Heterocyclic Chemistry in Drug Discovery

Heterocyclic Chemistry in Drug Discovery

by Jie Jack Li
     
 

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Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds

Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in

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Overview

Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds

Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own academic and industrial laboratory experience, helping readers avoid common pitfalls.

Heterocyclic Chemistry in Drug Discovery is ideal for readers who want to fully realize the almost limitless potential to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features:

  • Several case studies illustrating the role and application of 3, 4, 5, and 6+ heterocyclic ring systems in drug discovery
  • Step-by-step descriptions of synthetic methods and practical techniques
  • Examination of the physical properties for each heterocycle, including NMR data and quantum calculations
  • Detailed explanations of the complexity and intricacies of reactivity and stability for each class of heterocycles

Heterocyclic Chemistry in Drug Discovery is recommended as a textbook for organic and medicinal chemistry courses, particularly those emphasizing heterocyclic chemistry. The text also serves as a guide for medicinal and process chemists in the pharmaceutical industry, offering them new insights and new paths to explore for effective drug discovery.

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Editorial Reviews

From the Publisher
“The book can also serve as a textbook for undergraduates and graduates, which is highlighted by the inclusion of interesting problem sets.”  (Angew. Chem. Int. Ed, 1 February 2014)

“In summary, both students and experts in the field would find useful information in this book.”  (ChemMedChem, 1 January 2014)

“[Li] has assembled a team of 20 contributing authors from academia and the industry to write this book, which … comes across as a successful fusion of heterocyclic chemistry and drug discovery, from which intending medicinal chemists will derive much benefit, or as Li puts it, a ‘jump-start’ on the competition!.”  (Chemistry in Australia, 1 July 2013)

Product Details

ISBN-13:
9781118148907
Publisher:
Wiley
Publication date:
04/08/2013
Pages:
720
Product dimensions:
7.20(w) x 10.00(h) x 1.50(d)

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