Hematology: Clinical Principles and Applications / Edition 4

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Featuring hundreds of full-color photomicrographs, Hematology: Clinical Principles and Applications prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells.

  • Full-color illustrations make it easier to visualize complex concepts and show what you’ll encounter in the lab.
  • Learning objectives begin each chapter, and review questions appear at the end.
  • Instructions for lab procedures include sources of possible errors along with comments.
  • Case studies provide opportunities to apply hematology concepts to real-life scenarios.
  • Hematology instruments are described, compared, and contrasted.
  • Coverage of hemostasis and thrombosis includes the development and function of platelets, the newest theories of normal coagulation, and clear discussions of platelet abnormalities and disorders of coagulation.
  • A bulleted summary of important content appears at the end of every chapter.
  • A glossary of key terms makes it easy to find and learn definitions.
  • Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference.
  • Respected editors Bernadette Rodak, George Fritsma, and Elaine Keohane are well known in the hematology/clinical laboratory science world.
  • Student resources on the companion Evolve website include the glossary, weblinks, and content updates.
  • New content is added on basic cell biology and etiology of leukocyte neoplasias.
  • Updated Molecular Diagnostics chapter keeps you current on techniques being used in the lab.
  • Simplified hemostasis material ensures that you can understand this complex and important subject.
  • Coverage of morphologic alteration of monocytes/macrophages is condensed into a table, as the disorders in this grouping are more of a biochemical nature with minimal hematologic evidence.
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Editorial Reviews

From The Critics
Reviewer: Valerie L. Ng, PhD MD(Alameda County Medical Center/Highland Hospital)
Description: This is the second edition of a comprehensive textbook covering all aspects of hematology and hemostasis. The first edition was published in 1995.
Purpose: The purpose is to provide a comprehensive hematology/hemostasis textbook for clinical laboratory scientist (CLS) students, practicing CLSs, medical students, and residents. The intent of this updated edition is to provide the information in shorter, more manageable, and user-friendly chapters.
Audience: This book would appeal to clinical laboratory scientist students and practitioners, medical students desiring more in-depth information on the performance of clinical hematology and hemostasis testing, and residents early in their training (because of the relative lack of clinical correlation in this book as compared with standard medical textbooks).
Features: "This book is divided into 11 major areas, each containing multiple small chapters. Each chapter follows a standard and extremely useful format — objectives are clearly outlined at the beginning of each chapter, a case study follows and emphasizes the main teaching points, then the relevant text ensues, followed by a summary of the chapter ("chapter at a glance"), and ending with self-assessment review questions. This thoughtful layout assures that the reader stays focused on the major learning points and has a chance to review targeted areas prior to taking the self-exam. The text is concise and reads easily. The collection of photos and photomicrographs in this book is breathtaking in its depth and breadth; such a broad range of depicted clinical hematological disorders is rarely found in a single book. This book would be worth the price for the pictures alone! I really liked the section on hematology automation — not a common feature in standard medical hematology books, but absolutely essential for current CLS training programs. Finally, the book is physically very attractive, with nice use of color to emphasize and reinforce various teaching points. "
Assessment: This is a great book for CLS students and practitioners. I would highly recommend it for any CLS training program.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781437706925
  • Publisher: Elsevier Health Sciences
  • Publication date: 3/4/2011
  • Edition description: New Edition
  • Edition number: 4
  • Pages: 880
  • Sales rank: 623,637
  • Product dimensions: 8.70 (w) x 11.10 (h) x 1.50 (d)

Table of Contents

Part I: Introduction to Hematology 1. An Overview of Clinical Laboratory Hematology 2. Safety in the Hematology Laboratory 3. Specimen Collection 4. Care and Use of the Microscope 5. Quality Assurance in Hematology and Hemostasis Testing Part II: Hematopoiesis and Blood Cell Physiology 6. Cellular Structure and Function 7. Hematopoiesis 8. Erythrocyte Production and Destruction 9. Energy Metabolism and Membrane Physiology of the Erythrocyte 10. Hemoglobin Metabolism 11. Iron Metabolism 12. Leukocyte Development, Kinetics, and Function 13. Platelet Production, Structure, and Function Part III: Routine Laboratory Evaluation of Blood Cells 14. Routine and Point of Care Testing in Hematology: Manual and Semi-Automated Methods 15. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count 16. Bone Marrow Collection and Examination 17. Hematologic Body Fluid Examination Part IV: Hematopathology: Erythrocyte Disorders 18. Anemias: Red Blood Cell Morphology and Approach to Diagnosis 19. Disorders of Iron and Heme Metabolism 20. Anemias Caused by Defects of DNA Metabolism 21. Bone Marrow Failure 22. Introduction to Increased Erythrocyte Destruction 23. Intrinsic Defects Leading to Increased Erythrocyte Destruction 24. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Nonimmune Causes 25. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Immune Causes 26. Hemoglobinopathies: Structural Hemoglobin Defects 27. Thalassemias: Quantitative Hemoglobin Defects Part V: Leukocyte Disorders 28. Non-Malignant Leukocyte Disorders 29. Introduction to Leukocyte Neoplasms 30. Cytochemistry 31. Cytogenetics 32. Molecular Diagnostics in the Hematology Laboratory 33. Flow Cytometric Analysis of Hematologic Disorders 34. Myeloproliferative Disorders 35. Myelodysplastic Syndromes 36. Acute Leukemias 37. Lymphomas and Chronic Lymphocytic Leukemias Part VI: Hematology in Selected Populations 38. Pediatric and Geriatric Hematology Part VII: Cell Counting Automation 39. Automated Cell Counting Instrumentation Part VIII: Hemostasis and Thrombosis 40. Normal Hemostasis and Coagulation 41. Hemorrhagic Coagulation Disorders 42. Thrombosis Risk Testing 43. Thrombocytopenia and Thrombocytosis 44. Qualitative Disorders of Platelets and Vasculature 45. Laboratory Evaluation of Hemostasis 46. Monitoring Anticoagulant Therapy 47. Coagulation Instrumentation

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