Heterocyclic Chemistry / Edition 5

Paperback (Print)
Buy New
Buy New from BN.com
Used and New from Other Sellers
Used and New from Other Sellers
from $52.52
Usually ships in 1-2 business days
(Save 15%)
Other sellers (Paperback)
  • All (9) from $52.52   
  • New (6) from $52.52   
  • Used (3) from $55.02   


Heterocyclic chemistry is a central part of organic chemistry and biochemistry. The term refers to a particular set of chemical structure characteristics, with many drugs and specialty chemicals, and most agrochemicals, containing these characteristics. Heterocyclic Chemistry by Joule & Mills has established itself as the premier textbook of heterocyclic chemistry, used by high level undergraduates, postgraduates and industrial researchers all over the world. Heterocyclic Chemistry covers the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. It also includes more advanced material, making the book appropriate for postgraduate taught courses and to researchers, either at postgraduate degree level or those working with heterocyclic compounds in industry. Essential teaching material is collected in specific introductory chapters, explaining the principles of heterocyclic reactivity in the simplest terms, suitable either as introductions or as summaries for examination preparation. These chapters are augmented by detailed, systematic discussions of the chemical reactivity of particular heterocyclic systems. References to both primary literature and reviews are given throughout the text, and whilst these are essential for postgraduate teaching and to research workers, they do not interfere with the readability of the text for undergraduate students.

Read More Show Less

Editorial Reviews

From the Publisher
“Overall, this book is recommended as a text for undergraduate and more advanced students on this pervasive, important, and underappreciated topic in chemistry.”  (Journal of Chemical Education, 1 October 2012)

"This excellent book is well written, heavily referenced, and thoroughly indexed. Accordingly, it serves as both an instructional heterocyclic chemistry textbook and a portal to the primary synthetic chemistry literature." (Journal of Medicinal Chemistry, 2011)

"My favourite chapter is the organometallic chemistry that presents an up-to-date treatment of the topic and helps confirms a colleague's observation that ‘With today's techniques one can be convinced that a modern organic chemist can make any small molecule he or she desires.' I particularly like the treatment of the concatenation of five-membered ring systems, an increasingly important area in medicinal chemistry. This chapter proves a real ‘coup de grace'." (Reviews, December 2010)

"In summary, Heterocyclic Chemistry by Joule and Mills is in a class of its own and can be thoroughly recommended as supplementary reading for undergraduate courses and as a first port of call for researchers seeking a quick entry to the extensive heterocyclic literature." (Applied Organometallic Chemistry, 2010)

"My recommendation is, even if you already have the 4th edition, to buy the latest version. At only £39.95 for the paperback version this is outstanding value for money." (Organic Process Research & Development Journal, 2010)

Read More Show Less

Product Details

  • ISBN-13: 9781405133005
  • Publisher: Wiley
  • Publication date: 6/8/2010
  • Edition description: New Edition
  • Edition number: 5
  • Pages: 718
  • Sales rank: 1,126,388
  • Product dimensions: 7.50 (w) x 9.70 (h) x 1.40 (d)

Meet the Author

John Joule is Emeritus Professor in the School of Chemistry, The University of Manchester, UK

Keith Mills spent 25 years in the Medicinal Chemistry and Development Chemistry departments at GlaxoSmithKline, Stevenage, UK, and is now an independent consultant.

Read More Show Less

Table of Contents


Definitions of abbreviations

1. Heterocyclic nomenclature

2. Structures and spectroscopic properties of aromatic heterocycles

3. Substitutions of aromatic heterocycles

4. Organometallic heterocyclic chemistry

5. Methods in heterocyclic chemistry

6. Ring synthesis of aromatic heterocycles

7. Typical reactivity of pyridines, quinolines and isoquinolines

8. Pyridines: reactions and synthesis

9. Quinolines and isoquinolines: reactions and synthesis

10. Typical reactivity of pyrylium and benzopyrylium ions, pyrones and benzopyrones

11. Pyryliums, 2- and 4-pyrones: reactions and synthesis

12. Benzopyryliums, benzopyrones: reactions and synthesis

13. Typical reactivity of the diazines: pyridazine, pyrimidine and pyrazine

14. The diazines: pyridazine, pyrimidine, and pyrazine: reactions and synthesis

15. Typical reactivity of pyrroles, thiophenes, and furans

16. Pyrroles: reactions and synthesis

17. Thiophenes: reactions and synthesis

18. Furans: reactions and synthesis

19. Typical reactivity of indoles, benzo[b]thiophenes, benzo[b]furans, isoindoles, benzo[c]thiophenes and isobenzofurans

20. Indoles: reactions and synthesis

21. Benzo[b]thiophenes and benzo[b]furans: reactions and synthesis

22. Isoindoles, benzo[c]thiophenes and isobenzofurans: reactions and synthesis

23. Typical reactivity of 1,3- and 1,2-azoles and benzo-1,3- and -1,2-azoles

24. 1,3-Azoles: imidazoles, thiazoles, and oxazoles: reactions and synthesis

25. 1,2-Azoles: pyrazoles, isothiazoles, isoxazoles: reactions and synthesis

26. Benzanellated azoles: reactions and synthesis

27. Purines: reactions and synthesis

28. Heterocycles containing a ring-junction nitrogen (bridgehead compounds)

29. Heterocycles containing more than two heteroatoms

30. Saturated and partially unsaturated heterocyclic compounds: reactions and synthesis

31. Special topics

32. Heterocycles in biochemistry; heterocyclic natural products

33. Heterocycles in medicine

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)