Hepatitis C Virus Disease: Immunobiology and Clinical Applications / Edition 1

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Overview

Despite numerous hepatitis C virus infection studies, its pathogenesis and medical treatment have not been fully explained. This comprehensive volume, written by experts in the field, covers the most recent advances in the study of HCV, moving from basic research to clinical applications. The first chapters of this volume analyze the full spectrum of immune responses to HCV. The volume also includes contributions that explain the state of the art in IFN-alpha treatment of HCV patients.

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Product Details

  • ISBN-13: 9780387713755
  • Publisher: Springer New York
  • Publication date: 11/28/2007
  • Edition description: 2008
  • Edition number: 1
  • Pages: 308
  • Product dimensions: 6.30 (w) x 9.30 (h) x 0.80 (d)

Table of Contents


Innate Immunity in Type C Hepatitis   Tetsuo Takehara   Norio Hayashi     1
Mechanisms of Interferon Action and Resistance in Chronic Hepatitis C Virus Infection: Lessons Learned from Cell Culture Studies   Srikanta Dash   Sidhartha Hazari   Robert F Garry   Fredric Regenstein     16
Immunological Parameters Influencing Adaptive Immune Responses to the Hepatitis C Virus   Patrick Bertolino   Geoffrey W. McCaughand   David G. Bowen     39
Immune Responses Against the Hepatitis C Virus and the Outcome of Therapy   Paul Klenerman   Eleanor Barnes     71
Other Microbial Components Associated with Hepatitis C Virus Infection: Their Effects on Interferon- [alpha]/Ribavirin Treatment   Luigi Amati   Vittorio Pugliese   Emilio Jirillo     87
Interferon-Induced Effector Proteins and Hepatitis C Virus Replication   Michael Frese   Eva Dazert     106
Treatment of Chronic Hepatitis C with Different Genotypes   James Fung   Ching-Lung Lai   Man-Fung Yuen     130
Interferon Treatment of Hepatitis C Virus Infection: From Basic Biology to Clinical Application   Norihiro Furusyo   Masayuki Murata   Jun Hayashi     148
Interferon-Based Therapy for Hepatitis CVirus Infections   Ming-Lung Yu   Wan-Long Chuang     168
Treatment of Chronic Hepatitis C in "Difficult-to-Treat" Patients in the Clinical Setting   Ana Moreno   Rafael Barcena   Carmen Quereda     192
Effects of Combined IFN-Alpha/Ribavirin Treatment in HCV Disease-Related Progression   Davide Festi   Francesca Lodato   Giuseppe Mazzella   Antonio Colecchia     215
Pegylated Interferons: Clinical Applications in the Management of Hepatitis C Infection   S. James Matthews   Christopher McCoy     237
Subject Index     293
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