Heart Function in Health and Disease: Proceedings of the Cardiovascular Program sponsored by the Council of Cardiac Metabolism of the International Society and Federation of Cardiology during the Regional Meeting of the International Union of  / Edition 1

Heart Function in Health and Disease: Proceedings of the Cardiovascular Program sponsored by the Council of Cardiac Metabolism of the International Society and Federation of Cardiology during the Regional Meeting of the International Union of Physiologica / Edition 1

by Bohuslav Ost'adal
     
 

ISBN-10: 0792320522

ISBN-13: 9780792320524

Pub. Date: 09/05/2007

Publisher: Springer US

As the majority of cardiovascular deaths are related to myocardial ischemia, it is necessary to understand the various aspects of ischemic heart disease. In this regard, it is noteworthy that ischemic heart disease is commonly associated with atherosclerosis, coronary spasm, as well as thrombosis leading to the development of arrhythmias, cardiovascular cell damage,…  See more details below

Overview

As the majority of cardiovascular deaths are related to myocardial ischemia, it is necessary to understand the various aspects of ischemic heart disease. In this regard, it is noteworthy that ischemic heart disease is commonly associated with atherosclerosis, coronary spasm, as well as thrombosis leading to the development of arrhythmias, cardiovascular cell damage, myocardial infarction, cardiac hypertrophy and congestive heart failure. Furthermore, it is also important to appreciate various physiological, electrophysiological and biochemical processes in the normal heart if we are to understand their significance under pathological situations.
Heart Function in Health and Disease has been organized in five sections to provide an outline of a complex problem in a convenient manner. One section of this book is devoted to shedding light on the restructuring and ontogenic changes in the developing heart whereas in the next section some hypertrophic alterations due to chronic hypoxia are described. The third and fourth sections of this book are concerned with the regulation of cardiac channels as well as signal transduction mechanisms and cardiac electric field. The fifth section contains some pathophysiological events during the development of cardiac hypertrophy and heart failure. All of these areas encompass a significant body of new information that will be invaluable to those who work in the field of cardiovascular sciences, as well as those who treat people with heart disease.

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Product Details

ISBN-13:
9780792320524
Publisher:
Springer US
Publication date:
09/05/2007
Series:
Developments in Cardiovascular Medicine Series, #140
Edition description:
1993
Pages:
335
Product dimensions:
9.21(w) x 6.14(h) x 0.81(d)

Table of Contents

Preface
Acknowledgements
1Heart story: A view to the past3
2Postnatal growth and restructuring of mammalian hearts23
3Ontogenetic development of cardiac inotropic responsiveness31
4Activation mechanisms of cardiac muscarinic K channels47
5Multiple cyclic GMP binding proteins involved in the regulation of cardiac calcium channels61
6Participation of the Na[superscript +]-H[superscript +] exchange pathway in cardiac pathology71
7Phospholipase D: A new avenue to the phospholipid signalling pathways in the myocardium79
8Cardiac pacemaker activity: From single cells to modelling the heart93
9Physiology of the cardiac electric field111
10Modelling of the cardiac electrical field127
11The temporal behaviour of the cardiac electric field143
12Computer modelling of cardiac arrhythmias157
13Relationship between heart mass and hemoglobin/hematocrit at high altitude - Function or fallacy?185
14Functional assessment of the hypertrophic right ventricle in the rat heart193
15Chronic hypoxia-induced right ventricular enlargement: Age-dependent changes of collagenous and non-collagenous cardiac protein fractions209
16Sarcolemmal cation transport systems in rat hearts acclimatized to high altitude hypoxia, influence of 7-oxo-prostacyclin
17Effects on the heart of two forms of chronic hypoxia229
18Thyroid hormones and cardiac hypertrophy239
19Diastolic dysfunction of the heart. Pharmacological strategies for modulating calcium sequestration of the sarcoplasmic reticulum251
20Conduit coronary artery structure and function273
21Heart failure: A disease of adaptation287
22Involvement of sarcolemmal Na[superscript +]-K[superscript +] ATPase in the pathogenesis of heart disease295
23Neuroendocrine response to heart failure307
24Alterations of extracellular matrix in cardiac atrophy321

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