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Doody's Review ServiceReviewer: Stephen L. Lipsius, PhD (Loyola University Medical Center)
Description: This book presents a comprehensive review of several important aspects of heart cell communication, written by international experts in their respective fields. Starting with fundamental concepts, the book expands into the role of gap junctions in heart development; the molecular biology of gap junctions; biophysics of intercellular channels and their control; gap junctions in impulse conduction; and finally, the role of gap junctions in cardiac pathophysiology.
Purpose: The purpose is to present, in a single volume, the intricacies and complexities of cell communication in the normal heart as well as under pathological conditions. This book has most successfully achieved the editors' objectives.
Audience: Although the editors have not indicated the intended audience, I believe this book would be well suited for any student seriously interested in cell communication in the heart. This includes graduate students and established investigators interested in the physiology, biophysics, or molecular biology of cardiac function, as well as academic cardiologists.
Features: The book contains ten chapters written by international experts in their respective fields. Each chapter is comprehensive, and most are extensively referenced with up-to-date citations and illustrated with clear, informative figures. The only minor presentation flaw is that all chapters are not printed in the same font. The index is good.
Assessment: Quality and educational value are excellent. This book presents a comprehensive review of a broad range of topics related to cell communication in the heart. It provides an important resource for both students and established researchers in the field of cardiac cell communication. It is highly recommended for academic libraries, bookstores, and interested individuals.