. It provides an important resource for both students and established researchers in the field of cardiac cell communication. It is highly recommended for academic libraries, bookstores, and interested individuals.
Stephen L. Lipsius
This book presents a comprehensive review of several important aspects of heart cell communication, written by international experts in their respective fields. Starting with fundamental concepts, the book expands into the role of gap junctions in heart development; the molecular biology of gap junctions; biophysics of intercellular channels and their control; gap junctions in impulse conduction; and finally, the role of gap junctions in cardiac pathophysiology. The purpose is to present, in a single volume, the intricacies and complexities of cell communication in the normal heart as well as under pathological conditions. This book has most successfully achieved the editors' objectives. Although the editors have not indicated the intended audience, I believe this book would be well suited for any student seriously interested in cell communication in the heart. This includes graduate students and established investigators interested in the physiology, biophysics, or molecular biology of cardiac function, as well as academic cardiologists. The book contains ten chapters written by international experts in their respective fields. Each chapter is comprehensive, and most are extensively referenced with up-to-date citations and illustrated with clear, informative figures. The only minor presentation flaw is that all chapters are not printed in the same font. The index is good. Quality and educational value are excellent. This book presents a comprehensive review of a broad range of topics related to cell communication in the heart. It provides an important resource for both students and established researchers in the field of cardiac cell communication. It is highly recommended foracademic libraries, bookstores, and interested individuals.

5 Stars! from Doody
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Product Details

Table of Contents

Preface. 1. On the Syncytial Nature of Cardiac Muscle; W.C. De Mello. 2. Gap Junctions and Heart Development; R.G. Gourdie, et al. 3. Cardiovascular Gap Junction Proteins: Molecular Characterization and Biochemical Regulation; E. Beyer, et al. 4. Biophysics of Gap Junction Channels; R.D. Veenstra, Hong-Zhan Wang. 5. On the Control of Junctional Conductance; W.C. De Mello. 6. Gap Junctions and the Spread of Electrical Excitation; R. Shaw, Y. Rudy. 7. Cell to Cell Communication in the Failing Heart; W.C. De Mello. 8. Gap Junctions and Coronary Heart Disease; N.J. Severs. 9. Cellular Electrical Uncoupling During Ischemia; M. Janse, et al. 10. Gap Junctions, Cardiac Excitability and Clinical Arrhythmias; M.F. Arnsdorf, S.C. Dudley. Index.

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