Hemostasis and Stroke / Edition 1

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Overview

Hemostasis and Stroke presents an exciting and new understanding of current investigations and applications in stroke therapy. Although research in stroke, hematology, and related fields has made enormous progress in the last decade, stroke still remains one of the leading causes of death today. To achieve an interdisciplinary approach to current research and practice in the management of thrombosis of cerebrovascular disorders, scientists and clinicans worldwide met in Lübeck, Germany, in May 1993 for an International Symposium on Hemostasis and Stroke. This book represents the proceedings of the symposium. It also summarizes the results of recent stroke prevention trials, including critical reviews on current recommendations of acetylsalicyclic acid and the usefulness of ticlopidine. In addition, animal models of experimental cerebral ischemia are viewed under their possible application for research in embolic stroke.

This book contains black-and-white illustrations.

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Editorial Reviews

Cathy M. Helgason
This book presents the contents of an international symposium on thrombosis and stroke held in Lubech, Germany, in May 1993. As such, it is the first of its kind. The purpose is to present a current view of clinical and basic science aspects of thrombosis and stroke that will lead to better diagnosis and treatment. The book fulfills its purpose. The audience is all physicians treating and diagnosing patients with stroke. Cardiologists may also gain insight into aspects of coronary thrombosis from reading this book. The presentations are by experts in the field of hemostasis and stroke. The book is nicely illustrated, and the references are current and relevant. This publication is timely in its appearance and addresses the cross-section of major issues involved in potential thrombotic mechanisms of stroke. It should be useful to all involved in the diagnosis and treatment of patients with stroke and to those involved in research in this area. It is an excellent addition to the literature on the epidemiology, treatment, and etiology/pathogenesis assessment of cerebrovascular disease.
From The Critics
Reviewer:Cathy M. Helgason, MD (University of Illinois at Chicago College of Medicine)
Description:This book presents the contents of an international symposium on thrombosis and stroke held in Lubech, Germany, in May 1993. As such, it is the first of its kind.
Purpose:The purpose is to present a current view of clinical and basic science aspects of thrombosis and stroke that will lead to better diagnosis and treatment. The book fulfills its purpose.
Audience:The audience is all physicians treating and diagnosing patients with stroke. Cardiologists may also gain insight into aspects of coronary thrombosis from reading this book. The presentations are by experts in the field of hemostasis and stroke.
Features:The book is nicely illustrated, and the references are current and relevant.
Assessment:This publication is timely in its appearance and addresses the cross-section of major issues involved in potential thrombotic mechanisms of stroke. It should be useful to all involved in the diagnosis and treatment of patients with stroke and to those involved in research in this area. It is an excellent addition to the literature on the epidemiology, treatment, and etiology/pathogenesis assessment of cerebrovascular disease.
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Product Details

  • ISBN-13: 9780849376504
  • Publisher: CRC Press
  • Publication date: 3/24/1994
  • Edition number: 1
  • Pages: 176
  • Product dimensions: 0.70 (w) x 1.00 (h) x 0.60 (d)

Table of Contents

Preface: Toward the Pathogenesis of Thrombotic Disorders (C.M. Kessler and A. Rosengart). Thrombosis and Cerebrovascular Disease-Then, Now, and Tomorrow (L.R. Caplan). Platelet Activation in Vascular Disease (N. Murphy and D.J. Fitzgerald). Coagulation Markers in Acute Stroke (W.M. Feinberg). Coagulation Factors and Risk of Stroke (C. Gustafsson). Elevated Plasma Levels of Haemostatic Markers Indicating a Prethrombotic State in Nonrheumatic Atrial Fibrillation (R. Mitusch, M. Garbe, H.J. Siemens, T. Wagner, A. Sheikhzadeh, and K.W. Diederich). Jugular Venous Blood Hemostasis and Cerebrospinal Fluid Hemostatic Pathways in Stroke (U. Noormaa, H. Vadi, and A. Tikk). Models of Focal Brain Ischemia (J.H. Garcia and G.J. Del Zoppo). Therapeutic Approaches for Arterial Thrombosis (S.R. Hanson and L.A. Harker). Suppression of Thrombus Formation in Vitro and in Vivo by Thromboxane Synthetase Inhibition Combined with Endoperoxide/Thromboxane Receptor Antagonism (T.H. Müller, B.D. Guth, H. Weisenberger, and R. Soyka). Central Nervous System Involvement in Systemic Lupus Erythematosus and Cardiolipin Antibodies (M. Sailer, K. Wildhagen, C. Ehrenheim, H. Deicher, and J. Haas). The Influence of Leukocytes on Coagulation and Its Potential Significance in Cerebral Ischemia (A. Grau, T. Graf, and W. Hacke). The Relationship Between Early Fatality and Stress Hyperglycemia in Acute Stroke (S. Öztürk, T. Duman, and Sabahat Gürçay). Serotonin Antagonists Naftidrofuryl in the Treatment of Atherosclerotic Carotid Artery Disease (A. Rosengart, Y. Guo, A. Jahn, and C.M. Kessler). Clinical Trials of Platelet Inhibitors: Aspirin Dosis and Clinical Impact of Ticlopidine (H.C. Diener and C. Weiler). Clinical Trials with Low Dose Aspirin (B. Norrving). From European Stroke Prevention Study 1 (ESPS 1) to European Stroke Prevention Study 2 (ESPS 2) (A. Lowenthal). Dose-Dependent Effects of the Platelet Inhibitor Acetylsalicyclic Acid (A. Haass). Molecular Mechanism and Clinical Aspects of Heparin Treatment (G. Pindur, H. Kiesewetter, S. Mörsdorf, P. Scheffler, B. Wagner, H. Ruhl, and E. Wenzel). Anticoagulation in Stroke (P. Marx and S. Blum). Ischemic Cerebral Infarctions as a Sequel of Antineoplastic-Agents-Therapy (C. Klötzsch and P. Berlit). Index.

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