Heat Shock Proteins and the Cardiovascular System / Edition 1

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The first observations on heat shock proteins and the heart were made in the 1980s, and interest in these proteins has increased over the decade. In the last few years there has been an exponential growth in the number of papers published on heat shock proteins and the heart. Heat shock proteins have been implicated in a number of cardiovascular research areas including ischemia, hypertrophy, aging, and atherosclerosis, and this list is growing.
The purpose of Heat Shock Proteins and the Cardiovascular System is to give an overview of our current understanding of the heat shock proteins in the cardiovascular system, and to summarize the approaches to the study of heat shock proteins in the heart. This volume assembles results from a number of different cardiovascular fields, and provides a comprehensive review of heat shock proteins in the cardiovascular system.

The book contains black-and-white illustrations.

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Editorial Reviews

The elements of an endogenous protection systems, known in heat- shocked drosophila since the early 1960s, were first discovered in the heart in the 1980s and have since been implicated in ischemia, hypertrophy, aging, and atherosclerosis. Here 11 studies summarize the current understanding of the proteins in the cardiovascular system and the approaches to research. The topics include regulation and function, myocardial preconditioning, antioxidative enzymes, changes during cardiac hypertrophy, expression in the aging system, tumor necrosis factor-alpha and the myocardial stress response, atherogenesis, and correlations of tissue culture findings with in-vivo models of the hypoxic-ischemic brain. Annotation c. by Book News, Inc., Portland, Or.
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Product Details

  • ISBN-13: 9780792399100
  • Publisher: Springer US
  • Publication date: 5/31/1997
  • Series: Developments in Cardiovascular Medicine Series, #192
  • Edition description: 1997
  • Edition number: 1
  • Pages: 252
  • Product dimensions: 9.21 (w) x 6.14 (h) x 0.63 (d)

Table of Contents

Preface; A.A. Knowlton. 1. An Overview of the Heat Shock Proteins, Their Regulation, and Function; A.A. Knowlton. 2. Ischemia, Infarction, and HSP 70; W.H. Dillmann, R. Mestril. 3. Do Heat Shock Proteins Play a Role in Myocardial Preconditioning? R.J. Heads, D.M. Yellon. 4. Heat Shock Proteins and Antioxidative Enzymes in Myocardial Protection; R.W. Currie, J.-C.L. Plumier. 5. Changes in Heat Shock Proteins in Cardiac Hypertrophy; S. Isoyama. 6. Heat Shock Protein Expression in the Aging Cardiovascular System; N.J. Holbrook. 7. Tumor Necrosis Factor-alpha and the Myocardial Stress Response; A.A. Knowlton, et al. 8. Role of Small Heat Shock Proteins in the Cardiovascular System; H.S. Sharma. 9. Role of Small HSP Gene Expression in Myocardial Ischemia and Reperfusion; D.K. Das, N. Maulik. 10. The Influence of Heat Shock Proteins on Atherogenesis; G. Schett, et al. 11. The Stress Response in Hypoxic-Ischemic Brain: Correlation of Tissue Culture Findings with in Vivo Models; R.N. Nishimura, B.E. Dwyer. Index.
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